An Emerging Clinical Form of Acute Pancreatitis in Covid-19

Meriem Atrassi; Karima Ryouni; Dalal Ben Sabbahia; Abdelhak Abkari

doi:doi:10.11648/j.ijg.20210502.13

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An Emerging Clinical Form of Acute Pancreatitis in Covid-19

Meriem Atrassi, Karima Ryouni, Dalal Ben Sabbahia, Abdelhak Abkari

Published in International Journal of Gastroenterology (Volume 5, Issue 2)

Received: 4 July 2021 Accepted: 27 July 2021 Published: 4 August 2021

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Abstract

Background: As the global severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic continues, new clinical forms of the disease continue to emerge. While the coronavirus is responsible for gastrointestinal symptoms and acute hepatitis, researchers at the Royal University Hospital of Liverpool say they have identified cases of COVID-19-linked pancreatitis in young patients with COVID-19. Objectives: To establish influence of concomitant COVID-19 on clinical presentation and treatment strategy of patients with AP. Methods: This is a case report of pediatric patient admitted to a Pediatric Gastroenterology Unit, A. Harouchi Hospital, CHU Ibn Rochd, Casablanca, Morocco in October 2020 during the COVID-19 pandemic. Results: We report the observation of a 16-year-old girl, who received symptomatic outpatient treatment for influenza-like illness with a fever of 38.5°C before rapidly evolving in 1 week to stage E pancreatitis, where a SARS-COV2 IgG and IgM viral serology was requested coming back positive with a negative nasopharyngeal PCR covid. Conclusion: In conclusion, pancreatitis caused by SARS-CoV-2 is a real but rare entity; in fact COVID-19 can present as pancreatitis. This case highlights acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. This diagnosis is important for adequate treatment and better management of systemic repercussions, such as SIRS, decreasing SARS-CoV-2 mortality.

Published in	International Journal of Gastroenterology (Volume 5, Issue 2)
DOI	10.11648/j.ijg.20210502.13
Page(s)	53-56
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Pancreatitis, COVID-19, SARS-COV2, Gastroenterology

References

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[3]	Wang T, Du Z, Zhu F, et al. Comorbidities and multi-organ injuries in the treatment of COVID-19. Lancet 2020; 395: e52.
[4]	Zhang Y, Xiao M, Zhang S, et al. Coagulopathy and antiphospholipid antibodies in patients with COVID-19. N Engl J Med 2020; 382: e38.
[5]	Wang F, Wang H, Fan J, Zhang Y, Wang H, Zhao Q. Pancreatic injury patterns in patients with COVID-19 pneumonia. Gastroenterology 2020; 159: 367-70.
[6]	Mukherjee R, Smith A, Sutton R. COVID-19-related pancreatic injury. Br J Surg 2020; 107: e190.
[7]	Patel KP, Patel KPA, Vunnam RR, et al. Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19. J Clin Virol. 2020; 128: 104386.
[8]	Suspected case of COVID-19-associated pancreatitis in a child Brian C. Alloway, BA a, Susan K. Yaeger, MD b, Richard J. Mazzaccaro, MD, PhD c, Tibisay Villalobos, MD d, Steven G. Hardy, MD, USA.
[9]	Acute pancreatitis in children hospitalized with COVID-19 Kelly Suchman, Kara L. Raphael, Yan Liu, Diana Wee, Arvind J. Trindade, North well COVID-19 Research Consortium.
[10]	Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109: 102433.
[11]	Gupta, Rohit MD, DM; Meena, Kiran PhD; Patnaik, Itish MD, DM; Kumar, Ashok MD, DM. ACE2 expression in the pancreas and association with COVID-19 Infection (2020), 10.1097/MPA.0000000000001698. Pancreas: January 2021 - Volume 50 - Issue 1 - p e1-e2.
[12]	Schepis, T. et al. SARS- CoV2 RNA detection in a pancreatic pseudo cyst sample. Pancreatology 20, 1011–1012 (2020).
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[14]	Revue autopsique de 5 patients décédés du COVID S. Bessis Hôpital Raymond-Poincaré, Garches, France.
[15]	Difficultés d’interprétation de sérologieCOVID-19, à propos d’un cas Challenge in interpreting COVID-19 serology. Case report A. Lebuisson 2021.

