American Journal of Laboratory Medicine

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Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria

Received: Aug. 18, 2019    Accepted: Sep. 19, 2019    Published: Dec. 17, 2019
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Abstract

Brain tumours are diverse group of primary CNS tumours and secondary neoplasm arising either from the scalp or from haematogenous spread from distant sites with few biologically aggressive tumours in both adult and paediatric age groups. Brain tumours have been classified based on their presumed cell of origin and degree of differentiation as determined by light microscopy and immunohistochemical studies with tumours distinctive tumour biology, treatment and prognosis. A retrospective study of all cases of intracranial tumours seen over a period of 10 years from January 2008 to December 2017 at Department of Pathology, Usmanu Danfodiyo University Teaching Hospital. This is a regional neurosurgical centre situated at Sokoto North-West Nigeria receiving surgical specimens from Birnin Kebbi, Zamfara, Sokoto, and Katsina state. The age, sex, histologic diagnosis, and histologic grading system using the 2007 WHO grading system were retrieved and recorded. This study reviewed 151 patients managed with histology confirmed intracranial tumour (ICTs). Mean age was 28.17 ±17.26 years. The male-to-female ratio was 1.6:1.0. Peak age range was the third decade (21-30years) and accounted for (20.5%). Primary ICTs accounted for 95.4% of the cases and metastatic adenocarcinomas accounted for 4.6% of the diagnoses and all the cases were seen in adults. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3%. The mean age of meningioma was 32±11.9 years with age range from 3 – 58years and male to female ratio of 1.4:1 and WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3% with WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11.

DOI 10.11648/j.ajlm.20190406.17
Published in American Journal of Laboratory Medicine ( Volume 4, Issue 6, November 2019 )
Page(s) 119-123
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Histopathological Pattern, Intracranial Tumour, Meningioma, Glioma, Embryonal Tumours

References
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[8] Idowu O, Akang E, Malomo A. Symptomatic primary intracranial neoplasm in Nigeria. West Afri. J NeurolSci (Turk) 2007; 19 (24): 212-218.
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  • APA Style

    Sahabi Sadiku Malami, Rasheed Mumini Wemimo, Abdullahi Kabiru, Adegboye Adeyemi Taiwo, Mohammed Umar, et al. (2019). Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria. American Journal of Laboratory Medicine, 4(6), 119-123. https://doi.org/10.11648/j.ajlm.20190406.17

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    ACS Style

    Sahabi Sadiku Malami; Rasheed Mumini Wemimo; Abdullahi Kabiru; Adegboye Adeyemi Taiwo; Mohammed Umar, et al. Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria. Am. J. Lab. Med. 2019, 4(6), 119-123. doi: 10.11648/j.ajlm.20190406.17

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    AMA Style

    Sahabi Sadiku Malami, Rasheed Mumini Wemimo, Abdullahi Kabiru, Adegboye Adeyemi Taiwo, Mohammed Umar, et al. Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria. Am J Lab Med. 2019;4(6):119-123. doi: 10.11648/j.ajlm.20190406.17

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  • @article{10.11648/j.ajlm.20190406.17,
      author = {Sahabi Sadiku Malami and Rasheed Mumini Wemimo and Abdullahi Kabiru and Adegboye Adeyemi Taiwo and Mohammed Umar and Afolayan Enoch Abiodun and Oluogun Waheed Akanni and Mohammad Shareef Bello and Nasiru Jinjiri Ismail},
      title = {Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria},
      journal = {American Journal of Laboratory Medicine},
      volume = {4},
      number = {6},
      pages = {119-123},
      doi = {10.11648/j.ajlm.20190406.17},
      url = {https://doi.org/10.11648/j.ajlm.20190406.17},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajlm.20190406.17},
      abstract = {Brain tumours are diverse group of primary CNS tumours and secondary neoplasm arising either from the scalp or from haematogenous spread from distant sites with few biologically aggressive tumours in both adult and paediatric age groups. Brain tumours have been classified based on their presumed cell of origin and degree of differentiation as determined by light microscopy and immunohistochemical studies with tumours distinctive tumour biology, treatment and prognosis. A retrospective study of all cases of intracranial tumours seen over a period of 10 years from January 2008 to December 2017 at Department of Pathology, Usmanu Danfodiyo University Teaching Hospital. This is a regional neurosurgical centre situated at Sokoto North-West Nigeria receiving surgical specimens from Birnin Kebbi, Zamfara, Sokoto, and Katsina state. The age, sex, histologic diagnosis, and histologic grading system using the 2007 WHO grading system were retrieved and recorded. This study reviewed 151 patients managed with histology confirmed intracranial tumour (ICTs). Mean age was 28.17 ±17.26 years. The male-to-female ratio was 1.6:1.0. Peak age range was the third decade (21-30years) and accounted for (20.5%). Primary ICTs accounted for 95.4% of the cases and metastatic adenocarcinomas accounted for 4.6% of the diagnoses and all the cases were seen in adults. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3%. The mean age of meningioma was 32±11.9 years with age range from 3 – 58years and male to female ratio of 1.4:1 and WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3% with WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11.},
     year = {2019}
    }
    

