Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework

Shatakshi Saxena; Punya Saluja; JBM Krishna; Tinku Basu

doi:doi:10.11648/j.am.20211002.12

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Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework

Shatakshi Saxena, Punya Saluja, JBM Krishna, Tinku Basu

Published in Advances in Materials (Volume 10, Issue 2)

Received: 7 December 2020 Accepted: 15 December 2020 Published: 13 July 2021

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Abstract

Environment is witnessing an extensive increase in persistent and bioactive micro pollutants from the last few decades. Since most clinical modalities are flooded with antibiotics, environmental samples such as sewage treatment effluents, surface water and secondary water drainage etc. reveal the presence of bio-recalcitrant antibiotics worldwide, ergo there is a spurring rise in antibiotic resistant microorganisms. In order to circumvent the escalating concentration of amoxicillin (microgram/liter) we contrived a potential metal organic framework (MOF) and lab tested it for catalytic functionality. A zinc-porphyrin MOF using Tetra (4-carboxyphenyl) porphyrin H2TCPP (>97%) as a ligand and Zinc acetate as a metal salt was solvo-thermally synthesized. The morphological and structural characterization were performed using FESEM, XRD, EDAX, FTIR and UV-Visible spectroscopy. The fabricated MOF catalyst exhibits sterling ability of amoxicillin degradation in a dark environment at room temperature, accounting a degradation efficiency of about 97.3% in a 0.1 mg/ml concentration. 90 minutes of catalyst exposure to the antibiotic shows maximum degradation after which there is no further change in amoxicillin concentration. First time we have exploited electrochemical cyclic voltametric (CV) measurement to monitor the degradation process which was validated by FTIR recording, and noticed that the degradation process followed a first order kinetics. We have also discussed the morphological stability of the fabricated Zn porphyrin MOF after antibiotic exposure and reported a comparative outline between catalytic efficiency of different MOF species. High porosity and effective charge transfer between carboxyphenyl) porphyrin ligand to vacant d orbital of Zn⁺² are pivotal factors for effective sorption and degradation of amoxicillin antibiotics dark at room temperature. We would expect the developed Zn porphyrin MOF is very promising for successful commercial application due to its energy efficiency (dark) and simple process for effective degradation of antibiotics.

Published in	Advances in Materials (Volume 10, Issue 2)
DOI	10.11648/j.am.20211002.12
Page(s)	23-30
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Zn Porphyrin MOF, Amoxycillin, Room Temperature Degradation, FTIR Sensing

References

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Shatakshi Saxena, Punya Saluja, JBM Krishna, Tinku Basu. (2021). Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Advances in Materials, 10(2), 23-30. https://doi.org/10.11648/j.am.20211002.12

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ACS Style

Shatakshi Saxena; Punya Saluja; JBM Krishna; Tinku Basu. Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Adv. Mater. 2021, 10(2), 23-30. doi: 10.11648/j.am.20211002.12

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AMA Style

Shatakshi Saxena, Punya Saluja, JBM Krishna, Tinku Basu. Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Adv Mater. 2021;10(2):23-30. doi: 10.11648/j.am.20211002.12

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@article{10.11648/j.am.20211002.12,
  author = {Shatakshi Saxena and Punya Saluja and JBM Krishna and Tinku Basu},
  title = {Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework},
  journal = {Advances in Materials},
  volume = {10},
  number = {2},
  pages = {23-30},
  doi = {10.11648/j.am.20211002.12},
  url = {https://doi.org/10.11648/j.am.20211002.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.am.20211002.12},
  abstract = {Environment is witnessing an extensive increase in persistent and bioactive micro pollutants from the last few decades. Since most clinical modalities are flooded with antibiotics, environmental samples such as sewage treatment effluents, surface water and secondary water drainage etc. reveal the presence of bio-recalcitrant antibiotics worldwide, ergo there is a spurring rise in antibiotic resistant microorganisms. In order to circumvent the escalating concentration of amoxicillin (microgram/liter) we contrived a potential metal organic framework (MOF) and lab tested it for catalytic functionality. A zinc-porphyrin MOF using Tetra (4-carboxyphenyl) porphyrin H2TCPP (>97%) as a ligand and Zinc acetate as a metal salt was solvo-thermally synthesized. The morphological and structural characterization were performed using FESEM, XRD, EDAX, FTIR and UV-Visible spectroscopy. The fabricated MOF catalyst exhibits sterling ability of amoxicillin degradation in a dark environment at room temperature, accounting a degradation efficiency of about 97.3% in a 0.1 mg/ml concentration. 90 minutes of catalyst exposure to the antibiotic shows maximum degradation after which there is no further change in amoxicillin concentration. First time we have exploited electrochemical cyclic voltametric (CV) measurement to monitor the degradation process which was validated by FTIR recording, and noticed that the degradation process followed a first order kinetics. We have also discussed the morphological stability of the fabricated Zn porphyrin MOF after antibiotic exposure and reported a comparative outline between catalytic efficiency of different MOF species. High porosity and effective charge transfer between carboxyphenyl) porphyrin ligand to vacant d orbital of Zn+2 are pivotal factors for effective sorption and degradation of amoxicillin antibiotics dark at room temperature. We would expect the developed Zn porphyrin MOF is very promising for successful commercial application due to its energy efficiency (dark) and simple process for effective degradation of antibiotics.},
 year = {2021}
}

