Cancer Research Journal

Volume 4, Issue 5, September 2016

  • Perfusion of Multiple Micronutrients Supplement of HCC-Invaded Human Liver Reduces Oxidative Stress and Proliferation of Cancer Cells

    Torricelli Piera, Ferorelli Pasquale, Shevchenko Anna, Antonelli Francesco, Siciliano Alberto, De Martino Angelo, Beninati Simone

    Issue: Volume 4, Issue 5, September 2016
    Pages: 69-72
    Received: 4 August 2016
    Accepted: 26 August 2016
    Published: 21 September 2016
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    Abstract: Administration of the chemotherapeutic agent by organ perfusion is more effective than the systemic administration. The active drug is reached by the tumor, to a higher concentration, and normal tissues are spared from major damages. The perfusion of various areas of the body is a recent goal of the experimental and clinical trials. Fatal malignanc... Show More
  • Copper Enhances Antitumor Activity of Water Soluble Garlic Extract Components on a Human Hepatoma Cell Line

    Angelo De Martino, Hanan Mahmoud Abu-Zeid, Piera Torricelli, Anna Shevchenko, Alberto Siciliano, Simone Beninati

    Issue: Volume 4, Issue 5, September 2016
    Pages: 73-83
    Received: 3 August 2016
    Accepted: 31 August 2016
    Published: 21 September 2016
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    Abstract: Water garlic extract combined with Copper (GE-Cu) shows specific anti-proliferative and antitumoral activity in human hepatocarcinoma (HepG2) cancer cell line, while it is not active on differentiated or primary isolated cells, normal human dermal fibroblasts (HDF) and human epidermal keratinocytes (HEK). Since other transition metals do not affect... Show More