Prevalence of Hepatitis B Virus Infection Among Patients with Chronic Kidney Disease in Jos University Teaching Hospital (JUTH) Jos, Nigeria
Jude Yunzoom Nkup,
Prisca Ofoeke,
Julius Ocheme Okojokwu,
Otobo Innocent Ujah,
Emeka Ubah Ejeliogu,
Joseph Aje Anejo-Okopi
Issue:
Volume 3, Issue 1, January 2018
Pages:
1-5
Received:
23 September 2017
Accepted:
16 October 2017
Published:
5 December 2017
Abstract: The frequency of hepatitis B virus in patients with CKD undergoing haemodialysis maintenance has a medical importance in the transmission of the infection and the cause of kidney disease. We aimed to determine sero-prevalence of HBV in patients with chronic kidney disease. A total of 110 blood samples were collected from nephrology Department of Jos University Teaching Hospital and screened for HBsAg marker. HBsAg was detected using rapid chromatographic immunoassays for qualitative detection of HBsAg and was performed using one-step test strips for detection of HBsAg in serum sample. Out of the 110 patients selected, 56 were males and 54 females with an overall 15.5% HBsAg positivity. It was observed that HBsAg positive increases with prolonged duration of haemodialysis maintenance. The prevalence of HBsAg among Chronic Kidney Disease patients is high, however there was no significant association between HBV and chronic kidney disease in this cross-Sectional survey.
Abstract: The frequency of hepatitis B virus in patients with CKD undergoing haemodialysis maintenance has a medical importance in the transmission of the infection and the cause of kidney disease. We aimed to determine sero-prevalence of HBV in patients with chronic kidney disease. A total of 110 blood samples were collected from nephrology Department of Jo...
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Protective Effect of Antrodia Camphorate on the Tissues of Brain, Kidney, Lung, and Liver Is Correlated with Declining Lipid Peroxidation
Mei-Min Shiu,
Bo-Yu Huang,
Chien-Chi Liu,
Chin-Sheng Liao,
Ming-Cheng Lin
Issue:
Volume 3, Issue 1, January 2018
Pages:
6-10
Received:
23 September 2017
Accepted:
16 October 2017
Published:
14 December 2017
Abstract: Previous investigation has proposed that Antrodia Camphorata possesses beneficial effect mainly on liver protection. To date, the antioxidative effect of Antrodia Camphorata on the tissues of brain, kidney, lung, and liver, however, has not yet clarified. In this current experiment, eighty male Sprague-Dawley rats were randomly divided into control and Antrodia Camphorate-treated subject. Both subjects were intraperitoneally injected with normal saline and Antrodia Camphorata for consecutive 14 days, respectively. On day 15, rats were sacrificed and tissues of brain, kidney, lung, and liver were immediately harvested and homogenate. The malondialdehyde level, an end-product of lipid peroxidation, was measured in different tissues. Experimental result showed that the malondialdehyde levels were significantly (P < 0.05) reduced in all tissues after receiving Antrodia Camphorate as compared with the control subject. Specifically, an obvious decline (12.93%) of the malondialdehyde level was found in the brain as compared to the tissues of kidney, lung, and liver. Accordingly, our present result indicates that Antrodia Camphorate can significantly decline oxidative damage as presented by a reduced malondialdehyde levels in the tissues of brain, kidney, lung, and liver. In addition, it seems likely that the best tissue protective efficacy offered by Antrodia Camphorate in declining oxidative damage is found in the brain tissue.
Abstract: Previous investigation has proposed that Antrodia Camphorata possesses beneficial effect mainly on liver protection. To date, the antioxidative effect of Antrodia Camphorata on the tissues of brain, kidney, lung, and liver, however, has not yet clarified. In this current experiment, eighty male Sprague-Dawley rats were randomly divided into control...
