Journal of Cancer Treatment and Research

| Peer-Reviewed |

Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area

Received: Dec. 17, 2019    Accepted: Jan. 03, 2020    Published: Jan. 13, 2020
Views:       Downloads:

Share This Article

Abstract

Background: At present, the spatial studies of liver cancer are too large for observation, or lack systematic spatial epidemics and statistical analyses, so it is difficult to put forward more targeted regional prevention and control measures. This study takes the natural village of Longkou City, Shandong as a small regional research unit, to systematically analyze the spatial structure and spatial heterogeneity of liver cancer in the small region (village as a unit), and provide a scientific basis for the development of regional prevention and control measures for more targeted liver cancer and its related diseases. Methods: Based on the database of the integrated management information system for chronic diseases and death monitoring in Shandong Center for Disease Control and Prevention, the spatial epidemiology and spatial statistics methods were combined in the framework of geographic information system (GIS). Results: The results of spatial distribution showed that there was obvious spatial heterogeneity on liver cancer in Longkou City, and there were many high incidence and high death areas scattered in the distribution. The spatial scanning and space-time scanning results of liver cancer showed that there were relatively fixed high incidence and high death villages in the small area of Longkou City. Conclusion: This study suggests that the liver cancer in Longkou City has a local geographic risk factor, which may have obvious high incidence area, and time factors have a certain influence on the space area of liver cancer. It is necessary to further carry out the geographical weight regression and risk factors analysis, and expand the study model.

DOI 10.11648/j.jctr.20200801.12
Published in Journal of Cancer Treatment and Research ( Volume 8, Issue 1, March 2020 )
Page(s) 10-17
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Small Geographical Area, Liver Cancer, Spatial Epidemiology

References
[1] Doll R (1967). Prevention of Cancer: Pointers from Epidemiology [M]. London: Nuffeld Provincial Hospitals Trust.
[2] Bing Li, Junyao Li. Death and distribution characteristics of malignant tumors in China [J]. Chinese Journal of oncology, 1980, 2 (1): 1.
[3] SinoMaps Press. The Editoarial Committee for the Atlas of Cancer Mortality in the People's Republic of China. Atlas of cancer mortality in the People's Republic of China [M]. Beijing, China, 1979: 40-46.
[4] Wanqing Chen, Xiaonong Zou, Siwei Zhang. Geographical distribution of mortality of liver cancer in China [J]. Journal of Practical Oncology, 2008, 22 (9): 201-203.
[5] Min Weng, Wanyi Li, Shiliang Su, Zhongliang Cai. Study on the spatial pattern of the incidence of liver cancer from the perspective of social deprivation -- Taking Shenzhen as an example of [J]. Modern preventive medicine, 2016, 43 (8): 1355-1358.
[6] Zhang W, Wang L, Fang L, et al. Spatial analysis of malaria in Anhui province, China [J]. Malar J, 2008, 7: 206.
[7] Ruihong Liu. Spatial epidemiological characteristics and risk factors of stroke in small areas [D]. Jinan: Shandong University, 2016.
[8] MKF. A spatial scan statistic [J]. Communications in Statistics: Theory and Methods, 1997, 26: 1481-1496.
[9] Luc A. Local indicators of spatial association-LISA [Z]. 1995: 27, 93-115.
[10] Areias C, Briz T, Nunes C. Pulmonary tuberculosis space-time clustering and spatial variation in temporal trends in Portugal, 2000-2010: an updated analysis [J]. Epidemiol Infect, 2015, 143 (15): 3211-3219.
[11] Bellec S, Hemon D, Rudant J, et al. Spatial and space-time clustering of childhood acute leukaemia in France from 1990 to 2000: a nationwide study [J]. Br J Cancer, 2006, 94 (5): 763-770.
[12] Yiannakoulias N. Using population attributable risk to understand geographic disease clusters [J]. Health Place, 2009, 15 (4): 1142-1148.
[13] Wild CP (2012). The role of cancer research in noncommunicable disease control [J]. Natl Cancer Inst, 104: 1051–1058. http://dx.doi.org/10.1093/jnci/djs262.
[14] Aiqiang Xu, Fuzhong Xue, Xiaolei Guo, Jiandong Sun. Status of malignant tumor death and its spatial epidemiology in Shandong Province [M]. Jinan: Shandong Science and Technology Press, 2015 (1): 50.
[15] McGlynn KA, et al (2005). Epidemiology and natural history of hepatocellular carcinoma [J]. Best Practice & Research in Clinical Gastroenterology, 19 (1): 3-23.
[16] E1-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma [J]. Gastroenterology, 2012, 142 (6): 1264-1273. DOI: 10.1053/j.gastro.2011.12.061.
Cite This Article
  • APA Style

    Jing Qu, Haiyun Liu, Jian Xue, Jianjun Xu, Maobo Wang, et al. (2020). Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area. Journal of Cancer Treatment and Research, 8(1), 10-17. https://doi.org/10.11648/j.jctr.20200801.12

