Introduction: The need for scientific literature relating post-COVID19 oral manifestations with depressive symptoms and the need to structure the variety of these and identify risk factors to prevent serious mental health affectations. Objective: To determine the relationship between oral manifestations and levels of depression in patients with post-COVID-19 sequels. Methods: A descriptive longitudinal study was carried out on 32 patients with mild COVID19 diseases, who persisted in their oral manifestations three months after diagnosis in the health area of the Marta Abreu Polyclinic, applying the Zung and Conde test to know their levels of depression. The statistical package SPSSv 21.0 and the chi-square test were used to process the data Results: In the research 81.2% of the patients present some level of depression, intervening the sociodemographic variable and if there is a significant relationship between the post-covid19 oral manifestations such as taste alteration and xerostomia with the appearance of emotional states such as depression. Conclusion: Post-COVID19 oral sequel can affect the emotional states influencing the level of depression of those who suffer from it.
Published in | American Journal of Nursing and Health Sciences (Volume 6, Issue 4) |
DOI | 10.11648/j.ajnhs.20250604.11 |
Page(s) | 89-95 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Depression, Oral Manifestations, Post-COVID19
Sociodemographic Variables | n=32 | Oral Sequels | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Alt. taste | Xerostomia | Oral Injuries | S. Burning Mouth | ||||||||
No | % | No | % | No | % | No | % | No | % | ||
Sex | masculine | 17 | 53,1 | 10 | 58,9 | 5 | 29,4 | 2 | 11,8 | 0 | 0,0 |
femenine | 15 | 46,9 | 4 | 26,7 | 5 | 33,3 | 3 | 20,0 | 3 | 20,0 | |
Age | 20-29 | 5 | 15,6 | 2 | 40,0 | 3 | 60,0 | 0 | 0,0 | 0 | 0,0 |
30-39 | 8 | 25,0 | 4 | 50,0 | 3 | 37,5 | 1 | 12,5 | 0 | 0,0 | |
40-49 | 7 | 21,9 | 2 | 28,6 | 2 | 28,6 | 2 | 28,6 | 1 | 14,3 | |
50-59 | 5 | 15,6 | 3 | 60,0 | 0 | 0,0 | 1 | 20,0 | 1 | 20,0 | |
60-69 | 4 | 12,5 | 1 | 25,0 | 2 | 50,0 | 0 | 0,0 | 1 | 25,0 | |
70-79 | 2 | 6,3 | 1 | 50,0 | 0 | 0,0 | 1 | 50,0 | 0 | 0,0 | |
< 80 | 1 | 3,1 | 1 | 100,0 | 0 | 0,0 | 0 | 0,0 | 0 | 0,0 | |
Marital status | accompanied | 16 | 50,0 | 8 | 50,0 | 6 | 37,5 | 2 | 12,5 | 0 | 0,0 |
unaccompanied | 16 | 50,0 | 6 | 37,5 | 4 | 25,0 | 3 | 18,7 | 3 | 18,7 | |
Employment status | employed | 13 | 40,6 | 8 | 61,5 | 3 | 23,1 | 2 | 15,3 | 0 | 0,0 |
not employed | 19 | 59,4 | 6 | 31,5 | 7 | 36,8 | 3 | 15,7 | 3 | 15,7 | |
Depends on your income | yes | 14 | 43,8 | 7 | 50,0 | 2 | 14,3 | 4 | 28,6 | 1 | 7,1 |
no | 18 | 56,3 | 7 | 38,8 | 8 | 44,4 | 1 | 15,6 | 2 | 11,1 |
Sociodemographic Variables n= 32 | Levels of depression | ||||||||
---|---|---|---|---|---|---|---|---|---|
Normal | Mild | Moderate | Severe | ||||||
No | % | No | % | No | % | No | % | ||
Age | 20-29 | 1 | 3,1 | 4 | 12,5 | 0 | 0,0 | 0 | 0,0 |
30-39 | 1 | 3,1 | 4 | 12,5 | 2 | 6,2 | 1 | 3,1 | |
40-49 | 2 | 6,2 | 2 | 6,2 | 2 | 6,2 | 1 | 3,1 | |
50-59 | 1 | 3,1 | 2 | 6,2 | 2 | 6,2 | 0 | 0,0 | |
60-69 | 1 | 3,1 | 0 | 0,0 | 1 | 3,1 | 2 | 6,2 | |
70-79 | 0 | 0,0 | 0 | 0,0 | 1 | 3,1 | 1 | 3,1 | |
< 80 | 0 | 0,0 | 0 | 0,0 | 0 | 0,0 | 1 | 3,1 | |
Subtotal | 6 | 18,7 | 12 | 37,5 | 8 | 25,0 | 6 | 18,7 | |
Marital status | accompanied | 2 | 6,2 | 2 | 6,2 | 4 | 12,5 | 3 | 9,4 |
unaccompanied | 4 | 12,5 | 5 | 15,6 | 4 | 12,5 | 3 | 9,4 | |
Subtotal | 6 | 18,7 | 7 | 21,8 | 8 | 25,0 | 6 | 18,7 | |
Employment status | employed | 3 | 9,4 | 6 | 18,7 | 3 | 9,4 | 1 | 3,1 |
not employed | 3 | 9,4 | 6 | 18,7 | 5 | 15,6 | 5 | 15,6 | |
Subtotal | 6 | 18,7 | 12 | 37,5 | 8 | 25,0 | 6 | 18,7 | |
Depends on your income | yes | 4 | 12,5 | 7 | 21,8 | 2 | 6,2 | 1 | 3,1 |
no | 2 | 6,2 | 5 | 15,6 | 6 | 18,7 | 5 | 15,6 | |
Subtotal | 6 | 18,7 | 12 | 37,5 | 8 | 25,0 | 6 | 18,7 |
Oral sequels | Total injuries | Levels of depression | p* | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Normal | Mild | Moderate | Severe | ||||||||
No | % | No | % | No | % | No | % | No | % | ||
