1500 morphine-absorbed hair was collected, and the hair was ground with a quick grinder to extract the morphine component of the hair. The morphine was qualitatively detected by gas chromatography/mass spectrometry (GC/MS). The test results were processed by statistical software and the hair was evaluated. Morphine positive tests results. A total of 1500 morphine users were found to have 1465 morphine-positive (97.7%) in the hair-dried group and 998 morphine-positive (66.5%) in the unpolished hair group. The results were statistically significant (P < 0.005). In the analysis of the influencing factors of the testing method, the sample collected by the sex, age, and hair collection location of the drug addicts had no effect on the test results (P>0.05); the chemical dyeing, regardless of whether the hair was ground or not, showed a significant decrease in morphine positive detection. The test results have an effect (P<0.05). The results of the study showed that morphine was extracted from ground hair and the positive detection of morphine was significantly improved, with a positive rate of 97.67%. This prevented the missed detection in the drug addiction certification work and made the certification test more scientific and accurate.
| Published in | Journal of Drug Design and Medicinal Chemistry (Volume 4, Issue 1) |
| DOI | 10.11648/j.jddmc.20180401.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Hair Grinding, Extraction Rate, Morphine, Addiction Identification
| [1] | "Approved Measures for Drug Addiction" Ministry of Public Security of the People's Republic of China and Order No. 115 of the Ministry of Health of the People's Republic of China April 1, 2011. |
| [2] | Tang. Y. Drug dependence and prevention of recurrence. Drug dependence on China, 1997, 6 (2): 73-76. |
| [3] | Men GP in Jia, Zhang Q i, X u ying. hair drug analysis. Beijing, Chinese peoples public security university press, 2001: 165-178. |
| [4] | A. Orfanidis; O. Mastrogianni; A. Koukou; G. Psarros; H. Gika; G. Theodoridis; N. Raikos. A GC–MS method for the detection and quantitation of ten major drugs of abuse in human hair samples. Journal of Chromatography B 2016- Elsevierjournal 10. 1016/j. jchromb. 2016. 11. 011. |
| [5] | Sun Ying-Ying; Xiang Ping; Shen Min. Simultaneous determination of 11 opiates in hair by liquid chromatography-tandem mass spectrometry [J]. Yaoxue Xuebao 2012-12 PubMed. |
| [6] | Grabenauer Megan; Bynum Nichole D; Moore Katherine N; White Robert M; Mitchell John M; Hayes Eugene D; Flegel Ronald. Detection and quantification of codeine-6-glucuronide, hydromorphone-3-glucuronide, oxymorphone-3-glucuronide, morphine 3-glucuronide and morphine-6-glucuronide in human hair from opioid users by LC-MS-MS. Grabenauer Megan Journal of analytical toxicology 2017- PubMed 10. 1093/jat/bkx086 |
| [7] | Concheiro M, Simoes SM, Quintela O, de Castro A, Dias MJ, Cruz A, Lopez-Rivadulla M. Fast LC-MS/MS method for the determination of amphetamine, methamphetamine, MDA, MDMA, MDEA, MBDB and PMA in urine. Forensic science international. 2007, 171:44-51. |
| [8] | He Y, J. KY. J Chromatogr A. 2006, 1133:50-55. |
| [9] | Musshoff F, Arrey T, Strupat K. Determination of cocaine, cocaine metabolites and cannabinoids in single hairs by MALDI Fourier transform mass spectrometry--preliminary results. Drug testing and analysis 2013, 5 (5): 361-365. |
| [10] | Maria N, Claudia T, Lucia B. Cross-reactivities of 41new amphetamine designer drugs to EMIT immunoassays. Forensic Toxicology, 2012, 31 (1): 133-137. |
| [11] | Cheong JC, Suh S, Ko BJ, Lee JI, Kim JY, Suh YJ, In MK. Screening method for the detection of methamphetamine in hair using fluorescence polarization immunoassay. Journal of analytical toxicology, 2013, 37 (4): 217-221. |
| [12] | Shao. M. Try to talk about the cause of drug abuse. The rule of law and society, 2005, 3:250-251. |
| [13] | Li. X, Yuan. C, Wen. H. The drug addicts and personal integrity. Chinese journal of drug dependence, 2005, 14 (3): 226-228. |
| [14] | S. Nikfar; M. Jaberidoost. Hair. 2014 Elsevier 10. 1016/B978-0-12-386454-3. 00610-2. |
| [15] | Nishida M. Yashiki M. Namera A. et al. J Chromatogr B. 2006, 842:106-110. |
| [16] | Gentili S. Cornetta M. Macchia T. J Chromatogr B. 2004, 801:289-296. |
| [17] | Polettini A. Stramesi C. Vignali C. et al. Foren Sci Int. 1997, 84:259-269. |
| [18] | Cordero R. Paterson S. Chromatogr B. 2007, 850:423-431. |
| [19] | Cappelle Delphine; De Keukeleire Steven; Neels Hugo; Been Frederic; De Doncker Mireille; Dom Geert; Crunelle Cleo L; Covaci Adrian; van Nuijs Alexander L N. Keratinous matrices for the assessment of drugs of abuse consumption: A correlation study between hair and nails. Drug testing and analysis [J]. 2018- PubMed 10. 1002/dta. 2356. |
