Arsenic and cadmium toxicity has demonstrated to be a crucial problem and there are many health issues interconnected with each other. The toxicity of these metals has no biological role even though remain present in some or the other form, hazardous for the human health and its proper functioning. As a result, from the very beginning, the researchers are trying to overcome the serious effects occurred by the heavy metals. The different procedures and methods are followed for minimizing the negative effects. The study was conducted to predict the probable effects and theirs targeted proteins in human body by recently developed advanced bioinformatics tools and subsequently found 10 proteins are interacted with arsenic and cadmium for each. However, these 10 proteins are independently associated with other 97 and 100 proteins. Finally, 25 common proteins have been identified which are affected by these two heavy metals. Our data mining search revealed that all of these 25 proteins are associated with the causing of cancer in human body.
| Published in | Computational Biology and Bioinformatics (Volume 5, Issue 6) |
| DOI | 10.11648/j.cbb.20170506.11 |
| Page(s) | 74-81 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Arsenic, Cadmium, Cancer, Interaction, Heavy Metals, Human Health
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APA Style
Md. Taif Ali, Md. Ashraful Alam, Md. Emdad Ullah, Mohammad Arif Ashraf, Md. Abu Sayed, et al. (2017). Prediction of Possible Effects of Arsenic and Cadmium in Human Health Using Chemical-Protein and Protein-Protein Interaction Network. Computational Biology and Bioinformatics, 5(6), 74-81. https://doi.org/10.11648/j.cbb.20170506.11
ACS Style
Md. Taif Ali; Md. Ashraful Alam; Md. Emdad Ullah; Mohammad Arif Ashraf; Md. Abu Sayed, et al. Prediction of Possible Effects of Arsenic and Cadmium in Human Health Using Chemical-Protein and Protein-Protein Interaction Network. Comput. Biol. Bioinform. 2017, 5(6), 74-81. doi: 10.11648/j.cbb.20170506.11
AMA Style
Md. Taif Ali, Md. Ashraful Alam, Md. Emdad Ullah, Mohammad Arif Ashraf, Md. Abu Sayed, et al. Prediction of Possible Effects of Arsenic and Cadmium in Human Health Using Chemical-Protein and Protein-Protein Interaction Network. Comput Biol Bioinform. 2017;5(6):74-81. doi: 10.11648/j.cbb.20170506.11
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Download@article{10.11648/j.cbb.20170506.11,
author = {Md. Taif Ali and Md. Ashraful Alam and Md. Emdad Ullah and Mohammad Arif Ashraf and Md. Abu Sayed and Aklima Jahan},
title = {Prediction of Possible Effects of Arsenic and Cadmium in Human Health Using Chemical-Protein and Protein-Protein Interaction Network},
journal = {Computational Biology and Bioinformatics},
volume = {5},
number = {6},
pages = {74-81},
doi = {10.11648/j.cbb.20170506.11},
url = {https://doi.org/10.11648/j.cbb.20170506.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cbb.20170506.11},
abstract = {Arsenic and cadmium toxicity has demonstrated to be a crucial problem and there are many health issues interconnected with each other. The toxicity of these metals has no biological role even though remain present in some or the other form, hazardous for the human health and its proper functioning. As a result, from the very beginning, the researchers are trying to overcome the serious effects occurred by the heavy metals. The different procedures and methods are followed for minimizing the negative effects. The study was conducted to predict the probable effects and theirs targeted proteins in human body by recently developed advanced bioinformatics tools and subsequently found 10 proteins are interacted with arsenic and cadmium for each. However, these 10 proteins are independently associated with other 97 and 100 proteins. Finally, 25 common proteins have been identified which are affected by these two heavy metals. Our data mining search revealed that all of these 25 proteins are associated with the causing of cancer in human body.},
year = {2017}
}
TY - JOUR T1 - Prediction of Possible Effects of Arsenic and Cadmium in Human Health Using Chemical-Protein and Protein-Protein Interaction Network AU - Md. Taif Ali AU - Md. Ashraful Alam AU - Md. Emdad Ullah AU - Mohammad Arif Ashraf AU - Md. Abu Sayed AU - Aklima Jahan Y1 - 2017/11/28 PY - 2017 N1 - https://doi.org/10.11648/j.cbb.20170506.11 DO - 10.11648/j.cbb.20170506.11 T2 - Computational Biology and Bioinformatics JF - Computational Biology and Bioinformatics JO - Computational Biology and Bioinformatics SP - 74 EP - 81 PB - Science Publishing Group SN - 2330-8281 UR - https://doi.org/10.11648/j.cbb.20170506.11 AB - Arsenic and cadmium toxicity has demonstrated to be a crucial problem and there are many health issues interconnected with each other. The toxicity of these metals has no biological role even though remain present in some or the other form, hazardous for the human health and its proper functioning. As a result, from the very beginning, the researchers are trying to overcome the serious effects occurred by the heavy metals. The different procedures and methods are followed for minimizing the negative effects. The study was conducted to predict the probable effects and theirs targeted proteins in human body by recently developed advanced bioinformatics tools and subsequently found 10 proteins are interacted with arsenic and cadmium for each. However, these 10 proteins are independently associated with other 97 and 100 proteins. Finally, 25 common proteins have been identified which are affected by these two heavy metals. Our data mining search revealed that all of these 25 proteins are associated with the causing of cancer in human body. VL - 5 IS - 6 ER -
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