Alt. Taste | 14 | 43,8 | 4 | 12,5 | 6 | 18,7 | 3 | 9,4 | 1 | 3,1 | 0,025 |
Xerostomia | 10 | 31,3 | 2 | 6,2 | 6 | 18,7 | 2 | 6,2 | 0 | 0,0 | 0,031 |
Oral Injuries | 5 | 15,6 | 0 | 0,0 | 0 | 0,0 | 3 | 9,4 | 2 | 6,2 | 0,652 |
S. Burning Mouth | 3 | 9,3 | 0 | 0,0 | 0 | 0,0 | 0 | 0,0 | 3 | 9,4 | 0,700 |
MINSAP | Ministry of Public Health |
PHC | Primary Health Care |
WHO | World Health Organization |
[1] | World Health Organization. Aclinical case definition of pos covid-19 condition by a Delphi consensus, 6 October 2021 [Internet]. Geneva. WHO; 2021 [citado 19 de agosto 2022]. Disponible en: |
[2] | Ministry of Public Health Protocol for the convalescent patient of covid-19 from Primary Health Care in Havana : MINSAP: 2020. |
[3] | Szczeniak D, Gladka A, Misiak B, Cyran A, Rymaszewska The SARS-CoV-2 and mental health. Frombiological mechanisms to social consequences. Prog Neuropsychopharmacol Biol Psychiatry, 2021 Jan 10; 104: 110046. |
[4] | American Psychiatric Association. Suplemento de manual diagnóstico y estadístico de trastornos mentales: 5th ed. Whashintong. DC. Asociacion de Psiquiatria 2018. |
[5] | Santomauro DF, Herrera AMM, Shadid J, Zheng P, Ashbaung C, Pigott DM, et al. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 dueto the covid-19 pandemic. The Lancet. 2021; 398 (10312): 1700-12. |
[6] | Taquet M, Luciano S, Gedes JR, Harrison PJ. Bidirectonial associations between covid-19 and psychiatric. Disorder: retrospective cohort studies of 62354 covid-19 cases in the USA. Lancet Psychiatry 2021: 8: 130-140. |
[7] | Amdal CD. Heath-related Quality of Life’s Issues, Including Symptoms, in Patients with Active covid-19 or Post covid-19, a Systematic Literature Review Quality of Life Research.2021: 1-15. |
[8] | Carrasco-Rueda CA, Vinitzky Brener I, Roman Aragaon AC, Veliz Peralta JA, Morales Lundes V, Hernandez Plata R, et al. Disgeusia como principal manifestacion oral en pacientes con covid-19 leve en el Instituto Nacional de Enfermedades Respiratorias. Odontol. Sammarquina 2022, 5(1): e22064 https.//doi.org/10.15381/osv25i1.22064 |
[9] | Herrera-Garcia JC, Areliano-Montellano EL, Juarez Gonzalez LI, Contreras-Andrade RI. Persistence of symptoms in patients after coronavirus disease (COVID-19) in a tertiary care hospital in Puebla. México. Med INtMex.2020; 36(6): 789-793. Available in: |
[10] | Nguyen NH, Hoag VI, Lagier J, Raoult D, Gautret P. Long- term persistence of olfactory and gustatory disorder in covid -19 patients. Clin Microbiol Infect.2021: 51198-743: 30. |
[11] | Brito –Zeron P, Conangla I, Kostov B, Moragas A, Ramos M, Seguiera F et al. Persistent manifestations of covid-19. Clinical practical quide [Internet] Barcelona: Catalan Society of Family and Community Medicine (CAMFIC), 2020. P1-43. Available in: |
[12] | Amdal CD. Heath-related Quality of Life’s Issues, Including Symptoms, in Patients with Active covid-19 or Post covid-19, a Systematic Literature Review Quality of Life Research.2021: 1-15. |
[13] | Veliz Villarruel FM, Asenjo Herrera CS. Frequency of symptoms of depression, generalized anxiety, and stress in post- COVID-19 patients at the Chacarato 2022 Health Center. Catholic University of Santamaria. Available in: https//:tesis.ucsm.edu.pe/repositorio/handle/20.500.12920/11737 |
[14] | Bruce Y, Villa P, Diaz A. Efectos Posteriores al covid-19. Revista Científica Cinectividad. https//doi.org/10.37431/conectividad.v3i127 |
[15] | Li J, Yang Z, Whang X, Dong L, et al. The psychological symptoms of patients whit mild’s symptoms of coronavirus diseases (2019) in China: A cross sectorial study. [Internet]. Vol.77. Journal of Advanced Nursing 2021. p.1813-24. Disponible en: |
[16] | Martinez Tejeda D. What is long-term COVID or post-COVID? Granma [Internet]. [cited 10 de Sep 2022]. Available in: |
[17] | Reyes Gonzalez ME. Neurological sequelae predominate in those recovered from COVID-19 IN Cuba [Internet]. Havana CNICM; 2021. [cited 18 de agosto 2022]. Available in: |