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    T1  - Histopathological Patterns of Intracranial Tumours at a Tertiary Health Facility in Sokoto, North-West Nigeria
    AU  - Sahabi Sadiku Malami
    AU  - Rasheed Mumini Wemimo
    AU  - Abdullahi Kabiru
    AU  - Adegboye Adeyemi Taiwo
    AU  - Mohammed Umar
    AU  - Afolayan Enoch Abiodun
    AU  - Oluogun Waheed Akanni
    AU  - Mohammad Shareef Bello
    AU  - Nasiru Jinjiri Ismail
    Y1  - 2019/12/17
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    N1  - https://doi.org/10.11648/j.ajlm.20190406.17
    DO  - 10.11648/j.ajlm.20190406.17
    T2  - American Journal of Laboratory Medicine
    JF  - American Journal of Laboratory Medicine
    JO  - American Journal of Laboratory Medicine
    SP  - 119
    EP  - 123
    PB  - Science Publishing Group
    SN  - 2575-386X
    UR  - https://doi.org/10.11648/j.ajlm.20190406.17
    AB  - Brain tumours are diverse group of primary CNS tumours and secondary neoplasm arising either from the scalp or from haematogenous spread from distant sites with few biologically aggressive tumours in both adult and paediatric age groups. Brain tumours have been classified based on their presumed cell of origin and degree of differentiation as determined by light microscopy and immunohistochemical studies with tumours distinctive tumour biology, treatment and prognosis. A retrospective study of all cases of intracranial tumours seen over a period of 10 years from January 2008 to December 2017 at Department of Pathology, Usmanu Danfodiyo University Teaching Hospital. This is a regional neurosurgical centre situated at Sokoto North-West Nigeria receiving surgical specimens from Birnin Kebbi, Zamfara, Sokoto, and Katsina state. The age, sex, histologic diagnosis, and histologic grading system using the 2007 WHO grading system were retrieved and recorded. This study reviewed 151 patients managed with histology confirmed intracranial tumour (ICTs). Mean age was 28.17 ±17.26 years. The male-to-female ratio was 1.6:1.0. Peak age range was the third decade (21-30years) and accounted for (20.5%). Primary ICTs accounted for 95.4% of the cases and metastatic adenocarcinomas accounted for 4.6% of the diagnoses and all the cases were seen in adults. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3%. The mean age of meningioma was 32±11.9 years with age range from 3 – 58years and male to female ratio of 1.4:1 and WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11. Meningioma was the most commonly diagnosed intracranial tumours (39.7%), followed by astrocytoma (23.2%), pituitary adenomas (7.3%), craniopharyngioma (11.9%) and nodular medulloblastoma accounted for 4.0%. The most common histologic subtype of meningioma was psammomatous accounted for 75.5%, followed by meningotheliomatous 18.5% and the least was transitional 1.3% with WHO classification of meningioma are stratified into 3; 95% are in grade 1 and 5% are in grade 11.
    VL  - 4
    IS  - 6
    ER  - 

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Author Information
  • Departments of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

  • Department of Histopathology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

  • Departments of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

  • Mojitaiwo Data Services and Data Management Executives, Ilorin, Nigeria

  • Departments of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

  • Department of Histopathology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

  • Departments of Histopathology, Ladoke Akintola University of Technology, Osogho, Nigeria

  • Department of Computer Science, Lead City University, Ibadan, Nigeria

  • Department of Surgery, Usmanu Danfodio University Teaching Hospital, Sokoto, Nigeria

  • Section