American Journal of Pediatrics

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A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I

Received: Sep. 14, 2016    Accepted: Oct. 12, 2016    Published: Mar. 17, 2017
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Abstract

Ischemic stroke is an infrequent disease of pediatric patients. We report a case of 2 year old child with neurofibromatosis, who had acute hemiplegia and severe hypertension (required artery angioplasty) due to both cerebral vascular disease and renal artery stenosis.

DOI 10.11648/j.ajp.20170301.11
Published in American Journal of Pediatrics ( Volume 3, Issue 1, January 2017 )
Page(s) 1-3
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Neurofibromatosis, Vasculopathy, Stroke, Renovascular Stenosis

References
[1] Lammert M, Friedman JM, Kluwe L, Mautner VF. Prevalence of neurofibromatosis 1 in German children at elementary school enrollment. Arch Dermatol 2005; 141: 71.
[2] Friedman JM. Neurofibromatosis 1. GeneReviews® [Internet]. http://www.ncbi.nlm.nih.gov/books/NBK1109/.
[3] Rea D, Brandsema JF, Armstrong D, et al. Cerebral arteriopathy in children with neurofibromatosis type 1. Pediatrics 2009; 124: e476.
[4] Cairns AG, North KN. Cerebrovascular dysplasia in neurofibromatosis type 1. J Neurol Neurosurg Psychiatry 2008; 79: 1165.
[5] McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, et al. Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr 2007; 150: 640-644.
[6] Hiner LB, Falkner B. Renovascular hypertension in children. Pediatr Clin North Am. 1993; 40: 123-140.
[7] Stanley JC, Criado E, Upchurch Jr GR, Brophy PD, Cho KJ, Rectenwald JE. Pediatric renovascular hypertension: 132 primary and 30 secondary operations in 97 children. J Vasc Surg. 2006; 44: 1219-1229.
[8] Boulanger JM1, Larbrisseau A. Neurofibromatosis type 1 in a pediatric population: Ste-Justine's experience. Can J Neurol Sci. 2005; 32 (2): 225-231.
[9] Tekin M, Bodurtha JN, Riccardi VM. Cafe au lait spots: the pediatrician's perspective. Pediatr Rev. 2001; 22 (3): 82-90.
[10] Albahri Z, Lukeš A And Rozsíval P. Peripheral facial paralysis in an infant with malignant hypertension and suspected neurofibromatosis disease. Journal of the Neurological Science. 2015; (357): 1: 172–e173.
[11] Malav IC, Kothari SS. Renal artery stenosis due to neurofibromatosis. Ann Pediatr Cardioly. 2009; 2: 167-169.
[12] A. E. Lin, P. Birch, B. R. Korf, R. Tenconi, M. Niimura, M. Poyhonen, et al. Cardiovascular malformations and other cardiovascular abnormalities in Neurofibromatosis type I. Am J Med Genet. 2000; 95: 108-117.
[13] Friedman J. M., J. Arbiser, J. A. Epstein, D. H. Gutman, Sj Huot, A. E. Lin, et al. Cardiovascular disease in neurofibromatosis 1: report of the NF1 cardiovascular task force Genet Med 2002; 4: 105-111.
[14] Konig K, Gellermann J, Querfeld U, Schneider MB. Treatment of severe renal artery stenosis by percutaneous transluminal renal angioplasty and stent implantation: review of the pediatric experience: apropos of two cases. Pediatr Nephrol. 2006; 21: 663-671.
[15] Meyers KE1, Cahill AM, Sethna C. Interventions for pediatric renovascular hypertension. Curr Hypertens Rep. 2014; 16 (4): 422.
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  • APA Style

    Kusa K., Rozsival P., Melek J., Lukeš A., Štefáčková Š., et al. (2017). A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I. American Journal of Pediatrics, 3(1), 1-3. https://doi.org/10.11648/j.ajp.20170301.11

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    ACS Style

    Kusa K.; Rozsival P.; Melek J.; Lukeš A.; Štefáčková Š., et al. A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I. Am. J. Pediatr. 2017, 3(1), 1-3. doi: 10.11648/j.ajp.20170301.11

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    AMA Style

    Kusa K., Rozsival P., Melek J., Lukeš A., Štefáčková Š., et al. A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I. Am J Pediatr. 2017;3(1):1-3. doi: 10.11648/j.ajp.20170301.11

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  • @article{10.11648/j.ajp.20170301.11,
      author = {Kusa K. and Rozsival P. and Melek J. and Lukeš A. and Štefáčková Š. and Albahri Z.},
      title = {A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I},
      journal = {American Journal of Pediatrics},
      volume = {3},
      number = {1},
      pages = {1-3},
      doi = {10.11648/j.ajp.20170301.11},
      url = {https://doi.org/10.11648/j.ajp.20170301.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajp.20170301.11},
      abstract = {Ischemic stroke is an infrequent disease of pediatric patients. We report a case of 2 year old child with neurofibromatosis, who had acute hemiplegia and severe hypertension (required artery angioplasty) due to both cerebral vascular disease and renal artery stenosis.},
     year = {2017}
    }
    

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Author Information
  • Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic

  • Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic

  • Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic

  • Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic

  • Section