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APA Style

Meriem Atrassi, Karima Ryouni, Dalal Ben Sabbahia, Abdelhak Abkari. (2021). An Emerging Clinical Form of Acute Pancreatitis in Covid-19. International Journal of Gastroenterology, 5(2), 53-56. https://doi.org/10.11648/j.ijg.20210502.13

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ACS Style

Meriem Atrassi; Karima Ryouni; Dalal Ben Sabbahia; Abdelhak Abkari. An Emerging Clinical Form of Acute Pancreatitis in Covid-19. Int. J. Gastroenterol. 2021, 5(2), 53-56. doi: 10.11648/j.ijg.20210502.13

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AMA Style

Meriem Atrassi, Karima Ryouni, Dalal Ben Sabbahia, Abdelhak Abkari. An Emerging Clinical Form of Acute Pancreatitis in Covid-19. Int J Gastroenterol. 2021;5(2):53-56. doi: 10.11648/j.ijg.20210502.13

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@article{10.11648/j.ijg.20210502.13,
  author = {Meriem Atrassi and Karima Ryouni and Dalal Ben Sabbahia and Abdelhak Abkari},
  title = {An Emerging Clinical Form of Acute Pancreatitis in Covid-19},
  journal = {International Journal of Gastroenterology},
  volume = {5},
  number = {2},
  pages = {53-56},
  doi = {10.11648/j.ijg.20210502.13},
  url = {https://doi.org/10.11648/j.ijg.20210502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20210502.13},
  abstract = {Background: As the global severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic continues, new clinical forms of the disease continue to emerge. While the coronavirus is responsible for gastrointestinal symptoms and acute hepatitis, researchers at the Royal University Hospital of Liverpool say they have identified cases of COVID-19-linked pancreatitis in young patients with COVID-19. Objectives: To establish influence of concomitant COVID-19 on clinical presentation and treatment strategy of patients with AP. Methods: This is a case report of pediatric patient admitted to a Pediatric Gastroenterology Unit, A. Harouchi Hospital, CHU Ibn Rochd, Casablanca, Morocco in October 2020 during the COVID-19 pandemic. Results: We report the observation of a 16-year-old girl, who received symptomatic outpatient treatment for influenza-like illness with a fever of 38.5°C before rapidly evolving in 1 week to stage E pancreatitis, where a SARS-COV2 IgG and IgM viral serology was requested coming back positive with a negative nasopharyngeal PCR covid. Conclusion: In conclusion, pancreatitis caused by SARS-CoV-2 is a real but rare entity; in fact COVID-19 can present as pancreatitis. This case highlights acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. This diagnosis is important for adequate treatment and better management of systemic repercussions, such as SIRS, decreasing SARS-CoV-2 mortality.},
 year = {2021}
}

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TY  - JOUR
T1  - An Emerging Clinical Form of Acute Pancreatitis in Covid-19
AU  - Meriem Atrassi
AU  - Karima Ryouni
AU  - Dalal Ben Sabbahia
AU  - Abdelhak Abkari
Y1  - 2021/08/04
PY  - 2021
N1  - https://doi.org/10.11648/j.ijg.20210502.13
DO  - 10.11648/j.ijg.20210502.13
T2  - International Journal of Gastroenterology
JF  - International Journal of Gastroenterology
JO  - International Journal of Gastroenterology
SP  - 53
EP  - 56
PB  - Science Publishing Group
SN  - 2640-169X
UR  - https://doi.org/10.11648/j.ijg.20210502.13
AB  - Background: As the global severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic continues, new clinical forms of the disease continue to emerge. While the coronavirus is responsible for gastrointestinal symptoms and acute hepatitis, researchers at the Royal University Hospital of Liverpool say they have identified cases of COVID-19-linked pancreatitis in young patients with COVID-19. Objectives: To establish influence of concomitant COVID-19 on clinical presentation and treatment strategy of patients with AP. Methods: This is a case report of pediatric patient admitted to a Pediatric Gastroenterology Unit, A. Harouchi Hospital, CHU Ibn Rochd, Casablanca, Morocco in October 2020 during the COVID-19 pandemic. Results: We report the observation of a 16-year-old girl, who received symptomatic outpatient treatment for influenza-like illness with a fever of 38.5°C before rapidly evolving in 1 week to stage E pancreatitis, where a SARS-COV2 IgG and IgM viral serology was requested coming back positive with a negative nasopharyngeal PCR covid. Conclusion: In conclusion, pancreatitis caused by SARS-CoV-2 is a real but rare entity; in fact COVID-19 can present as pancreatitis. This case highlights acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. This diagnosis is important for adequate treatment and better management of systemic repercussions, such as SIRS, decreasing SARS-CoV-2 mortality.
VL  - 5
IS  - 2
ER  -

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Author Information

Meriem Atrassi

Pediatric Gastroenterology Unit, Pediatric Service 3, A. Harouchi Hospital, CHU Ibn Rochd, Hassan II University, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco
Karima Ryouni

Pediatric Gastroenterology Unit, Pediatric Service 3, A. Harouchi Hospital, CHU Ibn Rochd, Hassan II University, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco
Dalal Ben Sabbahia

Pediatric Gastroenterology Unit, Pediatric Service 3, A. Harouchi Hospital, CHU Ibn Rochd, Hassan II University, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco
Abdelhak Abkari

Pediatric Gastroenterology Unit, Pediatric Service 3, A. Harouchi Hospital, CHU Ibn Rochd, Hassan II University, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, Morocco

