HIV/AIDS and Syphilis Sero-prevalence Among Pregnant Women Attending Antenatal Care Center in Rwanda
American Journal of Laboratory Medicine
Volume 5, Issue 4, July 2020, Pages: 83-87
Received: Jun. 30, 2020;
Accepted: Jul. 13, 2020;
Published: Aug. 5, 2020
Views 164 Downloads 56
Nyirahabihirwe Françoise, Department of Biomedical Laboratory Sciences, Faculty of Applied Fundamental Sciences, INES-Ruhengeri, Musanze, Rwanda
Munyemana Jean Bosco, Department of Clinical Biology, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda
Nikuze Bellancille, Department of Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda
Nsabimana Théoneste, Department of Internal Medicine, Kibagabaga District Hospital, Kigali, Rwanda
Sexually transmitted infections pause a global challenge. Mostly, human immunodeficiency virus (HIV) and syphilis which are both transmitted sexually, infect a substantial number of people where female are at front line of exposure and high risk. Additionally, pregnant women experience more vulnerability exposing their infants to increased risk of dying from prematurity, low-birth-weight, stillbirth and congenital diseases. Therefore, continued surveillance of this co-infection is of paramount to establish the status of the diseases and increase the awareness. The current study has evaluated sero-prevalence of HIV and syphilis among pregnant women attending antenatal care center in Rwanda. In total, 1672 pregnant women who visited antenatal care center from 1st/sup> January to 31st/sup> December 2017 were included in the study. First, retrospectively, 1320 patient’s files were reviewed and all HIV and syphilis serological status and demographic characteristics were recorded from 1st/sup> January 2017 to 30th September 2017. Second, prospectively, from 1st/sup> October to 31st/sup> December 2017, 352 participants who accepted to participate in the study, gave blood sample for HIV and syphilis testing. The data were entered in SPSS version 22 and frequencies, percentage and chi-square tests were performed. As results, HIV and syphilis sero-prevalence were 71 (4.2%) and 29 (1.7%) respectively. In addition, 20 (1.2%) had HIV/syphilis co-infection. The cohabitant women exhibited higher HIV/syphilis co- infection than other women. HIV/syphilis co-infection exhibited a statistical significant association P.value 0.000. This finding suggest continued surveillance and special intervention for pregnant women to reduce their increased risk of sexually transmitted infection. In addition, cohabitant women need special intervention to reduce their increased risk of infection.
Munyemana Jean Bosco,
HIV/AIDS and Syphilis Sero-prevalence Among Pregnant Women Attending Antenatal Care Center in Rwanda, American Journal of Laboratory Medicine.
Vol. 5, No. 4,
2020, pp. 83-87.
Paraskevis D, Hatzakis A. Global molecular epidemiology of HIV-1: the chameleon challenge. The Lancet Infectious diseases. 2019 Feb; 19 (2): 114-5. PubMed PMID: 30509776.
Msuya SE, Uriyo J, Hussain A, Mbizvo EM, Jeansson S, Sam NE, et al. Prevalence of sexually transmitted infections among pregnant women with known HIV status in northern Tanzania. Reproductive health. 2009 Feb 25; 6: 4. PubMed PMID: 19243592. Pubmed Central PMCID: 2654873.
East L, Peters K, Jackson D. Violated and vulnerable: women's experiences of contracting a sexually transmitted infection from a male partner. Journal of clinical nursing. 2017 Aug; 26 (15-16): 2342-52. PubMed PMID: 28071836.
Oliffe JL, Chabot C, Knight R, Davis W, Bungay V, Shoveller JA. Women on men's sexual health and sexually transmitted infection testing: a gender relations analysis. Sociology of health & illness. 2013 Jan; 35 (1): 1-16. PubMed PMID: 22497206.
Adeyemi EO. Gender inequities in sexually transmitted infections: implications for HIV infection and control in Lagos State, Nigeria. Infectious disease reports. 2011 Mar 8; 3 (1): e7. PubMed PMID: 24470905. Pubmed Central PMCID: 3892601.
Scheidell JD, Beau De Rochars VM, Seraphin MN, Hobbs MM, Morris JG, Jr., Celestin JP, et al. Socioeconomic Vulnerability and Sexually Transmitted Infection Among Pregnant Haitian Women. Sexually transmitted diseases. 2018 Sep; 45 (9): 626-31. PubMed PMID: 29697553. Pubmed Central PMCID: 6086731.