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TY  - JOUR
T1  - Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework
AU  - Shatakshi Saxena
AU  - Punya Saluja
AU  - JBM Krishna
AU  - Tinku Basu
Y1  - 2021/07/13
PY  - 2021
N1  - https://doi.org/10.11648/j.am.20211002.12
DO  - 10.11648/j.am.20211002.12
T2  - Advances in Materials
JF  - Advances in Materials
JO  - Advances in Materials
SP  - 23
EP  - 30
PB  - Science Publishing Group
SN  - 2327-252X
UR  - https://doi.org/10.11648/j.am.20211002.12
AB  - Environment is witnessing an extensive increase in persistent and bioactive micro pollutants from the last few decades. Since most clinical modalities are flooded with antibiotics, environmental samples such as sewage treatment effluents, surface water and secondary water drainage etc. reveal the presence of bio-recalcitrant antibiotics worldwide, ergo there is a spurring rise in antibiotic resistant microorganisms. In order to circumvent the escalating concentration of amoxicillin (microgram/liter) we contrived a potential metal organic framework (MOF) and lab tested it for catalytic functionality. A zinc-porphyrin MOF using Tetra (4-carboxyphenyl) porphyrin H2TCPP (>97%) as a ligand and Zinc acetate as a metal salt was solvo-thermally synthesized. The morphological and structural characterization were performed using FESEM, XRD, EDAX, FTIR and UV-Visible spectroscopy. The fabricated MOF catalyst exhibits sterling ability of amoxicillin degradation in a dark environment at room temperature, accounting a degradation efficiency of about 97.3% in a 0.1 mg/ml concentration. 90 minutes of catalyst exposure to the antibiotic shows maximum degradation after which there is no further change in amoxicillin concentration. First time we have exploited electrochemical cyclic voltametric (CV) measurement to monitor the degradation process which was validated by FTIR recording, and noticed that the degradation process followed a first order kinetics. We have also discussed the morphological stability of the fabricated Zn porphyrin MOF after antibiotic exposure and reported a comparative outline between catalytic efficiency of different MOF species. High porosity and effective charge transfer between carboxyphenyl) porphyrin ligand to vacant d orbital of Zn+2 are pivotal factors for effective sorption and degradation of amoxicillin antibiotics dark at room temperature. We would expect the developed Zn porphyrin MOF is very promising for successful commercial application due to its energy efficiency (dark) and simple process for effective degradation of antibiotics.
VL  - 10
IS  - 2
ER  -

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Author Information

Shatakshi Saxena

Centre for Converging Technologies, University of Rajasthan, Jaipur, India
Punya Saluja

Centre for Converging Technologies, University of Rajasthan, Jaipur, India
JBM Krishna

University Grants Commission, Department of Atomic Energy, Consortium For Scientific Research, Bidhan Nagar, Kolkata, India
Tinku Basu

Amity Centre for Nanomedicine, Amity University, Uttar Pradesh, India

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Shatakshi Saxena, Punya Saluja, JBM Krishna, Tinku Basu. (2021). Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Advances in Materials, 10(2), 23-30. https://doi.org/10.11648/j.am.20211002.12

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ACS Style

Shatakshi Saxena; Punya Saluja; JBM Krishna; Tinku Basu. Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Adv. Mater. 2021, 10(2), 23-30. doi: 10.11648/j.am.20211002.12

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AMA Style

Shatakshi Saxena, Punya Saluja, JBM Krishna, Tinku Basu. Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework. Adv Mater. 2021;10(2):23-30. doi: 10.11648/j.am.20211002.12

