American Journal of Laboratory Medicine

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Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach

Received: Jan. 16, 2019    Accepted: Feb. 19, 2019    Published: Mar. 18, 2019
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Abstract

Asymptomatic bacteriuria is the presence of multiplying bacteria in the absence of any symptoms. The relevance of ASB lies in the insight it provides into symptomatic infections. Physiological and anatomical alterations during pregnancy make women more predisposed to urinary tract infection. This study seeks to determine the prevalence, risk factors, and bacteria profile among pregnant and non-pregnant women. A total of 230 pregnant women and 100 age-matched non-pregnant women were recruited. All pregnant women were recruited from individuals attending antenatal clinic and the controls recruited within the same hospital. Clean catch mid-stream urines ample was collected and microbial analysis done immediately. Significant ASB was identified and antibiotic sensitivity determined by conventional protocols. The overall prevalence of ASB in this study was 29.1% and 15% among pregnant and non-pregnant women respectively. The mean age was 25.3±5.2 and 24.2±5.6years for pregnant and non-pregnant women. Based on their parity among pregnant women, 112 (48.7%), 61(26.5%) and 57 (24.8%) were nulliparous, monoparous and multiparous respectively. Also, 37(16.1%), 70(30.4%) and 123(53.5%) of the pregnant women were in the 1st, 2nd and 3rd trimester. Sixty-seven (29.1%), 125 (54.3%) and 37 (16.1%) pregnant subjects were housewives, self-employed and civil servants in their occupation. Trimester was a risk factor for asymptomatic bacteriuria in the 2nd and 3rd trimester. There was association between age, parity, trimester and ASB. The most common isolate in this study was Escherichia coli (28.4%), followed by Klebsiella pneumonia (23.9%). The Escherichia coli and other uropathogens isolates were multiple drug sensitive between 50-100%. Previous bacteriuria treatment seeking pattern among the pregnant women was 138(60%), 42(18.3%), 32(13.9%) and 1(0.4%) for individuals who had sought treatments in hospitals, patent drug dealers (chemists), multi-centres and traditionally respectively. It is recommended that routine urine culture screening be conducted for all pregnant women at least in the second and third trimesters and positive ASB promptly treated.

DOI 10.11648/j.ajlm.20190401.11
Published in American Journal of Laboratory Medicine ( Volume 4, Issue 1, January 2019 )
Page(s) 1-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Asymptomatic Bacteriuria, Prevalence, Uropathogens, Pregnant Women, Offot Ukwa District

References
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Cite This Article
  • APA Style

    Nseobong Godwin Akpan, Anthony John Umoyen, Thomas Tentishe Luka, Ifeanyi Abraham Onwuezobe, Ukponobong Effiong Antia, et al. (2019). Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach. American Journal of Laboratory Medicine, 4(1), 1-10. https://doi.org/10.11648/j.ajlm.20190401.11

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    ACS Style

    Nseobong Godwin Akpan; Anthony John Umoyen; Thomas Tentishe Luka; Ifeanyi Abraham Onwuezobe; Ukponobong Effiong Antia, et al. Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach. Am. J. Lab. Med. 2019, 4(1), 1-10. doi: 10.11648/j.ajlm.20190401.11

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    AMA Style

    Nseobong Godwin Akpan, Anthony John Umoyen, Thomas Tentishe Luka, Ifeanyi Abraham Onwuezobe, Ukponobong Effiong Antia, et al. Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach. Am J Lab Med. 2019;4(1):1-10. doi: 10.11648/j.ajlm.20190401.11