Lochner HJ, 3rd, Maraqa NF. Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care. Paediatric drugs. 2018 Dec; 20 (6): 501-9. PubMed PMID: 30128814.
Mutagoma M, Balisanga H, Remera E, Gupta N, Malamba SS, Riedel DJ, et al. Ten-year trends of syphilis in sero-surveillance of pregnant women in Rwanda and correlates of syphilis-HIV co-infection. International journal of STD & AIDS. 2017 Jan; 28 (1): 45-53. PubMed PMID: 26692548. Pubmed Central PMCID: 4970953.
Tareke K, Munshea A, Nibret E. Seroprevalence of syphilis and its risk factors among pregnant women attending antenatal care at Felege Hiwot Referral Hospital, Bahir Dar, northwest Ethiopia: a cross-sectional study. BMC research notes. 2019 Jan 31; 12 (1): 69. PubMed PMID: 30704517. Pubmed Central PMCID: 6357495.
Dionne-Odom J, Mbah R, Rembert NJ, Tancho S, Halle-Ekane GE, Enah C, et al. Hepatitis B, HIV, and Syphilis Seroprevalence in Pregnant Women and Blood Donors in Cameroon. Infectious diseases in obstetrics and gynecology. 2016; 4359401. PubMed PMID: 27578957. Pubmed Central PMCID: 4992796.
Gasana M, Vandebriel G, Kabanda G, Tsiouris SJ, Justman J, Sahabo R, et al. Integrating tuberculosis and HIV care in rural Rwanda. The international journal of tuberculosis and lung disease: the official journal of the International Union against Tuberculosis and Lung Disease. 2008 Mar; 12 (3 Suppl 1): 39-43. PubMed PMID: 18302821. Pubmed Central PMCID: 5094056.
Niama RF, Loukabou Bongolo NC, Bayonne Kombo ES, Yengo R, Mayengue PI, Mandingha Kosso EB, et al. Syphilis and HIV infections among pregnant women attending antenatal clinics in Republic of Congo. The Pan African medical journal. 2017; 28: 8. PubMed PMID: 29138654. Pubmed Central PMCID: 5681004.
Biadgo B, Hassen A, Getaneh M, Tesfa H, Jaleta KN, Eshetu T, et al. Syphilis and human immunodeficiency virus infections among pregnant women attending antenatal care clinic of Gondar family guidance association, Northwest Ethiopia: implication for prevention of mother to child transmission. Reproductive health. 2019 Mar 4; 16 (1): 27. PubMed PMID: 30832694. Pubmed Central PMCID: 6399918.
Mutagoma M, Remera E, Sebuhoro D, Kanters S, Riedel DJ, Nsanzimana S. The Prevalence of Syphilis Infection and Its Associated Factors in the General Population of Rwanda: A National Household-Based Survey. Journal of sexually transmitted diseases. 2016; 4980417. PubMed PMID: 27123356. Pubmed Central PMCID: 4829711.
Kayirangwa E, Hanson J, Munyakazi L, Kabeja A. Current trends in Rwanda's HIV/AIDS epidemic. Sexually transmitted infections. 2006 Apr; 82 Suppl 1: i27-31. PubMed PMID: 16581756. Pubmed Central PMCID: 2593071.
Manyahi J, Jullu BS, Abuya MI, Juma J, Ndayongeje J, Kilama B, et al. Prevalence of HIV and syphilis infections among pregnant women attending antenatal clinics in Tanzania, 2011. BMC public health. 2015 May 22; 15: 501. PubMed PMID: 25994129. Pubmed Central PMCID: 4492104.
Assefa A. A three year retrospective study on seroprevalence of syphilis among pregnant women at Gondar University Teaching Hospital, Ethiopia. African health sciences. 2014 Mar; 14 (1): 119-24. PubMed PMID: 26060467. Pubmed Central PMCID: 4449084.
Thuong NV, Nhung VT, Nghia KV, Tram LT, O'Farrell N. HIV in female sex workers in five border provinces of Vietnam. Sexually transmitted infections. 2005 Dec; 81 (6): 477-9. PubMed PMID: 16326850. Pubmed Central PMCID: 1745073.
Li R, Liao MZ, Huang PX, Yang XG, Zhu XY, Su SL, et al. [Factors related to syphilis and other infections among female drug users in Shandong women's compulsory drug rehabilitation center in 2015]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2016 Sep 6; 50 (9): 820-4. PubMed PMID: 27655604.