Copy | Download

@article{10.11648/j.am.20211002.12,
  author = {Shatakshi Saxena and Punya Saluja and JBM Krishna and Tinku Basu},
  title = {Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework},
  journal = {Advances in Materials},
  volume = {10},
  number = {2},
  pages = {23-30},
  doi = {10.11648/j.am.20211002.12},
  url = {https://doi.org/10.11648/j.am.20211002.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.am.20211002.12},
  abstract = {Environment is witnessing an extensive increase in persistent and bioactive micro pollutants from the last few decades. Since most clinical modalities are flooded with antibiotics, environmental samples such as sewage treatment effluents, surface water and secondary water drainage etc. reveal the presence of bio-recalcitrant antibiotics worldwide, ergo there is a spurring rise in antibiotic resistant microorganisms. In order to circumvent the escalating concentration of amoxicillin (microgram/liter) we contrived a potential metal organic framework (MOF) and lab tested it for catalytic functionality. A zinc-porphyrin MOF using Tetra (4-carboxyphenyl) porphyrin H2TCPP (>97%) as a ligand and Zinc acetate as a metal salt was solvo-thermally synthesized. The morphological and structural characterization were performed using FESEM, XRD, EDAX, FTIR and UV-Visible spectroscopy. The fabricated MOF catalyst exhibits sterling ability of amoxicillin degradation in a dark environment at room temperature, accounting a degradation efficiency of about 97.3% in a 0.1 mg/ml concentration. 90 minutes of catalyst exposure to the antibiotic shows maximum degradation after which there is no further change in amoxicillin concentration. First time we have exploited electrochemical cyclic voltametric (CV) measurement to monitor the degradation process which was validated by FTIR recording, and noticed that the degradation process followed a first order kinetics. We have also discussed the morphological stability of the fabricated Zn porphyrin MOF after antibiotic exposure and reported a comparative outline between catalytic efficiency of different MOF species. High porosity and effective charge transfer between carboxyphenyl) porphyrin ligand to vacant d orbital of Zn+2 are pivotal factors for effective sorption and degradation of amoxicillin antibiotics dark at room temperature. We would expect the developed Zn porphyrin MOF is very promising for successful commercial application due to its energy efficiency (dark) and simple process for effective degradation of antibiotics.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Morphological and Structural Elucidation of Room Temperature Catalytic Degradation of Amoxicillin Antibiotic Using Zinc Porphyrin Metal Organic Framework
AU  - Shatakshi Saxena
AU  - Punya Saluja
AU  - JBM Krishna
AU  - Tinku Basu
Y1  - 2021/07/13
PY  - 2021
N1  - https://doi.org/10.11648/j.am.20211002.12
DO  - 10.11648/j.am.20211002.12
T2  - Advances in Materials
JF  - Advances in Materials
JO  - Advances in Materials
SP  - 23
EP  - 30
PB  - Science Publishing Group
SN  - 2327-252X
UR  - https://doi.org/10.11648/j.am.20211002.12
AB  - Environment is witnessing an extensive increase in persistent and bioactive micro pollutants from the last few decades. Since most clinical modalities are flooded with antibiotics, environmental samples such as sewage treatment effluents, surface water and secondary water drainage etc. reveal the presence of bio-recalcitrant antibiotics worldwide, ergo there is a spurring rise in antibiotic resistant microorganisms. In order to circumvent the escalating concentration of amoxicillin (microgram/liter) we contrived a potential metal organic framework (MOF) and lab tested it for catalytic functionality. A zinc-porphyrin MOF using Tetra (4-carboxyphenyl) porphyrin H2TCPP (>97%) as a ligand and Zinc acetate as a metal salt was solvo-thermally synthesized. The morphological and structural characterization were performed using FESEM, XRD, EDAX, FTIR and UV-Visible spectroscopy. The fabricated MOF catalyst exhibits sterling ability of amoxicillin degradation in a dark environment at room temperature, accounting a degradation efficiency of about 97.3% in a 0.1 mg/ml concentration. 90 minutes of catalyst exposure to the antibiotic shows maximum degradation after which there is no further change in amoxicillin concentration. First time we have exploited electrochemical cyclic voltametric (CV) measurement to monitor the degradation process which was validated by FTIR recording, and noticed that the degradation process followed a first order kinetics. We have also discussed the morphological stability of the fabricated Zn porphyrin MOF after antibiotic exposure and reported a comparative outline between catalytic efficiency of different MOF species. High porosity and effective charge transfer between carboxyphenyl) porphyrin ligand to vacant d orbital of Zn+2 are pivotal factors for effective sorption and degradation of amoxicillin antibiotics dark at room temperature. We would expect the developed Zn porphyrin MOF is very promising for successful commercial application due to its energy efficiency (dark) and simple process for effective degradation of antibiotics.
VL  - 10
IS  - 2
ER  -

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