| Peer-Reviewed

Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine

Received: 26 March 2017     Accepted: 17 April 2017     Published: 10 July 2017
Views:       Downloads:
Abstract

The present study was designed to investigate the antioxidant activity of Solenostemma argel, Commiphora myrrha and Vernonia amygdaline. The antioxidant activities were conducted via DPPH radical scavenging and iron chelating assays. Potent antioxidant activity was presented by S. argel for both DPPH and iron chelating ability. The highest chelating ability was showed by the petroleum ether extract with 60%. The other tested plants showed low antioxidant potential. This study give rise to antioxidant property of S. argel.

Published in World Journal of Applied Chemistry (Volume 2, Issue 3)
DOI 10.11648/j.wjac.20170203.11
Page(s) 77-79
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Antioxidant, DPPH, Iron Chelating, Solenostemma Argel, Commiphora Myrrha, Vernonia Amygdaline

References
[1] Halliwell B., Gutteridge J (1989) in free radicals in Biology and Medicine, 2nd edtion Oxford University Press, Oxford, UK.
[2] Enns GM, Kinsman SL, Perlman SL, Spicer KM, Abdenur JE, et al. (2012) Initial experience in the treatment of inherited mitochondrial disease with EPI-743. Mol Genet Metab 105: 91-102.
[3] Skulachev VP, Anisimov VN, Antonenko YN, Bakeeva LE, Chernyak BV(2009) An attempt to prevent senescence: a mitochondrial approach. BiochimBiophysActa 1787: 437-461.
[4] Jomova K, Vondrakova D, Lawson M, Valko M (2010) Metals, oxidative stress and neurodegenerative disorders. Mol Cell Biochem 345: 91-104.
[5] Mariani E., Polidori MC., Cherubini A., Mecocci P (2005) Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B AnalytTechnol Biomed Life Sci, 827(1):65–75.
[6] Madeo J, Zubair A, Marianne F (2013). A review on the role of quinones in renal disorders. Springerplus 2: 139.
[7] Tsai KL, Chen LH, Chiou SH, Chiou GY, Chen YC, et al. (2011) Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. MolNutr Food Res 55 Suppl 2: S227-240.
[8] Morré DJ, Morré DM (2011) Non-mitochondrial coenzyme Q. Biofactors 37: 355-360.
[9] Karunakaran U, Park KG (2013) A systematic review of oxidative stress and safety of antioxidants in diabetes: focus on islets and their defense. Diabetes Metab J 37: 106-112.
[10] McCarty MF, Barroso-Aranda J, Contreras F (2010). Oxidative stress therapy for solid tumors - a proposal. Med Hypotheses 74: 1052-1054.
[11] Kurien BT, Scofield RH (2008) Autoimmunity and oxidatively modified autoantigens. Autoimmun Rev 7: 567-573.
[12] Frieri M (2012) Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches. Curr Allergy Asthma Rep 12: 25-32.
[13] Kritchevsky SB, Muldoon MF (1996). Oxidative stress and aging: still a hypothesis. J Am GeriatrSoc 44: 873-875.
[14] Sies H. (1997). Oxidative stress: oxidants and antioxidants. Exp. Physiol. 82(2): 291–295.
[15] Prerna U., Vikas S. (2010). Therapy of Alzheimer’s disease: An update. African Journal of Pharmacy and Pharmacology. 4,6, 408-421.
[16] Gareth Thomas (2007). Medicinal Chemistry. 2nd edition. John Wiley & Sons Ltd.
[17] Hema, T. A., Shiny, M. and Parvathy, J., (2012). Antimicrobial activity of leaves of Azimatetracantha against clinical pathogens. Int J PharmaSci 4(4):317-319.
[18] Prabhu GR., Gnanamani A and Sadulla S (2006). Guaijaverinaplant flavonoid as potential antiplaque agent against Streptococcus mutans. J. Applmicrobial.; 10: 487-95.
[19] Tiwari p, Kumar B, Kaur M, Kaur G and Kaur H (2011). Phytochemical screening and Extraction: A Review. Internationale Pharmaceutica Sciencia. 1, 98-106.
[20] Al- Deen AT and Al-Naqeb G (2014). Hypoglycemic effect and in vitro antioxidant activity of methanolic extract from Argel (Solenostemma Argel) plant. International Journal of Herbal Medicine. 2 (2): 128-131.
[21] Yeap SK, Ho WY, Beh BK, Liang WS, Ky H, Yousr AHN and Alitheen NB (2010). Vernoniaamygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bioactivities. Journal of Medicinal Plants Research. 4 (25): 2787-2812.
[22] Su S, Wang T, Chen T, Duan J, Yu L and Tang Y (2011). Cytotoxicity activity of extracts and compounds from Commiphoramyrrha resin against human gynecologic cancer cells. Journal of Medicinal Plants Research. 5(8): 1382-1389.
[23] Osama A and Awdelkarim S. Phytochemical screening of Ficussycomorus L. bark and Cleome gynandra L. aerial parts. J. Pharmacog. and Phytochem. 2015; 4(4): 24-27.
[24] Shimada K., Fujikawa K., Yahara K., Nakamura T. (1992) antioxidative properties of xanthan on the antioxidation of soybean oil in cyclodextrin emulsion. Journal of Agric food chemistry. 40:945-948.
[25] Dinis T, Madeira V, Almeida L, (1994) Action of phenolic derivates (acetoaminophen, salycilate, and 5-aminosalycilate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch BiochemBiophys. 315:161-169.
[26] Osama A, Awdelkarim S, Fadul E, Mohamed G, Siddig M, Sheikh A, Abdelmoneim A, Khalid A, Mohammed A (2015). In vitro Evaluation of Acacia nilotica Pods for its Antioxidant, Acetylcholinesterase Inhibitory Activities and Phytochemical Screening. Euro. Acad. Res. 3(3): 3059-3069.
Cite This Article
  • APA Style