[18] | Andrade Tobar M, Garcia FE, Concha-Ponce P, Volunta C, Sucero C. (2021). Predictors of anxiety depression and stress symptoms following the COVID-19 epidemic outbreak. Journal of Psychopathology, 26(1), 13-22. |
[19] | Ministry of Public Health. Action protocol for convalescent COVID-19 patients in Primary Health Care. Havana; 2020. |
APA Style
Cobas, I. C., Diaz, M. G., Perez, S. A. (2025). Depression and Oral Manifestations Post-COVID19. American Journal of Nursing and Health Sciences, 6(4), 89-95. https://doi.org/10.11648/j.ajnhs.20250604.11
ACS Style
Cobas, I. C.; Diaz, M. G.; Perez, S. A. Depression and Oral Manifestations Post-COVID19. Am. J. Nurs. Health Sci. 2025, 6(4), 89-95. doi: 10.11648/j.ajnhs.20250604.11
@article{10.11648/j.ajnhs.20250604.11, author = {Ismaray Contreras Cobas and Madalaime Garcia Diaz and Surisaday Almeida Perez}, title = {Depression and Oral Manifestations Post-COVID19 }, journal = {American Journal of Nursing and Health Sciences}, volume = {6}, number = {4}, pages = {89-95}, doi = {10.11648/j.ajnhs.20250604.11}, url = {https://doi.org/10.11648/j.ajnhs.20250604.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajnhs.20250604.11}, abstract = {Introduction: The need for scientific literature relating post-COVID19 oral manifestations with depressive symptoms and the need to structure the variety of these and identify risk factors to prevent serious mental health affectations. Objective: To determine the relationship between oral manifestations and levels of depression in patients with post-COVID-19 sequels. Methods: A descriptive longitudinal study was carried out on 32 patients with mild COVID19 diseases, who persisted in their oral manifestations three months after diagnosis in the health area of the Marta Abreu Polyclinic, applying the Zung and Conde test to know their levels of depression. The statistical package SPSSv 21.0 and the chi-square test were used to process the data Results: In the research 81.2% of the patients present some level of depression, intervening the sociodemographic variable and if there is a significant relationship between the post-covid19 oral manifestations such as taste alteration and xerostomia with the appearance of emotional states such as depression. Conclusion: Post-COVID19 oral sequel can affect the emotional states influencing the level of depression of those who suffer from it. }, year = {2025} }
TY - JOUR T1 - Depression and Oral Manifestations Post-COVID19 AU - Ismaray Contreras Cobas AU - Madalaime Garcia Diaz AU - Surisaday Almeida Perez Y1 - 2025/10/14 PY - 2025 N1 - https://doi.org/10.11648/j.ajnhs.20250604.11 DO - 10.11648/j.ajnhs.20250604.11 T2 - American Journal of Nursing and Health Sciences JF - American Journal of Nursing and Health Sciences JO - American Journal of Nursing and Health Sciences SP - 89 EP - 95 PB - Science Publishing Group SN - 2994-7227 UR - https://doi.org/10.11648/j.ajnhs.20250604.11 AB - Introduction: The need for scientific literature relating post-COVID19 oral manifestations with depressive symptoms and the need to structure the variety of these and identify risk factors to prevent serious mental health affectations. Objective: To determine the relationship between oral manifestations and levels of depression in patients with post-COVID-19 sequels. Methods: A descriptive longitudinal study was carried out on 32 patients with mild COVID19 diseases, who persisted in their oral manifestations three months after diagnosis in the health area of the Marta Abreu Polyclinic, applying the Zung and Conde test to know their levels of depression. The statistical package SPSSv 21.0 and the chi-square test were used to process the data Results: In the research 81.2% of the patients present some level of depression, intervening the sociodemographic variable and if there is a significant relationship between the post-covid19 oral manifestations such as taste alteration and xerostomia with the appearance of emotional states such as depression. Conclusion: Post-COVID19 oral sequel can affect the emotional states influencing the level of depression of those who suffer from it. VL - 6 IS - 4 ER -