GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (<i>Cymbopogon citratus</i>)

Mahmoud Mohamed Ali; Mohammad Abdi Yusuf; Mohamed N. Abdalaziz

doi:doi:10.11648/j.ijpc.20170306.11

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GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus)

Mahmoud Mohamed Ali, Mohammad Abdi Yusuf, Mohamed N. Abdalaziz

Published in International Journal of Pharmacy and Chemistry (Volume 3, Issue 6)

Received: 29 September 2017 Accepted: 17 October 2017 Published: 1 November 2017

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Abstract

Medicinal plants are source of a great economic value. Plant herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Lemon grass was collected from administration gardens near Burjifartih west Khartoum, and was extracted for its oil by the hydro-distillation method approximately four hours. the extracted oil was analyzed by GC-MS and chemical constituents in the oil were identified, the major compounds in the oil were, citral (34.8%), neral (30.72%), β-myrecene (11.28%), geraniol (5.54%), 1,3,4-trimethyl 3-cyclohexene-1-Carboxaldehyde (2.20%), citonellol (1.34%). The compounds, D-Limonene (0.03%), Geranyl Acetate (0.57%) and Bicyclo [3.1.1] heptane-2-Carboxaldehyde-6,6-dimethyl (0.23%) were the minor compounds. antibacterial and antifungal activities of the oil were tested, all tested microorganisms were sensitive and no resistant was not observed, all growth inhibition zones occurred in the high activity level which is (>18mm).

Published in	International Journal of Pharmacy and Chemistry (Volume 3, Issue 6)
DOI	10.11648/j.ijpc.20170306.11
Page(s)	72-76
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Extraction, Lemon Grass, GC-MS, Antimicrobial

References

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[2]	Payne, G., Bringi, V., Prince, C. and Shuler, M. 1991. PlantCell and Tissue Culture in Liquid Systems. The Questfor Commercial Production of Chemicals from PlantCell Culture: 3. New York: Oxford University Press.
[3]	Kinsella, J. E. 1993. Possible mechanisms for the protective role of antioxidants in wine and plant foods. Food Technology: 85-89.
[4]	Terao, J. and Piskula, M. K. 1997. Flavonoids as inhibitors, The Journal of Physiology 555: 589-606.
[5]	Duthie, G. G. 1993. Lipid Peroxidation. European Journal of Clinical Nutrition 47(11):759-764.
[6]	Marles, R. and Farnsworth, N. 1994. Plants as sources of antidiabetic agents. In: Wagner, H.,Farnsworth, N. R.
[7]	Fields, M., Lewis, C. G. and Lure, M. D. 1996. Allopurinol, an Inhibitor of Xanthine Oxidase, Reduces Uric Acid Levels and Modifies the Signs Associated with Copper Deficiency in Rats Fed Fructose. Free Radical Biologyand Medicine 20 (4): 595 -600.
[8]	Kong L. D., Zhang Y., Pan X., Tan R. X. and ChengC. H. K. 2000. Inhibition of Xanthine Oxidase by Liquiritigenin and Isoliquiritigenin Isolated from Sino franch etiachinensi. Cellular and Molecular LifeSciences 57: 500-505.
[9]	Berry, C. E. and Hare, J. M. 2004. Xanthine Oxidoreductase and Cardiovascular Disease: The MolecularMechanisms and Pathophysiological Implications. The Journal of Physiology 555: 589-606.
[10]	Association of analytical chemistry(AOAC), 1990. Official methods of analysis of the association of official analytical chemists, 15th edition, page 951-952.
[11]	Akhila A.2010. Essential oil-bearing grasses: the genus Cymbopogon.
[12]	Kavanagh, F. (1972). Analytical microbiology. Vol. 11. Academic press (pub) New York and London. Pp 11.

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APA Style

Mahmoud Mohamed Ali, Mohammad Abdi Yusuf, Mohamed N. Abdalaziz. (2017). GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). International Journal of Pharmacy and Chemistry, 3(6), 72-76. https://doi.org/10.11648/j.ijpc.20170306.11

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ACS Style

Mahmoud Mohamed Ali; Mohammad Abdi Yusuf; Mohamed N. Abdalaziz. GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). Int. J. Pharm. Chem. 2017, 3(6), 72-76. doi: 10.11648/j.ijpc.20170306.11

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AMA Style

Mahmoud Mohamed Ali, Mohammad Abdi Yusuf, Mohamed N. Abdalaziz. GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). Int J Pharm Chem. 2017;3(6):72-76. doi: 10.11648/j.ijpc.20170306.11

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@article{10.11648/j.ijpc.20170306.11,
  author = {Mahmoud Mohamed Ali and Mohammad Abdi Yusuf and Mohamed N. Abdalaziz},
  title = {GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus)},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {3},
  number = {6},
  pages = {72-76},
  doi = {10.11648/j.ijpc.20170306.11},
  url = {https://doi.org/10.11648/j.ijpc.20170306.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20170306.11},
  abstract = {Medicinal plants are source of a great economic value. Plant herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Lemon grass was collected from administration gardens near Burjifartih west Khartoum, and was extracted for its oil by the hydro-distillation method approximately four hours. the extracted oil was analyzed by GC-MS and chemical constituents in the oil were identified, the major compounds in the oil were, citral (34.8%), neral (30.72%), β-myrecene (11.28%), geraniol (5.54%), 1,3,4-trimethyl 3-cyclohexene-1-Carboxaldehyde (2.20%), citonellol (1.34%). The compounds, D-Limonene (0.03%), Geranyl Acetate (0.57%) and Bicyclo [3.1.1] heptane-2-Carboxaldehyde-6,6-dimethyl (0.23%) were the minor compounds. antibacterial and antifungal activities of the oil were tested, all tested microorganisms were sensitive and no resistant was not observed, all growth inhibition zones occurred in the high activity level which is (>18mm).},
 year = {2017}
}

