Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol

Díaz Arizmendi Diana Elizabeth; Mendieta Zerón Hugo

doi:doi:10.11648/j.ajim.20200801.14

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Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol

Díaz Arizmendi Diana Elizabeth, Mendieta Zerón Hugo

Published in American Journal of Internal Medicine (Volume 8, Issue 1)

Received: 27 December 2019 Accepted: 6 January 2020 Published: 13 January 2020

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Abstract

Hyperthyroidism is one of the main endocrinopathies during pregnancy. The aim of this project was to identify the degree of control of hyperthyroid pregnant women based on the recommendations of the American Thyroid Association (ATA) in a real situation without the availability of propylthiouracil. This was a descriptive, retrospective and longitudinal study, including medical files of pregnant women with hyperthyroidism between 18 and 35 years. They were classified as having "Adequate" control if their thyroid profiles were within the recommendations of the ATA and had no adrenergic symptoms; and were categorized as having "Inadequate" control if they were not stabilized with monotherapy, or if they required high doses of antithyroid drugs or beta-blockers or showed serious complications including the need of an Intensive Care Unit (ICU) for mothers or neonates. The Chi square test was performed between treatment groups during the third trimester and the complications of pregnant women or neonates. A total of 173 hyperthyroid pregnant women were studied with an average age of 21 ± 4.7 years. Of the 33 patients with hyperthyroidism who received monotherapy with methimazole until the end of pregnancy, 23 (69.69%) were classified as having "Adequate" control. In a real life situation there is delay in the diagnosis of hyperthyroidism during pregnancy but even without propylthiuracil, an “Adequate” control can be reached in up to 20.53% of cases based on a methimazole monotherapy.

Published in	American Journal of Internal Medicine (Volume 8, Issue 1) This article belongs to the Special Issue Thyroid in Systemic Diseases
DOI	10.11648/j.ajim.20200801.14
Page(s)	19-23
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Degree of Control, Hyperthyroidism, Methimazole, Pregnancy, Propranolol

References

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APA Style

Díaz Arizmendi Diana Elizabeth, Mendieta Zerón Hugo. (2020). Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. American Journal of Internal Medicine, 8(1), 19-23. https://doi.org/10.11648/j.ajim.20200801.14

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ACS Style

Díaz Arizmendi Diana Elizabeth; Mendieta Zerón Hugo. Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. Am. J. Intern. Med. 2020, 8(1), 19-23. doi: 10.11648/j.ajim.20200801.14

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AMA Style

Díaz Arizmendi Diana Elizabeth, Mendieta Zerón Hugo. Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. Am J Intern Med. 2020;8(1):19-23. doi: 10.11648/j.ajim.20200801.14

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@article{10.11648/j.ajim.20200801.14,
  author = {Díaz Arizmendi Diana Elizabeth and Mendieta Zerón Hugo},
  title = {Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {1},
  pages = {19-23},
  doi = {10.11648/j.ajim.20200801.14},
  url = {https://doi.org/10.11648/j.ajim.20200801.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200801.14},
  abstract = {Hyperthyroidism is one of the main endocrinopathies during pregnancy. The aim of this project was to identify the degree of control of hyperthyroid pregnant women based on the recommendations of the American Thyroid Association (ATA) in a real situation without the availability of propylthiouracil. This was a descriptive, retrospective and longitudinal study, including medical files of pregnant women with hyperthyroidism between 18 and 35 years. They were classified as having "Adequate" control if their thyroid profiles were within the recommendations of the ATA and had no adrenergic symptoms; and were categorized as having "Inadequate" control if they were not stabilized with monotherapy, or if they required high doses of antithyroid drugs or beta-blockers or showed serious complications including the need of an Intensive Care Unit (ICU) for mothers or neonates. The Chi square test was performed between treatment groups during the third trimester and the complications of pregnant women or neonates. A total of 173 hyperthyroid pregnant women were studied with an average age of 21 ± 4.7 years. Of the 33 patients with hyperthyroidism who received monotherapy with methimazole until the end of pregnancy, 23 (69.69%) were classified as having "Adequate" control. In a real life situation there is delay in the diagnosis of hyperthyroidism during pregnancy but even without propylthiuracil, an “Adequate” control can be reached in up to 20.53% of cases based on a methimazole monotherapy.},
 year = {2020}
}

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TY  - JOUR
T1  - Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol
AU  - Díaz Arizmendi Diana Elizabeth
AU  - Mendieta Zerón Hugo
Y1  - 2020/01/13
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DO  - 10.11648/j.ajim.20200801.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
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EP  - 23
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200801.14
AB  - Hyperthyroidism is one of the main endocrinopathies during pregnancy. The aim of this project was to identify the degree of control of hyperthyroid pregnant women based on the recommendations of the American Thyroid Association (ATA) in a real situation without the availability of propylthiouracil. This was a descriptive, retrospective and longitudinal study, including medical files of pregnant women with hyperthyroidism between 18 and 35 years. They were classified as having "Adequate" control if their thyroid profiles were within the recommendations of the ATA and had no adrenergic symptoms; and were categorized as having "Inadequate" control if they were not stabilized with monotherapy, or if they required high doses of antithyroid drugs or beta-blockers or showed serious complications including the need of an Intensive Care Unit (ICU) for mothers or neonates. The Chi square test was performed between treatment groups during the third trimester and the complications of pregnant women or neonates. A total of 173 hyperthyroid pregnant women were studied with an average age of 21 ± 4.7 years. Of the 33 patients with hyperthyroidism who received monotherapy with methimazole until the end of pregnancy, 23 (69.69%) were classified as having "Adequate" control. In a real life situation there is delay in the diagnosis of hyperthyroidism during pregnancy but even without propylthiuracil, an “Adequate” control can be reached in up to 20.53% of cases based on a methimazole monotherapy.
VL  - 8
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Author Information