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  • @article{10.11648/j.ajlm.20190401.11,
      author = {Nseobong Godwin Akpan and Anthony John Umoyen and Thomas Tentishe Luka and Ifeanyi Abraham Onwuezobe and Ukponobong Effiong Antia and Abraham Solomon Okon},
      title = {Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach},
      journal = {American Journal of Laboratory Medicine},
      volume = {4},
      number = {1},
      pages = {1-10},
      doi = {10.11648/j.ajlm.20190401.11},
      url = {https://doi.org/10.11648/j.ajlm.20190401.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajlm.20190401.11},
      abstract = {Asymptomatic bacteriuria is the presence of multiplying bacteria in the absence of any symptoms. The relevance of ASB lies in the insight it provides into symptomatic infections. Physiological and anatomical alterations during pregnancy make women more predisposed to urinary tract infection. This study seeks to determine the prevalence, risk factors, and bacteria profile among pregnant and non-pregnant women. A total of 230 pregnant women and 100 age-matched non-pregnant women were recruited. All pregnant women were recruited from individuals attending antenatal clinic and the controls recruited within the same hospital. Clean catch mid-stream urines ample was collected and microbial analysis done immediately. Significant ASB was identified and antibiotic sensitivity determined by conventional protocols. The overall prevalence of ASB in this study was 29.1% and 15% among pregnant and non-pregnant women respectively. The mean age was 25.3±5.2 and 24.2±5.6years for pregnant and non-pregnant women. Based on their parity among pregnant women, 112 (48.7%), 61(26.5%) and 57 (24.8%) were nulliparous, monoparous and multiparous respectively. Also, 37(16.1%), 70(30.4%) and 123(53.5%) of the pregnant women were in the 1st, 2nd and 3rd trimester. Sixty-seven (29.1%), 125 (54.3%) and 37 (16.1%) pregnant subjects were housewives, self-employed and civil servants in their occupation. Trimester was a risk factor for asymptomatic bacteriuria in the 2nd and 3rd trimester. There was association between age, parity, trimester and ASB. The most common isolate in this study was Escherichia coli (28.4%), followed by Klebsiella pneumonia (23.9%). The Escherichia coli and other uropathogens isolates were multiple drug sensitive between 50-100%. Previous bacteriuria treatment seeking pattern among the pregnant women was 138(60%), 42(18.3%), 32(13.9%) and 1(0.4%) for individuals who had sought treatments in hospitals, patent drug dealers (chemists), multi-centres and traditionally respectively. It is recommended that routine urine culture screening be conducted for all pregnant women at least in the second and third trimesters and positive ASB promptly treated.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Asymptomatic Uropathogenic Bacteriuria Among Pregnant and Non-pregnant Women at St Luke’s Hospital Anua, Offot Ukwa District Uyo: A Reassessment Case-Control Approach
    AU  - Nseobong Godwin Akpan
    AU  - Anthony John Umoyen
    AU  - Thomas Tentishe Luka
    AU  - Ifeanyi Abraham Onwuezobe
    AU  - Ukponobong Effiong Antia
    AU  - Abraham Solomon Okon
    Y1  - 2019/03/18
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajlm.20190401.11
    DO  - 10.11648/j.ajlm.20190401.11
    T2  - American Journal of Laboratory Medicine
    JF  - American Journal of Laboratory Medicine
    JO  - American Journal of Laboratory Medicine
    SP  - 1
    EP  - 10
    PB  - Science Publishing Group
    SN  - 2575-386X
    UR  - https://doi.org/10.11648/j.ajlm.20190401.11
    AB  - Asymptomatic bacteriuria is the presence of multiplying bacteria in the absence of any symptoms. The relevance of ASB lies in the insight it provides into symptomatic infections. Physiological and anatomical alterations during pregnancy make women more predisposed to urinary tract infection. This study seeks to determine the prevalence, risk factors, and bacteria profile among pregnant and non-pregnant women. A total of 230 pregnant women and 100 age-matched non-pregnant women were recruited. All pregnant women were recruited from individuals attending antenatal clinic and the controls recruited within the same hospital. Clean catch mid-stream urines ample was collected and microbial analysis done immediately. Significant ASB was identified and antibiotic sensitivity determined by conventional protocols. The overall prevalence of ASB in this study was 29.1% and 15% among pregnant and non-pregnant women respectively. The mean age was 25.3±5.2 and 24.2±5.6years for pregnant and non-pregnant women. Based on their parity among pregnant women, 112 (48.7%), 61(26.5%) and 57 (24.8%) were nulliparous, monoparous and multiparous respectively. Also, 37(16.1%), 70(30.4%) and 123(53.5%) of the pregnant women were in the 1st, 2nd and 3rd trimester. Sixty-seven (29.1%), 125 (54.3%) and 37 (16.1%) pregnant subjects were housewives, self-employed and civil servants in their occupation. Trimester was a risk factor for asymptomatic bacteriuria in the 2nd and 3rd trimester. There was association between age, parity, trimester and ASB. The most common isolate in this study was Escherichia coli (28.4%), followed by Klebsiella pneumonia (23.9%). The Escherichia coli and other uropathogens isolates were multiple drug sensitive between 50-100%. Previous bacteriuria treatment seeking pattern among the pregnant women was 138(60%), 42(18.3%), 32(13.9%) and 1(0.4%) for individuals who had sought treatments in hospitals, patent drug dealers (chemists), multi-centres and traditionally respectively. It is recommended that routine urine culture screening be conducted for all pregnant women at least in the second and third trimesters and positive ASB promptly treated.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, University of Uyo, Uyo, Nigeria; Medical Microbiology Unit, Department of Medical Laboratory Science, Faculty of Allied Medical Sciences, University of Calabar, Calabar, Nigeria

  • Department of Genetics and Biotechnology, Faculty of Biological Sciences, University of Calabar, Calabar, Nigeria

  • Department of Biological Sciences, Taraba State University, Jalingo, Nigeria

  • Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, University of Uyo Teaching Hospital, Uyo, Nigeria

  • Department of Biological Sciences, Akwa Ibom State University, Mkpat Enin, Nigeria

  • Department of Genetics and Biotechnology, Faculty of Biological Sciences, University of Calabar, Calabar, Nigeria

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