Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation

Abbas Alramzi; Maysoun Kassem; Ashraf Barghash; Sara Khraibut

doi:doi:10.11648/j.ijcoms.20220801.12

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Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation

Abbas Alramzi, Maysoun Kassem, Ashraf Barghash, Sara Khraibut

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 8, Issue 1)

Received: 6 April 2022 Accepted: 4 May 2022 Published: 24 May 2022

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Abstract

Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 8, Issue 1)
DOI	10.11648/j.ijcoms.20220801.12
Page(s)	5-7
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Human Papilloma Virus (HPV), Squamous Papilloma, Carcinoma, Malignancy

References

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[2]	Penmatsa Chaitanya, Satyam Martha, Ramachandran Punithvathy, Madhusudhan Reddy (2018): Squamous Papilloma on Hard Palate: Case Report and Literature Review. Int J Clin Pediatr 11 (3): 244-246.
[3]	Gaspare Palaia, Chiara Ciolfi, Alessandro Del Vecchio, Alessandro Ciolfi, Gianluca Tenore, Umberto Romeo (2021): Prevention of Recurrence of Oral HPV-Related Lesions: Systematic Review of the Literature and Meta-Analysis. Appl. Sci, 11 (9), 4194.
[4]	S R Prabhu, D F Wilson (2013): Human papillomavirus and oral disease - emerging evidence: a review. Aust Dent J; 58: 2-10; quiz 125.
[5]	Ena Pešut, Anamaria Ðuki´c, Lucija Luli´c, Josipa Skelin, Ivana Šimi´c, Nina Milutin Gašperov, V jekoslav Tomai´c, Ivan Sabol and Magdalena Grce: Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge (2021): Viruses, 13 (11), 2234.
[6]	Arnaud John Kombe Kombe, Bofeng Li, Ayesha Zahid, Hylemariam Mihiretie Mengist, Guy-Armel Bounda, Ying Zhou, Tengchuan Jin (2021): Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation, Front Public Health, 8: 552028.
[7]	Haly Karen Holmes, Amir Afrogeh, Henry Adeola, Faheema Kimmie-Dhansay, Mark E Engel (2021): Prevalence and distribution of HPV infection and subtypes in oral squamous cell carcinoma in Africa: a systematic review protocol, BMJ Open, 11 (7): e049922.
[8]	Sana Khaled, Santosh R. Bharadwaj, Bushraanjum, D. Satyanarayana (2020): Verrucopapillary Lesions of the Oral Cavity: A Review, Inter Healthcare Res J; 4 (7): RV1-RV7.
[9]	Irem Kucukyıldız, Mujdegul Karaca, Utku Akgor, Murat Turkyılmaz, Bekir Keskinkılıc, Fatih Kara, Nejat Ozgul, Murat Gultekin (2022): Endocervical polyps in high risk human papillomavirus infections, Ginekologia Polska, 93 (1): 7–10.
[10]	Daniela Cochicho, Rui Gil da Costa, Ana Felix (2021): Exploring the roles of HPV16 variants in head and neck squamous cell carcinoma: current challenges and opportunities, Virol J 18 (217).
[11]	Sasha J. Betz (2019): HPV-Related Papillary Lesions of the Oral Mucosa: A Review, Head and Neck Pathology, 13 (1): 80–90.
[12]	Min Zhao (2022): Management of large multiple oral papillary lesions suspected Acanthosis Nigricans: a case report, Bulletin of the National Research Centre, 46 (12).
[13]	Srinivas Nallanchakrava, Naga Sreebala, Basavaraj, Farheena Sindgi (2018): Laser Excision of Focal Epithelial Hyperplasia (Heck’s Disease): A Rare Case Report, Inter J of Clinic Pediatric Dentistry; 11 (6): 526-528.
[14]	O Malard, P Corre, F Jégoux, N Durand, B Dréno, C Beauvillain, F Espitalier (2010): Surgical repair of labial defect, Eur Ann Otorhinolaryngol Head Neck Dis; 127 (2): 49-62.