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APA Style

Meriem Atrassi, Karima Ryouni, Dalal Ben Sabbahia, Abdelhak Abkari. (2021). An Emerging Clinical Form of Acute Pancreatitis in Covid-19. International Journal of Gastroenterology, 5(2), 53-56. https://doi.org/10.11648/j.ijg.20210502.13

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ACS Style

Meriem Atrassi; Karima Ryouni; Dalal Ben Sabbahia; Abdelhak Abkari. An Emerging Clinical Form of Acute Pancreatitis in Covid-19. Int. J. Gastroenterol. 2021, 5(2), 53-56. doi: 10.11648/j.ijg.20210502.13

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AMA Style

Meriem Atrassi, Karima Ryouni, Dalal Ben Sabbahia, Abdelhak Abkari. An Emerging Clinical Form of Acute Pancreatitis in Covid-19. Int J Gastroenterol. 2021;5(2):53-56. doi: 10.11648/j.ijg.20210502.13

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@article{10.11648/j.ijg.20210502.13,
  author = {Meriem Atrassi and Karima Ryouni and Dalal Ben Sabbahia and Abdelhak Abkari},
  title = {An Emerging Clinical Form of Acute Pancreatitis in Covid-19},
  journal = {International Journal of Gastroenterology},
  volume = {5},
  number = {2},
  pages = {53-56},
  doi = {10.11648/j.ijg.20210502.13},
  url = {https://doi.org/10.11648/j.ijg.20210502.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20210502.13},
  abstract = {Background: As the global severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic continues, new clinical forms of the disease continue to emerge. While the coronavirus is responsible for gastrointestinal symptoms and acute hepatitis, researchers at the Royal University Hospital of Liverpool say they have identified cases of COVID-19-linked pancreatitis in young patients with COVID-19. Objectives: To establish influence of concomitant COVID-19 on clinical presentation and treatment strategy of patients with AP. Methods: This is a case report of pediatric patient admitted to a Pediatric Gastroenterology Unit, A. Harouchi Hospital, CHU Ibn Rochd, Casablanca, Morocco in October 2020 during the COVID-19 pandemic. Results: We report the observation of a 16-year-old girl, who received symptomatic outpatient treatment for influenza-like illness with a fever of 38.5°C before rapidly evolving in 1 week to stage E pancreatitis, where a SARS-COV2 IgG and IgM viral serology was requested coming back positive with a negative nasopharyngeal PCR covid. Conclusion: In conclusion, pancreatitis caused by SARS-CoV-2 is a real but rare entity; in fact COVID-19 can present as pancreatitis. This case highlights acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. This diagnosis is important for adequate treatment and better management of systemic repercussions, such as SIRS, decreasing SARS-CoV-2 mortality.},
 year = {2021}
}

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TY  - JOUR
T1  - An Emerging Clinical Form of Acute Pancreatitis in Covid-19
AU  - Meriem Atrassi
AU  - Karima Ryouni
AU  - Dalal Ben Sabbahia
AU  - Abdelhak Abkari
Y1  - 2021/08/04
PY  - 2021
N1  - https://doi.org/10.11648/j.ijg.20210502.13
DO  - 10.11648/j.ijg.20210502.13
T2  - International Journal of Gastroenterology
JF  - International Journal of Gastroenterology
JO  - International Journal of Gastroenterology
SP  - 53
EP  - 56
PB  - Science Publishing Group
SN  - 2640-169X
UR  - https://doi.org/10.11648/j.ijg.20210502.13
AB  - Background: As the global severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic continues, new clinical forms of the disease continue to emerge. While the coronavirus is responsible for gastrointestinal symptoms and acute hepatitis, researchers at the Royal University Hospital of Liverpool say they have identified cases of COVID-19-linked pancreatitis in young patients with COVID-19. Objectives: To establish influence of concomitant COVID-19 on clinical presentation and treatment strategy of patients with AP. Methods: This is a case report of pediatric patient admitted to a Pediatric Gastroenterology Unit, A. Harouchi Hospital, CHU Ibn Rochd, Casablanca, Morocco in October 2020 during the COVID-19 pandemic. Results: We report the observation of a 16-year-old girl, who received symptomatic outpatient treatment for influenza-like illness with a fever of 38.5°C before rapidly evolving in 1 week to stage E pancreatitis, where a SARS-COV2 IgG and IgM viral serology was requested coming back positive with a negative nasopharyngeal PCR covid. Conclusion: In conclusion, pancreatitis caused by SARS-CoV-2 is a real but rare entity; in fact COVID-19 can present as pancreatitis. This case highlights acute pancreatitis as a complication associated with COVID-19 and underlines the importance of measuring pancreas-specific plasma amylase in patients with COVID-19 and abdominal pain. This diagnosis is important for adequate treatment and better management of systemic repercussions, such as SIRS, decreasing SARS-CoV-2 mortality.
VL  - 5
IS  - 2
ER  -

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