Díaz Arizmendi Diana Elizabeth

Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico
Mendieta Zerón Hugo

Faculty of Medicine, Autonomous University of the State of Mexico, Toluca, Mexico;Research Department, “Mónica Pretelini Sáenz” Maternal-Perinatal Hospital (HMPMPS) and Ciprés Grupo Médico (CGM), Toluca, Mexico

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APA Style

Díaz Arizmendi Diana Elizabeth, Mendieta Zerón Hugo. (2020). Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. American Journal of Internal Medicine, 8(1), 19-23. https://doi.org/10.11648/j.ajim.20200801.14

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ACS Style

Díaz Arizmendi Diana Elizabeth; Mendieta Zerón Hugo. Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. Am. J. Intern. Med. 2020, 8(1), 19-23. doi: 10.11648/j.ajim.20200801.14

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AMA Style

Díaz Arizmendi Diana Elizabeth, Mendieta Zerón Hugo. Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol. Am J Intern Med. 2020;8(1):19-23. doi: 10.11648/j.ajim.20200801.14

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@article{10.11648/j.ajim.20200801.14,
  author = {Díaz Arizmendi Diana Elizabeth and Mendieta Zerón Hugo},
  title = {Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {1},
  pages = {19-23},
  doi = {10.11648/j.ajim.20200801.14},
  url = {https://doi.org/10.11648/j.ajim.20200801.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200801.14},
  abstract = {Hyperthyroidism is one of the main endocrinopathies during pregnancy. The aim of this project was to identify the degree of control of hyperthyroid pregnant women based on the recommendations of the American Thyroid Association (ATA) in a real situation without the availability of propylthiouracil. This was a descriptive, retrospective and longitudinal study, including medical files of pregnant women with hyperthyroidism between 18 and 35 years. They were classified as having "Adequate" control if their thyroid profiles were within the recommendations of the ATA and had no adrenergic symptoms; and were categorized as having "Inadequate" control if they were not stabilized with monotherapy, or if they required high doses of antithyroid drugs or beta-blockers or showed serious complications including the need of an Intensive Care Unit (ICU) for mothers or neonates. The Chi square test was performed between treatment groups during the third trimester and the complications of pregnant women or neonates. A total of 173 hyperthyroid pregnant women were studied with an average age of 21 ± 4.7 years. Of the 33 patients with hyperthyroidism who received monotherapy with methimazole until the end of pregnancy, 23 (69.69%) were classified as having "Adequate" control. In a real life situation there is delay in the diagnosis of hyperthyroidism during pregnancy but even without propylthiuracil, an “Adequate” control can be reached in up to 20.53% of cases based on a methimazole monotherapy.},
 year = {2020}
}

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TY  - JOUR
T1  - Degree of Control and Main Complications of Hyperthyroid Pregnant Women in a Real Life Experience with Methimazol
AU  - Díaz Arizmendi Diana Elizabeth
AU  - Mendieta Zerón Hugo
Y1  - 2020/01/13
PY  - 2020
N1  - https://doi.org/10.11648/j.ajim.20200801.14
DO  - 10.11648/j.ajim.20200801.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 19
EP  - 23
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200801.14
AB  - Hyperthyroidism is one of the main endocrinopathies during pregnancy. The aim of this project was to identify the degree of control of hyperthyroid pregnant women based on the recommendations of the American Thyroid Association (ATA) in a real situation without the availability of propylthiouracil. This was a descriptive, retrospective and longitudinal study, including medical files of pregnant women with hyperthyroidism between 18 and 35 years. They were classified as having "Adequate" control if their thyroid profiles were within the recommendations of the ATA and had no adrenergic symptoms; and were categorized as having "Inadequate" control if they were not stabilized with monotherapy, or if they required high doses of antithyroid drugs or beta-blockers or showed serious complications including the need of an Intensive Care Unit (ICU) for mothers or neonates. The Chi square test was performed between treatment groups during the third trimester and the complications of pregnant women or neonates. A total of 173 hyperthyroid pregnant women were studied with an average age of 21 ± 4.7 years. Of the 33 patients with hyperthyroidism who received monotherapy with methimazole until the end of pregnancy, 23 (69.69%) were classified as having "Adequate" control. In a real life situation there is delay in the diagnosis of hyperthyroidism during pregnancy but even without propylthiuracil, an “Adequate” control can be reached in up to 20.53% of cases based on a methimazole monotherapy.
VL  - 8
IS  - 1
ER  -

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