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APA Style

Abbas Alramzi, Maysoun Kassem, Ashraf Barghash, Sara Khraibut. (2022). Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. International Journal of Clinical Oral and Maxillofacial Surgery, 8(1), 5-7. https://doi.org/10.11648/j.ijcoms.20220801.12

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ACS Style

Abbas Alramzi; Maysoun Kassem; Ashraf Barghash; Sara Khraibut. Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. Int. J. Clin. Oral Maxillofac. Surg. 2022, 8(1), 5-7. doi: 10.11648/j.ijcoms.20220801.12

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AMA Style

Abbas Alramzi, Maysoun Kassem, Ashraf Barghash, Sara Khraibut. Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. Int J Clin Oral Maxillofac Surg. 2022;8(1):5-7. doi: 10.11648/j.ijcoms.20220801.12

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@article{10.11648/j.ijcoms.20220801.12,
  author = {Abbas Alramzi and Maysoun Kassem and Ashraf Barghash and Sara Khraibut},
  title = {Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {8},
  number = {1},
  pages = {5-7},
  doi = {10.11648/j.ijcoms.20220801.12},
  url = {https://doi.org/10.11648/j.ijcoms.20220801.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20220801.12},
  abstract = {Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.},
 year = {2022}
}

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TY  - JOUR
T1  - Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation
AU  - Abbas Alramzi
AU  - Maysoun Kassem
AU  - Ashraf Barghash
AU  - Sara Khraibut
Y1  - 2022/05/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcoms.20220801.12
DO  - 10.11648/j.ijcoms.20220801.12
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 5
EP  - 7
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20220801.12
AB  - Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.
VL  - 8
IS  - 1
ER  -

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Author Information

Abbas Alramzi

Unit of Oral and Maxillofacial Surgery, Bneid alQar Specialty Dental Centre, Capital Health District, Kuwait City, Kuwait
Maysoun Kassem

Unit of Oral and Maxillofacial Surgery, Bneid alQar Specialty Dental Centre, Capital Health District, Kuwait City, Kuwait
Ashraf Barghash

Unit of Oral and Maxillofacial Surgery, Bneid alQar Specialty Dental Centre, Capital Health District, Kuwait City, Kuwait
Sara Khraibut

Qortuba Polyclinic, Capital Health District, Kuwait City, Kuwait

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APA Style

Abbas Alramzi, Maysoun Kassem, Ashraf Barghash, Sara Khraibut. (2022). Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. International Journal of Clinical Oral and Maxillofacial Surgery, 8(1), 5-7. https://doi.org/10.11648/j.ijcoms.20220801.12

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ACS Style

Abbas Alramzi; Maysoun Kassem; Ashraf Barghash; Sara Khraibut. Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. Int. J. Clin. Oral Maxillofac. Surg. 2022, 8(1), 5-7. doi: 10.11648/j.ijcoms.20220801.12

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AMA Style

Abbas Alramzi, Maysoun Kassem, Ashraf Barghash, Sara Khraibut. Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation. Int J Clin Oral Maxillofac Surg. 2022;8(1):5-7. doi: 10.11648/j.ijcoms.20220801.12

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@article{10.11648/j.ijcoms.20220801.12,
  author = {Abbas Alramzi and Maysoun Kassem and Ashraf Barghash and Sara Khraibut},
  title = {Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {8},
  number = {1},
  pages = {5-7},
  doi = {10.11648/j.ijcoms.20220801.12},
  url = {https://doi.org/10.11648/j.ijcoms.20220801.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20220801.12},
  abstract = {Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.},
 year = {2022}
}

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TY  - JOUR
T1  - Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation
AU  - Abbas Alramzi
AU  - Maysoun Kassem
AU  - Ashraf Barghash
AU  - Sara Khraibut
Y1  - 2022/05/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcoms.20220801.12
DO  - 10.11648/j.ijcoms.20220801.12
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 5
EP  - 7
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20220801.12
AB  - Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.
VL  - 8
IS  - 1
ER  -

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