The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs.
Published in | International Journal of Bioorganic Chemistry (Volume 7, Issue 1) |
DOI | 10.11648/j.ijbc.20220701.11 |
Page(s) | 1-10 |
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2022. Published by Science Publishing Group |
1,10-phenanthriline, Mixed Ligand Complexes, Biological Activities
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APA Style
Aklilu Melese Mengesha. (2022). The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands. International Journal of Bioorganic Chemistry, 7(1), 1-10. https://doi.org/10.11648/j.ijbc.20220701.11
ACS Style
Aklilu Melese Mengesha. The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands. Int. J. Bioorg. Chem. 2022, 7(1), 1-10. doi: 10.11648/j.ijbc.20220701.11
@article{10.11648/j.ijbc.20220701.11, author = {Aklilu Melese Mengesha}, title = {The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands}, journal = {International Journal of Bioorganic Chemistry}, volume = {7}, number = {1}, pages = {1-10}, doi = {10.11648/j.ijbc.20220701.11}, url = {https://doi.org/10.11648/j.ijbc.20220701.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbc.20220701.11}, abstract = {The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs.}, year = {2022} }
TY - JOUR T1 - The Study of Antimicrobial Activities of Various Transition Metal Mixed Ligand Complexes Containing 1,10-Phenanthroline with Any Other Ligands AU - Aklilu Melese Mengesha Y1 - 2022/02/28 PY - 2022 N1 - https://doi.org/10.11648/j.ijbc.20220701.11 DO - 10.11648/j.ijbc.20220701.11 T2 - International Journal of Bioorganic Chemistry JF - International Journal of Bioorganic Chemistry JO - International Journal of Bioorganic Chemistry SP - 1 EP - 10 PB - Science Publishing Group SN - 2578-9392 UR - https://doi.org/10.11648/j.ijbc.20220701.11 AB - The widespread usage of antibiotics in recent years has resulted in a surge in drug‑resistant bacteria resistant to a variety of medications. The identification of innovative and potent molecules against new targets is critical to combating the worrisome problem of microbial resistance to antibiotics. Numerous transition metal mixed ligand complexes have been explored as a result of this, with promising results. Because transition metals have different oxidation states and can interact with a variety of ligands, they play an essential role in medical inorganic chemistry. Metals' high activity has led to the recent creation of metal‑based pharmaceuticals that are being explored as viable candidates for pharmacological and therapeutic purposes. This review focuses on research conducted over the last few decades that has sought to possess biological applications such as antimicrobial, antifungal, and antibacterial activities of synthetic mixed ligand transition metal complexes, and it focuses primarily on a small number of transition metal mixed ligand complexes such as Mn (II), Co(II), Cu(II), and Zn(II), Ru(III) that contain 1,10-Phenanthroline as a major ligand The majority of this article is devoted to nitrogen donor ligands that chelate transition metals and are employed in metallodrugs. VL - 7 IS - 1 ER -