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TY  - JOUR
T1  - GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus)
AU  - Mahmoud Mohamed Ali
AU  - Mohammad Abdi Yusuf
AU  - Mohamed N. Abdalaziz
Y1  - 2017/11/01
PY  - 2017
N1  - https://doi.org/10.11648/j.ijpc.20170306.11
DO  - 10.11648/j.ijpc.20170306.11
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 72
EP  - 76
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20170306.11
AB  - Medicinal plants are source of a great economic value. Plant herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Lemon grass was collected from administration gardens near Burjifartih west Khartoum, and was extracted for its oil by the hydro-distillation method approximately four hours. the extracted oil was analyzed by GC-MS and chemical constituents in the oil were identified, the major compounds in the oil were, citral (34.8%), neral (30.72%), β-myrecene (11.28%), geraniol (5.54%), 1,3,4-trimethyl 3-cyclohexene-1-Carboxaldehyde (2.20%), citonellol (1.34%). The compounds, D-Limonene (0.03%), Geranyl Acetate (0.57%) and Bicyclo [3.1.1] heptane-2-Carboxaldehyde-6,6-dimethyl (0.23%) were the minor compounds. antibacterial and antifungal activities of the oil were tested, all tested microorganisms were sensitive and no resistant was not observed, all growth inhibition zones occurred in the high activity level which is (>18mm).
VL  - 3
IS  - 6
ER  -

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Author Information

Mahmoud Mohamed Ali

Department of Chemistry, Faculty of Pure and Applied Science, International University of Africa, Khartoum, Sudan
Mohammad Abdi Yusuf

Department of Chemistry, Faculty of Pure and Applied Science, International University of Africa, Khartoum, Sudan
Mohamed N. Abdalaziz

Department of Chemistry, Faculty of Pure and Applied Science, International University of Africa, Khartoum, Sudan

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APA Style

Mahmoud Mohamed Ali, Mohammad Abdi Yusuf, Mohamed N. Abdalaziz. (2017). GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). International Journal of Pharmacy and Chemistry, 3(6), 72-76. https://doi.org/10.11648/j.ijpc.20170306.11

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ACS Style

Mahmoud Mohamed Ali; Mohammad Abdi Yusuf; Mohamed N. Abdalaziz. GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). Int. J. Pharm. Chem. 2017, 3(6), 72-76. doi: 10.11648/j.ijpc.20170306.11

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AMA Style

Mahmoud Mohamed Ali, Mohammad Abdi Yusuf, Mohamed N. Abdalaziz. GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus). Int J Pharm Chem. 2017;3(6):72-76. doi: 10.11648/j.ijpc.20170306.11

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@article{10.11648/j.ijpc.20170306.11,
  author = {Mahmoud Mohamed Ali and Mohammad Abdi Yusuf and Mohamed N. Abdalaziz},
  title = {GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus)},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {3},
  number = {6},
  pages = {72-76},
  doi = {10.11648/j.ijpc.20170306.11},
  url = {https://doi.org/10.11648/j.ijpc.20170306.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20170306.11},
  abstract = {Medicinal plants are source of a great economic value. Plant herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Lemon grass was collected from administration gardens near Burjifartih west Khartoum, and was extracted for its oil by the hydro-distillation method approximately four hours. the extracted oil was analyzed by GC-MS and chemical constituents in the oil were identified, the major compounds in the oil were, citral (34.8%), neral (30.72%), β-myrecene (11.28%), geraniol (5.54%), 1,3,4-trimethyl 3-cyclohexene-1-Carboxaldehyde (2.20%), citonellol (1.34%). The compounds, D-Limonene (0.03%), Geranyl Acetate (0.57%) and Bicyclo [3.1.1] heptane-2-Carboxaldehyde-6,6-dimethyl (0.23%) were the minor compounds. antibacterial and antifungal activities of the oil were tested, all tested microorganisms were sensitive and no resistant was not observed, all growth inhibition zones occurred in the high activity level which is (>18mm).},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - GC-MS Analysis and Antimicrobial Screening of Essential Oil from Lemongrass (Cymbopogon citratus)
AU  - Mahmoud Mohamed Ali
AU  - Mohammad Abdi Yusuf
AU  - Mohamed N. Abdalaziz
Y1  - 2017/11/01
PY  - 2017
N1  - https://doi.org/10.11648/j.ijpc.20170306.11
DO  - 10.11648/j.ijpc.20170306.11
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 72
EP  - 76
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20170306.11
AB  - Medicinal plants are source of a great economic value. Plant herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Lemon grass was collected from administration gardens near Burjifartih west Khartoum, and was extracted for its oil by the hydro-distillation method approximately four hours. the extracted oil was analyzed by GC-MS and chemical constituents in the oil were identified, the major compounds in the oil were, citral (34.8%), neral (30.72%), β-myrecene (11.28%), geraniol (5.54%), 1,3,4-trimethyl 3-cyclohexene-1-Carboxaldehyde (2.20%), citonellol (1.34%). The compounds, D-Limonene (0.03%), Geranyl Acetate (0.57%) and Bicyclo [3.1.1] heptane-2-Carboxaldehyde-6,6-dimethyl (0.23%) were the minor compounds. antibacterial and antifungal activities of the oil were tested, all tested microorganisms were sensitive and no resistant was not observed, all growth inhibition zones occurred in the high activity level which is (>18mm).
VL  - 3
IS  - 6
ER  -

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