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Epidemiological and Histopathological Profile of Prostate Cancer in Conakry

Received: 21 September 2023    Accepted: 30 October 2023    Published: 11 November 2023
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Abstract

Introduction: Prostate cancer is the most common male cancer. The aim of this work was to analyze the evolution of the epidemiological and histopathological profile of prostate cancer in the urology department at the Ignace Deen National Hospital in Conakry. Materials and methods: This was a descriptive retrospective study in 10 years, from January 1, 2011 to December 31, 2020. The data was collected from records available in the archives of the Ignace National Hospital Deen of Conakry. Results: 963 cases of prostate cancer were collected, representing 75% of urogenital cancers. We have observed a constant annual growth of cases, with an annual average of 96 cases. The mean age of the patients was 67 ± 13.56 years, with extremes of [47 - 102 years]. Farmers were the most affected with 36.3% of cases; 9.9% of patients (n=92) were smokers. Patients consulted more often with a delay of more than 12 months. Prostatic adenocarcinoma was the most found histological type with 99.8% of cases. More than half of the patients (62%) had a Gleason score of 3+3 (ISUP 1). Conclusion: Prostate cancer remains frequent representing the first urological cancer in Conakry. Prostatic adenocarcinoma is the main histological type. This study encountered difficulties related to the lack of a reliable data collection system.

Published in Cancer Research Journal (Volume 11, Issue 4)
DOI 10.11648/j.crj.20231104.11
Page(s) 122-126
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Prostate Cancer, Conakry, Frenquency, Farmers, Adenocarcinoma

