Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura

doi:doi:10.11648/j.ajac.20231103.13

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Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura

Published in American Journal of Applied Chemistry (Volume 11, Issue 3)

Received: 20 April 2023 Accepted: 9 May 2023 Published: 6 July 2023

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Abstract

The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω^-1cm²mol^-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).

Published in	American Journal of Applied Chemistry (Volume 11, Issue 3)
DOI	10.11648/j.ajac.20231103.13
Page(s)	86-94
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Schiff Base, Complexes, 2-hydroxybenzaldehyde, 1-naphthylamine, Antimicrobial Activity

References

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APA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. (2023). Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. American Journal of Applied Chemistry, 11(3), 86-94. https://doi.org/10.11648/j.ajac.20231103.13

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ACS Style

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am. J. Appl. Chem. 2023, 11(3), 86-94. doi: 10.11648/j.ajac.20231103.13

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AMA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am J Appl Chem. 2023;11(3):86-94. doi: 10.11648/j.ajac.20231103.13

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@article{10.11648/j.ajac.20231103.13,
  author = {Ibrahim Kani Aminu and Abdulwaris Abdullahi Daura},
  title = {Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {3},
  pages = {86-94},
  doi = {10.11648/j.ajac.20231103.13},
  url = {https://doi.org/10.11648/j.ajac.20231103.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231103.13},
  abstract = {The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).},
 year = {2023}
}

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TY  - JOUR
T1  - Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine
AU  - Ibrahim Kani Aminu
AU  - Abdulwaris Abdullahi Daura
Y1  - 2023/07/06
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231103.13
DO  - 10.11648/j.ajac.20231103.13
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 86
EP  - 94
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231103.13
AB  - The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).
VL  - 11
IS  - 3
ER  -

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Author Information

Ibrahim Kani Aminu

Department of Pure and Industrial Chemistry, Bayero University, Kano, Nigeria
Abdulwaris Abdullahi Daura

Mechanical Engineering Department, Usman Danfodiyo University, Sokoto, Nigeria

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Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. (2023). Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. American Journal of Applied Chemistry, 11(3), 86-94. https://doi.org/10.11648/j.ajac.20231103.13

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ACS Style

Ibrahim Kani Aminu; Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am. J. Appl. Chem. 2023, 11(3), 86-94. doi: 10.11648/j.ajac.20231103.13

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AMA Style

Ibrahim Kani Aminu, Abdulwaris Abdullahi Daura. Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine. Am J Appl Chem. 2023;11(3):86-94. doi: 10.11648/j.ajac.20231103.13

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@article{10.11648/j.ajac.20231103.13,
  author = {Ibrahim Kani Aminu and Abdulwaris Abdullahi Daura},
  title = {Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {3},
  pages = {86-94},
  doi = {10.11648/j.ajac.20231103.13},
  url = {https://doi.org/10.11648/j.ajac.20231103.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231103.13},
  abstract = {The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).},
 year = {2023}
}

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TY  - JOUR
T1  - Synthesis, Characterization and Study of Antimicrobial Activity of Mn(II) and Ni(II) Complexes with Schiff Base Derived from 2-Hydroxy-benzaldehyde and 1-Naphthylamine
AU  - Ibrahim Kani Aminu
AU  - Abdulwaris Abdullahi Daura
Y1  - 2023/07/06
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231103.13
DO  - 10.11648/j.ajac.20231103.13
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 86
EP  - 94
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231103.13
AB  - The Schiff base; 2-hydroxybenzalidene-1-naphthylamine and its Mn(II) and Ni(II) complexes were synthesized and characterized using, conductivity measurement, magnetic susceptibility, elemental analyses, melting point/decomposition temperature, electronic spectral analyses, infrared spectral analysis and solubility test. The Schiff base and its metal complexes were tested for antimicrobial activity. The molar conductance values range (6.52 – 23.1 Ω-1cm2mol-1) revealed non-electrolytic nature of the complexes. The magnetic susceptibility values; 5.91 BM indicated Mn(II) complex as paramagnetic while –Ve indicated Ni(II) complex as diamagnetic. The elemental analyses results revealed slight differences between calculated and observed percentages of values of C, H, and N, which is in line with the proposed structures of the synthesized compounds. The high decomposition temperature range (201 – 223°C) indicated good stability of the complexes. The infrared spectra analysis results suggested that the Schiff base behave as bidentate ligand coordinates to metal ion via azomethine nitrogen and phenolic oxygen. The antimicrobial activity of the Schiff base and its metal complexes were carried out using agar well diffusion method against two bacteria strains; (Salmonella typhi and streptococcus pneumoniae) and two fungal isolates; (Aspergillus fumigatus and Rhizopus species). The results revealed that the Schiff base and its metal complexes exhibited moderate antimicrobial activity as compared with the standard drugs; (Gentamycin and Nystatin).
VL  - 11
IS  - 3
ER  -

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