    Sufyan Awadelkarim, Alsiddig Osama, Eltayeb Fadul. (2017). Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine. World Journal of Applied Chemistry, 2(3), 77-79. https://doi.org/10.11648/j.wjac.20170203.11

    Copy | Download

    ACS Style

    Sufyan Awadelkarim; Alsiddig Osama; Eltayeb Fadul. Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine. World J. Appl. Chem. 2017, 2(3), 77-79. doi: 10.11648/j.wjac.20170203.11

    Copy | Download

    AMA Style

    Sufyan Awadelkarim, Alsiddig Osama, Eltayeb Fadul. Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine. World J Appl Chem. 2017;2(3):77-79. doi: 10.11648/j.wjac.20170203.11

    Copy | Download

  • @article{10.11648/j.wjac.20170203.11,
      author = {Sufyan Awadelkarim and Alsiddig Osama and Eltayeb Fadul},
      title = {Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine},
      journal = {World Journal of Applied Chemistry},
      volume = {2},
      number = {3},
      pages = {77-79},
      doi = {10.11648/j.wjac.20170203.11},
      url = {https://doi.org/10.11648/j.wjac.20170203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjac.20170203.11},
      abstract = {The present study was designed to investigate the antioxidant activity of Solenostemma argel, Commiphora myrrha and Vernonia amygdaline. The antioxidant activities were conducted via DPPH radical scavenging and iron chelating assays. Potent antioxidant activity was presented by S. argel for both DPPH and iron chelating ability. The highest chelating ability was showed by the petroleum ether extract with 60%. The other tested plants showed low antioxidant potential. This study give rise to antioxidant property of S. argel.},
     year = {2017}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Antioxidant Evaluation of Three Sudanese Medicinal Plants Used in Traditional Medicine
    AU  - Sufyan Awadelkarim
    AU  - Alsiddig Osama
    AU  - Eltayeb Fadul
    Y1  - 2017/07/10
    PY  - 2017
    N1  - https://doi.org/10.11648/j.wjac.20170203.11
    DO  - 10.11648/j.wjac.20170203.11
    T2  - World Journal of Applied Chemistry
    JF  - World Journal of Applied Chemistry
    JO  - World Journal of Applied Chemistry
    SP  - 77
    EP  - 79
    PB  - Science Publishing Group
    SN  - 2637-5982
    UR  - https://doi.org/10.11648/j.wjac.20170203.11
    AB  - The present study was designed to investigate the antioxidant activity of Solenostemma argel, Commiphora myrrha and Vernonia amygdaline. The antioxidant activities were conducted via DPPH radical scavenging and iron chelating assays. Potent antioxidant activity was presented by S. argel for both DPPH and iron chelating ability. The highest chelating ability was showed by the petroleum ether extract with 60%. The other tested plants showed low antioxidant potential. This study give rise to antioxidant property of S. argel.
    VL  - 2
    IS  - 3
    ER  - 

    Copy | Download

Author Information
  • Department of Chemistry, Faculty of Science and Technology, Omdurman Islamic University, Khartoum, Sudan

  • Department of Chemistry, Faculty of Science and Technology, Omdurman Islamic University, Khartoum, Sudan

  • Medical Biochemistry Research Department, Medicinal and Aromatic Plants Research Institute, National Centre for Research, Khartoum, Sudan

  • Sections