References
[1] International Agency for Research on Cancer. GLOBOCAN 2020: estimated cancer incidence, mortality and prevalence worldwide in 2020 [Internet]. https://gco.iarc.fr/today/data/factsheets/cancers/27-Prostate-fact-sheet.pdf
[2] Grosclaude P., Davin J. L., Neuzillet Y., Coulange C. Evolution of the epidémiology of prostate cancer over 20 years. Progrès en Urologie, 2006, 16: 653-660.
[3] Bergengren O, Pekala KR, Matsoukas K, Fainberg J, Mungovan SF, Bratt O, and al. 2022 Update on Prostate Cancer Epidemiology and Risk Factors - A Systematic Review. Eur Urol, 2023; S0302-2838 (23) 02786-0. https://doi.org/10.1016/j.eururo.2023.04.021
[4] Gueye SM, Jalloh M, Labou I, Niang L, Kane R, Ndoye M. Clinical profile of prostate cancer in Senegal. Afr J Urol 2004; 10: 203—7.
[5] Ouattara A, Hodonou R, Avakoudjo J, Cisse D, Zango B, Gandaho I, and al. Epidemiology of urological cancers at the Hubert Koutoukou Maga Cotonou National University Hospital Center. Benign. Analysis of a hospital series of 158 cases. Prog Urol 2012. 22: 261–5. https://doi.org/10.1016/j.purol.2011.12.003
[6] Diallo AB, Bah I, Barry AM, Dombeu NY, Barry M, Diallo MB. Epidemiological characteristics of prostate cancer in Guinea. African Journal of Urology 2008, 14 (3) : 161-167.
[7] Sritharan J, MacLeod JS, McLeod CB, Peter A, Demers PA. Risk of prostate cancer by occupation in the Occupational Disease Surveillance System of Ontario, Canada. Revue PSPMC 2019, 39 (5): 195 -205. https://doi.org/10.24095/hpcdp.39.5.02f
[8] Sauve JF, Lavoue J, Parent ME. Occupation, industry and the risk of prostate cancer: a case-control in Montréal, Canada. Environmental Health. 2016; 15 (1): 100. https://doi.org/10.1186/s12940-016-0185-1
[9] Zeegers MP, Friesema IH, Goldbohm R, Van Den Brandt P. A prospective study of occupation and prostate cancer risk. Journal of Occupational and Environmental Medicine. 2004, 46(3): 271-279. https://doi.org/10.1097/01.jom.0000116961.48464.6b
[10] Ragin C, Davis-Reyes B, Tadesse H, Daniels D, Bunker CH, Jackson M, and al. Farming, reported pesticide use, and prostate cancer. American Journal of Men’s Health. 2013; 7(2): 102-109. https://doi.org/10.1177/1557988312458792
[11] Parent ME, Desy M, Siemiatycki J. Does exposure to agriculture chemicals increase the risk of prostate cancer among farmers? McGill Journal of Medicine. 2009; 12(1): 70-77.
[12] Dosemeci M, Hayes RB, Vetter R, Hoover RN, Tucker M, Engin K et al. Occupational physical activity, socioeconomic status, and risks of 15 cancer sites in Turkey. Cancer Causes Control. 1993, 4: 313-321. https://doi.org/10.1007/bf00051333
[13] Liu Y, Hu F, Li D, Wang F, Zhu L, Chen W, et al. Does physical activity reduce the risk of prostate cancer? A systematic review and metaanalysis. European Urology. 2011, 60: 1029-1044. https://doi.org/10.1016/j.eururo.2011.07.007
[14] Van der Gulden JW, Kolk JJ, Verbeek AL. Work environment and prostate cancer risk. Prostate. 1995; 27(5): 250- 257. https://doi.org/10.1002/pros.2990270504
[15] Le Masters GK, Genaidy AM, Succop P, Deddens J, Sobeih T, Barriera-Viruet H, and al. Cancer risk among firefighters: a review and meta-analysis of 32 studies. Journal of Occupational and Environmental Medicine. 2006; 48(11): 1189-1202. https://doi.org/10.1097/01.jom.0000246229.68697.90
[16] International Center for Research on Cancer Lyon, 2018. Cancers attributable to lifestyle and the environment in metropolitan France. Online at: https://gco.iarc.fr/includes/PAF/PAF_FR_report.pdf
[17] Campedel L, Kossaï M, Blanc-Durand P, Rouprêt M, Seisen T, Compérat E, et al. Neuroendocrine prostate cancer: Natural history, molecular features, therapeutic management and future directions. Bull Cancer. 2017, 104 (9): 789-799. https://doi.org/10.1016/j.bulcan.2017.05.007
[18] Dubois F, Croué A, Ouacel F, Chautard D, Saint-André J-P, Azzouzi AR. Prostate sarcoma. EMC (Elsevier Masson SAS, Paris), Urologie, 18-560-E-10, 2008. https://doi.org/10.1016/S1762-0953(19)73312-3
[19] Amégbor K, Seddoh TY, Tengue K, Songne-Gnamkoulamba B, Napo-Koura G, James K. Epidemiology and histopronostic of prostatic cancer in Togo: About 202 cases diagnosed at the laboratory of pathology of the Tokoin teaching hospital of Lome. Progrès en Urologie. 2009 19 (2): 112–115. https://doi.org/10.1016/j.purol.2008.10.008
Cite This Article
  • APA Style

    Oury, D. T. M., Bissiriou, B. M., Demba, C., Diodirine, A. A., Diawo, B. M., et al. (2023). Epidemiological and Histopathological Profile of Prostate Cancer in Conakry. Cancer Research Journal, 11(4), 122-126. https://doi.org/10.11648/j.crj.20231104.11

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    ACS Style

    Oury, D. T. M.; Bissiriou, B. M.; Demba, C.; Diodirine, A. A.; Diawo, B. M., et al. Epidemiological and Histopathological Profile of Prostate Cancer in Conakry. Cancer Res. J. 2023, 11(4), 122-126. doi: 10.11648/j.crj.20231104.11

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    AMA Style

    Oury DTM, Bissiriou BM, Demba C, Diodirine AA, Diawo BM, et al. Epidemiological and Histopathological Profile of Prostate Cancer in Conakry. Cancer Res J. 2023;11(4):122-126. doi: 10.11648/j.crj.20231104.11