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Improved Metabolism of Vitamin D3 in Human Osteoblasts Cells After Biofield Energy Healing Treatment
Vaibhav Rajan Parulkar,
Mahendra Kumar Trivedi,
Alice Branton,
Dahryn Trivedi,
Gopal Nayak,
Mayank Gangwar,
Snehasis Jana
Issue:
Volume 3, Issue 1, January 2018
Pages:
11-19
Received:
4 December 2017
Accepted:
13 December 2017
Published:
12 January 2018
Abstract: Bone formation, remodeling, mineralization, resorption, and healing processes involves a coordinated action of different cell types, which are very prevalent in the elderly population. The current study aimed to evaluate the potential of Consciousness Energy Healing based vitamin D3 and DMEM medium on bone health. Vitamin D3 and DMEM medium as test items (TI), were divided into two parts. One part of each sample received the Consciousness Energy Healing Treatment by Vaibhav Rajan Parulkar and those samples were labeled as the Biofield Energy Treated (BT) samples, while the other parts of each sample were denoted as the untreated test items (UT). Bone health biomarkers such as alkaline phosphatase enzyme (ALP) activity, collagen levels and bone mineralization were studied. The cell viability using MTT assay showed that the test items were found to be safe. ALP level was significantly increased by 304.6%, 237.2%, and 110.6% at 1, 10, and 50 µg/mL, respectively in BT-DMEM+UT-TI, while 356.9%, 186.2%, and 87.3% at 1, 10, and 50 µg/mL, respectively in the BT-DMEM+BT-TI group as compared to the untreated group. Collagen content was significantly increased up to 163.7%, 114.4%, and 22.7% at 0.1, 1, and 10 µg/mL, respectively in the UT-DMEM+BT-TI group, while 190.1%, 64.9%, and 50% increased collagen at 0.1, 1, and 10 µg/mL, respectively in the BT-DMEM+BT-TI group as compared with the untreated group. Moreover, the percent of bone mineralization was significantly increased by 330% and 121.5% at 0.1 and 1 µg/mL, respectively in the BT-DMEM+BT-TI group, while 146.7% and 305.9% at 0.1 and 1 µg/mL, respectively in the BT-DMEM+UT-TI group, as compared with the untreated group. In conclusion, the Biofield Energy Treated vitamin D3 and DMEM would play an important role to control the osteoblast function, improves bone mineralization, and calcium absorption in many bone disorders. Moreover, the bone health parameters such as collagen, calcium, and ALP were significantly improved and can be used as supplement to improve bone health. Based on the outstanding results, it is assumed that the Biofield Energy Treated vitamin D3 could be a powerful alternative dietary sources and supplements to fight against various bone related diseases including low bone density and osteoporosis, Paget’s disease of bone, rickets, deformed bones, osteomalacia, bone and/or joint pain, increased frequency of fractures, osteoma, hormonal imbalance, stress, aging, bone loss and fractures.
Abstract: Bone formation, remodeling, mineralization, resorption, and healing processes involves a coordinated action of different cell types, which are very prevalent in the elderly population. The current study aimed to evaluate the potential of Consciousness Energy Healing based vitamin D3 and DMEM medium on bone health. Vitamin D3 and DMEM medium as test...
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Pulmonary and Rifampicin-Resistant Tuberculosis Associated with Human Immunodeficiency Virus Infection Prevalence in Bayelsa State, Nigeria: A Case of Patients Attending Federal Medical Centre Yenagoa
Nsikak Godwin Etim,
Frankland Oyeins Briyai
Issue:
Volume 3, Issue 1, January 2018
Pages:
20-24
Received:
18 September 2017
Accepted:
26 September 2017
Published:
16 January 2018
Abstract: This study investigated the prevalence of pulmonary tuberculosis (PTB) associated human immunodeficiency virus/ acquired immunodeficiency syndrome (HIV/AIDs) infection among patients attending Federal Medical Centre Yenagoa, Bayelsa state, Nigeria. Out of the 456 subjects recruited for the study, 88 patients (comprising of male and females) with known cases of PTB was studied for the association of HIV with PTB. Blood and sputum samples were collected following standard procedure. HIV/AIDS was determined following serial all logarithm test viz: Determine, Unigold, Stat pack, while the PTB and rifampicin resistant tuberculosis (RMPR – TB) was analyzed using GeneXpert System. Results showed that 41(9.0%) and 47 (10.3%) was seropositive and seronegative to HIV/AIDS. There was no significant difference (P>0.01) among the serotypes/groups. Also 0.7% of the PTB subjects with HIV were resistant to rifampicin. Therefore, there is the need for surveillance of drug resistance in tuberculosis which could lead strengthening of laboratory networks and enhance its prevention and control.
Abstract: This study investigated the prevalence of pulmonary tuberculosis (PTB) associated human immunodeficiency virus/ acquired immunodeficiency syndrome (HIV/AIDs) infection among patients attending Federal Medical Centre Yenagoa, Bayelsa state, Nigeria. Out of the 456 subjects recruited for the study, 88 patients (comprising of male and females) with kn...
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