    Copy | Download

    ACS Style

    Jing Qu; Haiyun Liu; Jian Xue; Jianjun Xu; Maobo Wang, et al. Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area. J. Cancer Treat. Res. 2020, 8(1), 10-17. doi: 10.11648/j.jctr.20200801.12

    Copy | Download

    AMA Style

    Jing Qu, Haiyun Liu, Jian Xue, Jianjun Xu, Maobo Wang, et al. Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area. J Cancer Treat Res. 2020;8(1):10-17. doi: 10.11648/j.jctr.20200801.12

    Copy | Download

  • @article{10.11648/j.jctr.20200801.12,
      author = {Jing Qu and Haiyun Liu and Jian Xue and Jianjun Xu and Maobo Wang and Fuzhong Xue},
      title = {Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area},
      journal = {Journal of Cancer Treatment and Research},
      volume = {8},
      number = {1},
      pages = {10-17},
      doi = {10.11648/j.jctr.20200801.12},
      url = {https://doi.org/10.11648/j.jctr.20200801.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.jctr.20200801.12},
      abstract = {Background: At present, the spatial studies of liver cancer are too large for observation, or lack systematic spatial epidemics and statistical analyses, so it is difficult to put forward more targeted regional prevention and control measures. This study takes the natural village of Longkou City, Shandong as a small regional research unit, to systematically analyze the spatial structure and spatial heterogeneity of liver cancer in the small region (village as a unit), and provide a scientific basis for the development of regional prevention and control measures for more targeted liver cancer and its related diseases. Methods: Based on the database of the integrated management information system for chronic diseases and death monitoring in Shandong Center for Disease Control and Prevention, the spatial epidemiology and spatial statistics methods were combined in the framework of geographic information system (GIS). Results: The results of spatial distribution showed that there was obvious spatial heterogeneity on liver cancer in Longkou City, and there were many high incidence and high death areas scattered in the distribution. The spatial scanning and space-time scanning results of liver cancer showed that there were relatively fixed high incidence and high death villages in the small area of Longkou City. Conclusion: This study suggests that the liver cancer in Longkou City has a local geographic risk factor, which may have obvious high incidence area, and time factors have a certain influence on the space area of liver cancer. It is necessary to further carry out the geographical weight regression and risk factors analysis, and expand the study model.},
     year = {2020}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Analysis of Spatial Epidemic Characteristics of Liver Cancer in Small Geographical Area
    AU  - Jing Qu
    AU  - Haiyun Liu
    AU  - Jian Xue
    AU  - Jianjun Xu
    AU  - Maobo Wang
    AU  - Fuzhong Xue
    Y1  - 2020/01/13
    PY  - 2020
    N1  - https://doi.org/10.11648/j.jctr.20200801.12
    DO  - 10.11648/j.jctr.20200801.12
    T2  - Journal of Cancer Treatment and Research
    JF  - Journal of Cancer Treatment and Research
    JO  - Journal of Cancer Treatment and Research
    SP  - 10
    EP  - 17
    PB  - Science Publishing Group
    SN  - 2376-7790
    UR  - https://doi.org/10.11648/j.jctr.20200801.12
    AB  - Background: At present, the spatial studies of liver cancer are too large for observation, or lack systematic spatial epidemics and statistical analyses, so it is difficult to put forward more targeted regional prevention and control measures. This study takes the natural village of Longkou City, Shandong as a small regional research unit, to systematically analyze the spatial structure and spatial heterogeneity of liver cancer in the small region (village as a unit), and provide a scientific basis for the development of regional prevention and control measures for more targeted liver cancer and its related diseases. Methods: Based on the database of the integrated management information system for chronic diseases and death monitoring in Shandong Center for Disease Control and Prevention, the spatial epidemiology and spatial statistics methods were combined in the framework of geographic information system (GIS). Results: The results of spatial distribution showed that there was obvious spatial heterogeneity on liver cancer in Longkou City, and there were many high incidence and high death areas scattered in the distribution. The spatial scanning and space-time scanning results of liver cancer showed that there were relatively fixed high incidence and high death villages in the small area of Longkou City. Conclusion: This study suggests that the liver cancer in Longkou City has a local geographic risk factor, which may have obvious high incidence area, and time factors have a certain influence on the space area of liver cancer. It is necessary to further carry out the geographical weight regression and risk factors analysis, and expand the study model.
    VL  - 8
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Yantai Longkou County Center for Disease Control and Prevention, Yantai, China;Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan, China

  • Yantai Center for Disease Control and Prevention, Yantai, China

  • Yantai Center for Disease Control and Prevention, Yantai, China

  • Yantai Center for Disease Control and Prevention, Yantai, China

  • Yantai Center for Disease Control and Prevention, Yantai, China

  • Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan, China

  • Section