Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study

Esan Ayodele Jacob

doi:doi:10.11648/j.ajlm.20160103.12

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Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study

Esan Ayodele Jacob

Published in American Journal of Laboratory Medicine (Volume 1, Issue 3)

Received: 10 September 2016 Accepted: 1 October 2016 Published: 29 November 2016

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Abstract

The aim of this review is to assist non-hematologist effective means of interpreting complete blood cell (CBC) counts results especially when encountered with abnormal result for intellectually rewarding practice and to recognize when a subspecialty consultation is reasonable and when it may be circumvented. A complete blood cell count is routine hematology tests in medicine useful for the differential diagnosis of anemia and other medical conditions. A good percentage of CBC results are reported as abnormal, therefore it is in every clinician’s interest to have some understanding of the specific test basics as well as a structured action plan when confronted with abnormal results. It is a series of tests used to evaluate the composition and concentration of the cellular components of blood, which consists: red blood cell (RBC) counts, red cell indices, hematocrit, hemoglobin concentration, white blood cell (WBC) count, classification of white blood cells (WBC differential) and platelet count. CBC provides valuable information about the blood and to some extent the bone marrow, which is the blood-forming tissue. CBC can be use for the following purposes: as a preoperative test to ensure both adequate oxygen carrying capacity and hemostasis, to identify acute and chronic illness, bleeding tendencies, and white blood cell disorders such as leukemia, to monitor a medical condition and changes in the body system caused by medical treatments, to determine the effects of chemotherapy and radiation therapy on blood cell production. CBC can be performed manually using visual examination or automation by fluorescence flow cytometry and impedance. In conclusion, CBC and peripheral blood examination are one of the most commonly ordered tests that provides important information about the kinds and numbers of cells in the blood, abnormalities in any of these types of blood cells may indicate the presence of important medical disorders.

Published in	American Journal of Laboratory Medicine (Volume 1, Issue 3)
DOI	10.11648/j.ajlm.20160103.12
Page(s)	34-57
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Blood Cells, Complete Blood Cell Count, Peripheral Blood Film

References

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Esan Ayodele Jacob. (2016). Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. American Journal of Laboratory Medicine, 1(3), 34-57. https://doi.org/10.11648/j.ajlm.20160103.12

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Esan Ayodele Jacob. Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. Am. J. Lab. Med. 2016, 1(3), 34-57. doi: 10.11648/j.ajlm.20160103.12

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AMA Style

Esan Ayodele Jacob. Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. Am J Lab Med. 2016;1(3):34-57. doi: 10.11648/j.ajlm.20160103.12

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@article{10.11648/j.ajlm.20160103.12,
  author = {Esan Ayodele Jacob},
  title = {Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study},
  journal = {American Journal of Laboratory Medicine},
  volume = {1},
  number = {3},
  pages = {34-57},
  doi = {10.11648/j.ajlm.20160103.12},
  url = {https://doi.org/10.11648/j.ajlm.20160103.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20160103.12},
  abstract = {The aim of this review is to assist non-hematologist effective means of interpreting complete blood cell (CBC) counts results especially when encountered with abnormal result for intellectually rewarding practice and to recognize when a subspecialty consultation is reasonable and when it may be circumvented. A complete blood cell count is routine hematology tests in medicine useful for the differential diagnosis of anemia and other medical conditions. A good percentage of CBC results are reported as abnormal, therefore it is in every clinician’s interest to have some understanding of the specific test basics as well as a structured action plan when confronted with abnormal results. It is a series of tests used to evaluate the composition and concentration of the cellular components of blood, which consists: red blood cell (RBC) counts, red cell indices, hematocrit, hemoglobin concentration, white blood cell (WBC) count, classification of white blood cells (WBC differential) and platelet count. CBC provides valuable information about the blood and to some extent the bone marrow, which is the blood-forming tissue. CBC can be use for the following purposes: as a preoperative test to ensure both adequate oxygen carrying capacity and hemostasis, to identify acute and chronic illness, bleeding tendencies, and white blood cell disorders such as leukemia, to monitor a medical condition and changes in the body system caused by medical treatments, to determine the effects of chemotherapy and radiation therapy on blood cell production. CBC can be performed manually using visual examination or automation by fluorescence flow cytometry and impedance. In conclusion, CBC and peripheral blood examination are one of the most commonly ordered tests that provides important information about the kinds and numbers of cells in the blood, abnormalities in any of these types of blood cells may indicate the presence of important medical disorders.},
 year = {2016}
}

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TY  - JOUR
T1  - Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study
AU  - Esan Ayodele Jacob
Y1  - 2016/11/29
PY  - 2016
N1  - https://doi.org/10.11648/j.ajlm.20160103.12
DO  - 10.11648/j.ajlm.20160103.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 34
EP  - 57
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20160103.12
AB  - The aim of this review is to assist non-hematologist effective means of interpreting complete blood cell (CBC) counts results especially when encountered with abnormal result for intellectually rewarding practice and to recognize when a subspecialty consultation is reasonable and when it may be circumvented. A complete blood cell count is routine hematology tests in medicine useful for the differential diagnosis of anemia and other medical conditions. A good percentage of CBC results are reported as abnormal, therefore it is in every clinician’s interest to have some understanding of the specific test basics as well as a structured action plan when confronted with abnormal results. It is a series of tests used to evaluate the composition and concentration of the cellular components of blood, which consists: red blood cell (RBC) counts, red cell indices, hematocrit, hemoglobin concentration, white blood cell (WBC) count, classification of white blood cells (WBC differential) and platelet count. CBC provides valuable information about the blood and to some extent the bone marrow, which is the blood-forming tissue. CBC can be use for the following purposes: as a preoperative test to ensure both adequate oxygen carrying capacity and hemostasis, to identify acute and chronic illness, bleeding tendencies, and white blood cell disorders such as leukemia, to monitor a medical condition and changes in the body system caused by medical treatments, to determine the effects of chemotherapy and radiation therapy on blood cell production. CBC can be performed manually using visual examination or automation by fluorescence flow cytometry and impedance. In conclusion, CBC and peripheral blood examination are one of the most commonly ordered tests that provides important information about the kinds and numbers of cells in the blood, abnormalities in any of these types of blood cells may indicate the presence of important medical disorders.
VL  - 1
IS  - 3
ER  -