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  • @article{10.11648/j.crj.20231104.11,
      author = {Diallo Thierno Mamadou Oury and Bah Mamadou Bissiriou and Cissé Demba and Agossou Ahouéfa Diodirine and Bah Mamadou Diawo and Diallo Alimou and Diallo Thierno Oumar and Keita Youssouf and Kolié Aimé and Diallo Abdoulaye Bobo and Bah Oumar Raphiou},
      title = {Epidemiological and Histopathological Profile of Prostate Cancer in Conakry},
      journal = {Cancer Research Journal},
      volume = {11},
      number = {4},
      pages = {122-126},
      doi = {10.11648/j.crj.20231104.11},
      url = {https://doi.org/10.11648/j.crj.20231104.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20231104.11},
      abstract = {Introduction: Prostate cancer is the most common male cancer. The aim of this work was to analyze the evolution of the epidemiological and histopathological profile of prostate cancer in the urology department at the Ignace Deen National Hospital in Conakry. Materials and methods: This was a descriptive retrospective study in 10 years, from January 1, 2011 to December 31, 2020. The data was collected from records available in the archives of the Ignace National Hospital Deen of Conakry. Results: 963 cases of prostate cancer were collected, representing 75% of urogenital cancers. We have observed a constant annual growth of cases, with an annual average of 96 cases. The mean age of the patients was 67 ± 13.56 years, with extremes of [47 - 102 years]. Farmers were the most affected with 36.3% of cases; 9.9% of patients (n=92) were smokers. Patients consulted more often with a delay of more than 12 months. Prostatic adenocarcinoma was the most found histological type with 99.8% of cases. More than half of the patients (62%) had a Gleason score of 3+3 (ISUP 1). Conclusion: Prostate cancer remains frequent representing the first urological cancer in Conakry. Prostatic adenocarcinoma is the main histological type. This study encountered difficulties related to the lack of a reliable data collection system.
    },
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Epidemiological and Histopathological Profile of Prostate Cancer in Conakry
    AU  - Diallo Thierno Mamadou Oury
    AU  - Bah Mamadou Bissiriou
    AU  - Cissé Demba
    AU  - Agossou Ahouéfa Diodirine
    AU  - Bah Mamadou Diawo
    AU  - Diallo Alimou
    AU  - Diallo Thierno Oumar
    AU  - Keita Youssouf
    AU  - Kolié Aimé
    AU  - Diallo Abdoulaye Bobo
    AU  - Bah Oumar Raphiou
    Y1  - 2023/11/11
    PY  - 2023
    N1  - https://doi.org/10.11648/j.crj.20231104.11
    DO  - 10.11648/j.crj.20231104.11
    T2  - Cancer Research Journal
    JF  - Cancer Research Journal
    JO  - Cancer Research Journal
    SP  - 122
    EP  - 126
    PB  - Science Publishing Group
    SN  - 2330-8214
    UR  - https://doi.org/10.11648/j.crj.20231104.11
    AB  - Introduction: Prostate cancer is the most common male cancer. The aim of this work was to analyze the evolution of the epidemiological and histopathological profile of prostate cancer in the urology department at the Ignace Deen National Hospital in Conakry. Materials and methods: This was a descriptive retrospective study in 10 years, from January 1, 2011 to December 31, 2020. The data was collected from records available in the archives of the Ignace National Hospital Deen of Conakry. Results: 963 cases of prostate cancer were collected, representing 75% of urogenital cancers. We have observed a constant annual growth of cases, with an annual average of 96 cases. The mean age of the patients was 67 ± 13.56 years, with extremes of [47 - 102 years]. Farmers were the most affected with 36.3% of cases; 9.9% of patients (n=92) were smokers. Patients consulted more often with a delay of more than 12 months. Prostatic adenocarcinoma was the most found histological type with 99.8% of cases. More than half of the patients (62%) had a Gleason score of 3+3 (ISUP 1). Conclusion: Prostate cancer remains frequent representing the first urological cancer in Conakry. Prostatic adenocarcinoma is the main histological type. This study encountered difficulties related to the lack of a reliable data collection system.
    
    VL  - 11
    IS  - 4
    ER  - 

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Author Information
  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

  • Urology-Andrology Department, Ignace Deen National Hospital in Conakry, Conakry, Guinea

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