Background: SARS-CoV-2disease (COVID-19) has become pandemic all over world. This study aimed to investigate the clinical characteristics and severe outcomes of COVID-19 patients with high body mass index (BMI). Methods: A cohort study included 114 adult patients confirmed COVID-19 were classified by BMI levels on admission: overweight (25–29.9 kg/m2), and obesity (four categories: 30–34.9 kg/m2, 35–39.9 kg/m2, 40–44.9 kg/m2, and ≥45 kg/m2). The rate of pneumonia, severe pneumonia and ICU admission were our primary outcomes, complications and length of hospital stay were the secondary outcome. Results: In Qena University isolation Hospital, study was conducted in 114 patients confirmed COVID-19. The mean age of patients was 42.1±11.1 years and males were 53.5%. Hypertension and diabetes common comorbidities, 54 patients (47.3%) had pneumonia and 28 patients (24.6%) had progressed to severe pneumonia with significant difference across BMI level (p<0.05). The rates of admission to ICU were 13.1%, acute kidney injury (7.8%), acute liver injury (5.2%) and shock (7%), ICU mortality with BMI 40–44.9 kg/m2 and ≥45 kg/m2 showed 100% mortality among patients admitted (p <0.001), with median of days of hospitalization (12days). Multivariable analysis demonstrated that; BMI (increase one kg/m2), Hypertension, Dyslipidemia, Lymphopenia, CRP and IL6 independent risk factors for severe illness. Conclusion: Serious outcomes such as severe pneumonia, acute kidney injury and ICU mortality are associated with obesity and COVID-19. Call for future studies to find out the correlation between obesity and COVID-19.
| Published in | International Journal of Anesthesia and Clinical Medicine (Volume 9, Issue 1) |
| DOI | 10.11648/j.ijacm.20210901.14 |
| Page(s) | 16-22 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
High BMI, COVID-19, Sever Pneumonia, IL6
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APA Style
Gad Sayed Gad Abdel-Gelil. (2021). High Body Mass Index and Severity of Coronavirus Disease 2019 (COVID-19): A Cohort Study. International Journal of Anesthesia and Clinical Medicine, 9(1), 16-22. https://doi.org/10.11648/j.ijacm.20210901.14
ACS Style
Gad Sayed Gad Abdel-Gelil. High Body Mass Index and Severity of Coronavirus Disease 2019 (COVID-19): A Cohort Study. Int. J. Anesth. Clin. Med. 2021, 9(1), 16-22. doi: 10.11648/j.ijacm.20210901.14
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Download@article{10.11648/j.ijacm.20210901.14,
author = {Gad Sayed Gad Abdel-Gelil},
title = {High Body Mass Index and Severity of Coronavirus Disease 2019 (COVID-19): A Cohort Study},
journal = {International Journal of Anesthesia and Clinical Medicine},
volume = {9},
number = {1},
pages = {16-22},
doi = {10.11648/j.ijacm.20210901.14},
url = {https://doi.org/10.11648/j.ijacm.20210901.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20210901.14},
abstract = {Background: SARS-CoV-2disease (COVID-19) has become pandemic all over world. This study aimed to investigate the clinical characteristics and severe outcomes of COVID-19 patients with high body mass index (BMI). Methods: A cohort study included 114 adult patients confirmed COVID-19 were classified by BMI levels on admission: overweight (25–29.9 kg/m2), and obesity (four categories: 30–34.9 kg/m2, 35–39.9 kg/m2, 40–44.9 kg/m2, and ≥45 kg/m2). The rate of pneumonia, severe pneumonia and ICU admission were our primary outcomes, complications and length of hospital stay were the secondary outcome. Results: In Qena University isolation Hospital, study was conducted in 114 patients confirmed COVID-19. The mean age of patients was 42.1±11.1 years and males were 53.5%. Hypertension and diabetes common comorbidities, 54 patients (47.3%) had pneumonia and 28 patients (24.6%) had progressed to severe pneumonia with significant difference across BMI level (p2 and ≥45 kg/m2 showed 100% mortality among patients admitted (p 2), Hypertension, Dyslipidemia, Lymphopenia, CRP and IL6 independent risk factors for severe illness. Conclusion: Serious outcomes such as severe pneumonia, acute kidney injury and ICU mortality are associated with obesity and COVID-19. Call for future studies to find out the correlation between obesity and COVID-19.},
year = {2021}
}
TY - JOUR T1 - High Body Mass Index and Severity of Coronavirus Disease 2019 (COVID-19): A Cohort Study AU - Gad Sayed Gad Abdel-Gelil Y1 - 2021/05/15 PY - 2021 N1 - https://doi.org/10.11648/j.ijacm.20210901.14 DO - 10.11648/j.ijacm.20210901.14 T2 - International Journal of Anesthesia and Clinical Medicine JF - International Journal of Anesthesia and Clinical Medicine JO - International Journal of Anesthesia and Clinical Medicine SP - 16 EP - 22 PB - Science Publishing Group SN - 2997-2698 UR - https://doi.org/10.11648/j.ijacm.20210901.14 AB - Background: SARS-CoV-2disease (COVID-19) has become pandemic all over world. This study aimed to investigate the clinical characteristics and severe outcomes of COVID-19 patients with high body mass index (BMI). Methods: A cohort study included 114 adult patients confirmed COVID-19 were classified by BMI levels on admission: overweight (25–29.9 kg/m2), and obesity (four categories: 30–34.9 kg/m2, 35–39.9 kg/m2, 40–44.9 kg/m2, and ≥45 kg/m2). The rate of pneumonia, severe pneumonia and ICU admission were our primary outcomes, complications and length of hospital stay were the secondary outcome. Results: In Qena University isolation Hospital, study was conducted in 114 patients confirmed COVID-19. The mean age of patients was 42.1±11.1 years and males were 53.5%. Hypertension and diabetes common comorbidities, 54 patients (47.3%) had pneumonia and 28 patients (24.6%) had progressed to severe pneumonia with significant difference across BMI level (p2 and ≥45 kg/m2 showed 100% mortality among patients admitted (p 2), Hypertension, Dyslipidemia, Lymphopenia, CRP and IL6 independent risk factors for severe illness. Conclusion: Serious outcomes such as severe pneumonia, acute kidney injury and ICU mortality are associated with obesity and COVID-19. Call for future studies to find out the correlation between obesity and COVID-19. VL - 9 IS - 1 ER -
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