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Author Information

Esan Ayodele Jacob

Department of Hematology and Blood transfusion, Federal Teaching Hospital, Ido-Ekiti, Nigeria

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Esan Ayodele Jacob. (2016). Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. American Journal of Laboratory Medicine, 1(3), 34-57. https://doi.org/10.11648/j.ajlm.20160103.12

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ACS Style

Esan Ayodele Jacob. Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. Am. J. Lab. Med. 2016, 1(3), 34-57. doi: 10.11648/j.ajlm.20160103.12

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AMA Style

Esan Ayodele Jacob. Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study. Am J Lab Med. 2016;1(3):34-57. doi: 10.11648/j.ajlm.20160103.12

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@article{10.11648/j.ajlm.20160103.12,
  author = {Esan Ayodele Jacob},
  title = {Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study},
  journal = {American Journal of Laboratory Medicine},
  volume = {1},
  number = {3},
  pages = {34-57},
  doi = {10.11648/j.ajlm.20160103.12},
  url = {https://doi.org/10.11648/j.ajlm.20160103.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20160103.12},
  abstract = {The aim of this review is to assist non-hematologist effective means of interpreting complete blood cell (CBC) counts results especially when encountered with abnormal result for intellectually rewarding practice and to recognize when a subspecialty consultation is reasonable and when it may be circumvented. A complete blood cell count is routine hematology tests in medicine useful for the differential diagnosis of anemia and other medical conditions. A good percentage of CBC results are reported as abnormal, therefore it is in every clinician’s interest to have some understanding of the specific test basics as well as a structured action plan when confronted with abnormal results. It is a series of tests used to evaluate the composition and concentration of the cellular components of blood, which consists: red blood cell (RBC) counts, red cell indices, hematocrit, hemoglobin concentration, white blood cell (WBC) count, classification of white blood cells (WBC differential) and platelet count. CBC provides valuable information about the blood and to some extent the bone marrow, which is the blood-forming tissue. CBC can be use for the following purposes: as a preoperative test to ensure both adequate oxygen carrying capacity and hemostasis, to identify acute and chronic illness, bleeding tendencies, and white blood cell disorders such as leukemia, to monitor a medical condition and changes in the body system caused by medical treatments, to determine the effects of chemotherapy and radiation therapy on blood cell production. CBC can be performed manually using visual examination or automation by fluorescence flow cytometry and impedance. In conclusion, CBC and peripheral blood examination are one of the most commonly ordered tests that provides important information about the kinds and numbers of cells in the blood, abnormalities in any of these types of blood cells may indicate the presence of important medical disorders.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Complete Blood Cell Count and Peripheral Blood Film, Its Significant in Laboratory Medicine: A Review Study
AU  - Esan Ayodele Jacob
Y1  - 2016/11/29
PY  - 2016
N1  - https://doi.org/10.11648/j.ajlm.20160103.12
DO  - 10.11648/j.ajlm.20160103.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 34
EP  - 57
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20160103.12
AB  - The aim of this review is to assist non-hematologist effective means of interpreting complete blood cell (CBC) counts results especially when encountered with abnormal result for intellectually rewarding practice and to recognize when a subspecialty consultation is reasonable and when it may be circumvented. A complete blood cell count is routine hematology tests in medicine useful for the differential diagnosis of anemia and other medical conditions. A good percentage of CBC results are reported as abnormal, therefore it is in every clinician’s interest to have some understanding of the specific test basics as well as a structured action plan when confronted with abnormal results. It is a series of tests used to evaluate the composition and concentration of the cellular components of blood, which consists: red blood cell (RBC) counts, red cell indices, hematocrit, hemoglobin concentration, white blood cell (WBC) count, classification of white blood cells (WBC differential) and platelet count. CBC provides valuable information about the blood and to some extent the bone marrow, which is the blood-forming tissue. CBC can be use for the following purposes: as a preoperative test to ensure both adequate oxygen carrying capacity and hemostasis, to identify acute and chronic illness, bleeding tendencies, and white blood cell disorders such as leukemia, to monitor a medical condition and changes in the body system caused by medical treatments, to determine the effects of chemotherapy and radiation therapy on blood cell production. CBC can be performed manually using visual examination or automation by fluorescence flow cytometry and impedance. In conclusion, CBC and peripheral blood examination are one of the most commonly ordered tests that provides important information about the kinds and numbers of cells in the blood, abnormalities in any of these types of blood cells may indicate the presence of important medical disorders.
VL  - 1
IS  - 3
ER  -

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