| [20] | Cao Xiaoci, DING Penglin, ZHONG Mingtian et al. Correlation between TCM syndromes and liver function indexes in different product addicts [J]. Chinese Journal of Drug Dependence, 2016, 25(2): 182-185. |
| [21] | Xie P, Wang TJ, Yin G. Hair testing drug abuse technology. Drug dependence on China, 2014, 20 (1): 120-126 |
| [22] | Klima Miriam; Altenburger Markus J; Kempf Jürgen; Auwärter Volker; Neukamm Merja A. Determination of medicinal and illicit drugs in post mortem dental hard tissues and comparison with analytical results for body fluids and hair samples. Forensic science international. 2016- PubMed 10. 1016/j. forsciint. 2016. 02. 021. |
| [23] | Meng. P, He. H, Zhu. D. Analysis and explanation of drugs and their metabolites in drug abusers’ hair. Journal of pharmaceutical analysis, 2008, 5:709-714. |
APA Style
Xiao Ruisen, Huang Ping, Wang Hong, Li Jinwei. (2018). Study on the Extraction Rate of Morphine Before and After Hair Grinding. Journal of Drug Design and Medicinal Chemistry, 4(1), 1-4. https://doi.org/10.11648/j.jddmc.20180401.11
ACS Style
Xiao Ruisen; Huang Ping; Wang Hong; Li Jinwei. Study on the Extraction Rate of Morphine Before and After Hair Grinding. J. Drug Des. Med. Chem. 2018, 4(1), 1-4. doi: 10.11648/j.jddmc.20180401.11
AMA Style
Xiao Ruisen, Huang Ping, Wang Hong, Li Jinwei. Study on the Extraction Rate of Morphine Before and After Hair Grinding. J Drug Des Med Chem. 2018;4(1):1-4. doi: 10.11648/j.jddmc.20180401.11
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.jddmc.20180401.11,
author = {Xiao Ruisen and Huang Ping and Wang Hong and Li Jinwei},
title = {Study on the Extraction Rate of Morphine Before and After Hair Grinding},
journal = {Journal of Drug Design and Medicinal Chemistry},
volume = {4},
number = {1},
pages = {1-4},
doi = {10.11648/j.jddmc.20180401.11},
url = {https://doi.org/10.11648/j.jddmc.20180401.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jddmc.20180401.11},
abstract = {1500 morphine-absorbed hair was collected, and the hair was ground with a quick grinder to extract the morphine component of the hair. The morphine was qualitatively detected by gas chromatography/mass spectrometry (GC/MS). The test results were processed by statistical software and the hair was evaluated. Morphine positive tests results. A total of 1500 morphine users were found to have 1465 morphine-positive (97.7%) in the hair-dried group and 998 morphine-positive (66.5%) in the unpolished hair group. The results were statistically significant (P 0.05); the chemical dyeing, regardless of whether the hair was ground or not, showed a significant decrease in morphine positive detection. The test results have an effect (P<0.05). The results of the study showed that morphine was extracted from ground hair and the positive detection of morphine was significantly improved, with a positive rate of 97.67%. This prevented the missed detection in the drug addiction certification work and made the certification test more scientific and accurate.},
year = {2018}
}
TY - JOUR T1 - Study on the Extraction Rate of Morphine Before and After Hair Grinding AU - Xiao Ruisen AU - Huang Ping AU - Wang Hong AU - Li Jinwei Y1 - 2018/06/19 PY - 2018 N1 - https://doi.org/10.11648/j.jddmc.20180401.11 DO - 10.11648/j.jddmc.20180401.11 T2 - Journal of Drug Design and Medicinal Chemistry JF - Journal of Drug Design and Medicinal Chemistry JO - Journal of Drug Design and Medicinal Chemistry SP - 1 EP - 4 PB - Science Publishing Group SN - 2472-3576 UR - https://doi.org/10.11648/j.jddmc.20180401.11 AB - 1500 morphine-absorbed hair was collected, and the hair was ground with a quick grinder to extract the morphine component of the hair. The morphine was qualitatively detected by gas chromatography/mass spectrometry (GC/MS). The test results were processed by statistical software and the hair was evaluated. Morphine positive tests results. A total of 1500 morphine users were found to have 1465 morphine-positive (97.7%) in the hair-dried group and 998 morphine-positive (66.5%) in the unpolished hair group. The results were statistically significant (P 0.05); the chemical dyeing, regardless of whether the hair was ground or not, showed a significant decrease in morphine positive detection. The test results have an effect (P<0.05). The results of the study showed that morphine was extracted from ground hair and the positive detection of morphine was significantly improved, with a positive rate of 97.67%. This prevented the missed detection in the drug addiction certification work and made the certification test more scientific and accurate. VL - 4 IS - 1 ER -
Information
Email: