Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification

Mohamed A. M. R. Afify; Ahmed H. Assaf; Raafat Ali Rehan; Hazem Abdallah Elnashar; Marwa A. Karim

doi:doi:10.11648/j.ijovs.20220702.12

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Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification

Mohamed A. M. R. Afify, Ahmed H. Assaf, Raafat Ali Rehan, Hazem Abdallah Elnashar, Marwa A. Karim

Published in International Journal of Ophthalmology & Visual Science (Volume 7, Issue 2)

Received: 7 April 2022 Accepted: 2 May 2022 Published: 7 May 2022

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Abstract

Aim: To assess corneal endothelium changes by non-contact specular microscopy in eyes underwent pars plana vitrectomy (PPV) with temporary silicone oil (SO) tamponade with or without phacoemulsification. Methods: We concluded 24 patients, divided to two groups: 12 patients had pars plana vitrectomy with SO injection (group 1) and 12 patients had combined phaco-vitrectomy with SO injection (group 2). All of them underwent full ophthalmological examination: best corrected visual acuity (BCVA), measurement of IOP, fundus examination and specular microscopy follow ups at the 1^st week, 1^st month and 3^rd month visits. Results: The count of Endothelial cell density (ECD) in group 1 dropped from 2543.58 ± 759.62 cell/mm², to 2299.33 ± 729.87 cell/mm², while in group 2 was 2621.08 ± 514.50, dropped to 2307.50 ± 575.55 respectively, and the mean cell density (MCD) decreased significantly in group 1 and group 2, at 3rd month than at 1st week. Three months after operation, CV (polymegathism) was 34.58 ± 4.29% and 35.75 ± 4.16%, hexagonality (pleomorphism) was 46.83 ± 8.67% and 47.83 ± 10.50%, while mean CCT was 553.08 ± 22.13 μm and 548.17 ± 33.12 for group 1 and 2 respectively, and without corneal edema reported at the study end. Conclusion: pleomorphism (decreased HEX), polymegathism (increased CV) and endothelial cell (EC) loss were documented in all patients underwent pars plana vitrectomy (PPV) with silicone oil (SO) injection with a higher probability of polymegathism (CV increase) noted after adding phacoemulsification to the procedure. These findings strongly suggest early SO removal after reaching aimed tamponading action to avoid SO keratopathy.

Published in	International Journal of Ophthalmology & Visual Science (Volume 7, Issue 2)
DOI	10.11648/j.ijovs.20220702.12
Page(s)	51-56
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Keratopathy, Silicon Tamponade, Phacovitrectomy, Corneal Endothelial Cells

References

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[16]	Michael A. Kass, Dale K. Heuer, Eve J. Higginbotham, et al. The Ocular Hypertension Treatment Study Randomized Trial Determines That Topical Ocular Hypotensive Medication Delays or Prevents the Onset of Primary Open-Angle Glaucoma Arch Ophthalmol. 2002; 120 (6): 701-713.
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APA Style

Mohamed A. M. R. Afify, Ahmed H. Assaf, Raafat Ali Rehan, Hazem Abdallah Elnashar, Marwa A. Karim. (2022). Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. International Journal of Ophthalmology & Visual Science, 7(2), 51-56. https://doi.org/10.11648/j.ijovs.20220702.12

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ACS Style

Mohamed A. M. R. Afify; Ahmed H. Assaf; Raafat Ali Rehan; Hazem Abdallah Elnashar; Marwa A. Karim. Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. Int. J. Ophthalmol. Vis. Sci. 2022, 7(2), 51-56. doi: 10.11648/j.ijovs.20220702.12

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AMA Style

Mohamed A. M. R. Afify, Ahmed H. Assaf, Raafat Ali Rehan, Hazem Abdallah Elnashar, Marwa A. Karim. Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. Int J Ophthalmol Vis Sci. 2022;7(2):51-56. doi: 10.11648/j.ijovs.20220702.12

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@article{10.11648/j.ijovs.20220702.12,
  author = {Mohamed A. M. R. Afify and Ahmed H. Assaf and Raafat Ali Rehan and Hazem Abdallah Elnashar and Marwa A. Karim},
  title = {Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {7},
  number = {2},
  pages = {51-56},
  doi = {10.11648/j.ijovs.20220702.12},
  url = {https://doi.org/10.11648/j.ijovs.20220702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20220702.12},
  abstract = {Aim: To assess corneal endothelium changes by non-contact specular microscopy in eyes underwent pars plana vitrectomy (PPV) with temporary silicone oil (SO) tamponade with or without phacoemulsification. Methods: We concluded 24 patients, divided to two groups: 12 patients had pars plana vitrectomy with SO injection (group 1) and 12 patients had combined phaco-vitrectomy with SO injection (group 2). All of them underwent full ophthalmological examination: best corrected visual acuity (BCVA), measurement of IOP, fundus examination and specular microscopy follow ups at the 1st week, 1st month and 3rd month visits. Results: The count of Endothelial cell density (ECD) in group 1 dropped from 2543.58 ± 759.62 cell/mm2, to 2299.33 ± 729.87 cell/mm2, while in group 2 was 2621.08 ± 514.50, dropped to 2307.50 ± 575.55 respectively, and the mean cell density (MCD) decreased significantly in group 1 and group 2, at 3rd month than at 1st week. Three months after operation, CV (polymegathism) was 34.58 ± 4.29% and 35.75 ± 4.16%, hexagonality (pleomorphism) was 46.83 ± 8.67% and 47.83 ± 10.50%, while mean CCT was 553.08 ± 22.13 μm and 548.17 ± 33.12 for group 1 and 2 respectively, and without corneal edema reported at the study end. Conclusion: pleomorphism (decreased HEX), polymegathism (increased CV) and endothelial cell (EC) loss were documented in all patients underwent pars plana vitrectomy (PPV) with silicone oil (SO) injection with a higher probability of polymegathism (CV increase) noted after adding phacoemulsification to the procedure. These findings strongly suggest early SO removal after reaching aimed tamponading action to avoid SO keratopathy.},
 year = {2022}
}

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TY  - JOUR
T1  - Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification
AU  - Mohamed A. M. R. Afify
AU  - Ahmed H. Assaf
AU  - Raafat Ali Rehan
AU  - Hazem Abdallah Elnashar
AU  - Marwa A. Karim
Y1  - 2022/05/07
PY  - 2022
N1  - https://doi.org/10.11648/j.ijovs.20220702.12
DO  - 10.11648/j.ijovs.20220702.12
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 51
EP  - 56
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20220702.12
AB  - Aim: To assess corneal endothelium changes by non-contact specular microscopy in eyes underwent pars plana vitrectomy (PPV) with temporary silicone oil (SO) tamponade with or without phacoemulsification. Methods: We concluded 24 patients, divided to two groups: 12 patients had pars plana vitrectomy with SO injection (group 1) and 12 patients had combined phaco-vitrectomy with SO injection (group 2). All of them underwent full ophthalmological examination: best corrected visual acuity (BCVA), measurement of IOP, fundus examination and specular microscopy follow ups at the 1st week, 1st month and 3rd month visits. Results: The count of Endothelial cell density (ECD) in group 1 dropped from 2543.58 ± 759.62 cell/mm2, to 2299.33 ± 729.87 cell/mm2, while in group 2 was 2621.08 ± 514.50, dropped to 2307.50 ± 575.55 respectively, and the mean cell density (MCD) decreased significantly in group 1 and group 2, at 3rd month than at 1st week. Three months after operation, CV (polymegathism) was 34.58 ± 4.29% and 35.75 ± 4.16%, hexagonality (pleomorphism) was 46.83 ± 8.67% and 47.83 ± 10.50%, while mean CCT was 553.08 ± 22.13 μm and 548.17 ± 33.12 for group 1 and 2 respectively, and without corneal edema reported at the study end. Conclusion: pleomorphism (decreased HEX), polymegathism (increased CV) and endothelial cell (EC) loss were documented in all patients underwent pars plana vitrectomy (PPV) with silicone oil (SO) injection with a higher probability of polymegathism (CV increase) noted after adding phacoemulsification to the procedure. These findings strongly suggest early SO removal after reaching aimed tamponading action to avoid SO keratopathy.
VL  - 7
IS  - 2
ER  -

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Author Information

Mohamed A. M. R. Afify

Memorial Institute for Ophthalmic Research (MIOR), Cairo, Egypt
Ahmed H. Assaf

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Raafat Ali Rehan

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Hazem Abdallah Elnashar

Memorial Institute for Ophthalmic Research (MIOR), Cairo, Egypt
Marwa A. Karim

Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

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APA Style

Mohamed A. M. R. Afify, Ahmed H. Assaf, Raafat Ali Rehan, Hazem Abdallah Elnashar, Marwa A. Karim. (2022). Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. International Journal of Ophthalmology & Visual Science, 7(2), 51-56. https://doi.org/10.11648/j.ijovs.20220702.12

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ACS Style

Mohamed A. M. R. Afify; Ahmed H. Assaf; Raafat Ali Rehan; Hazem Abdallah Elnashar; Marwa A. Karim. Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. Int. J. Ophthalmol. Vis. Sci. 2022, 7(2), 51-56. doi: 10.11648/j.ijovs.20220702.12

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AMA Style

Mohamed A. M. R. Afify, Ahmed H. Assaf, Raafat Ali Rehan, Hazem Abdallah Elnashar, Marwa A. Karim. Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification. Int J Ophthalmol Vis Sci. 2022;7(2):51-56. doi: 10.11648/j.ijovs.20220702.12

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@article{10.11648/j.ijovs.20220702.12,
  author = {Mohamed A. M. R. Afify and Ahmed H. Assaf and Raafat Ali Rehan and Hazem Abdallah Elnashar and Marwa A. Karim},
  title = {Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {7},
  number = {2},
  pages = {51-56},
  doi = {10.11648/j.ijovs.20220702.12},
  url = {https://doi.org/10.11648/j.ijovs.20220702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20220702.12},
  abstract = {Aim: To assess corneal endothelium changes by non-contact specular microscopy in eyes underwent pars plana vitrectomy (PPV) with temporary silicone oil (SO) tamponade with or without phacoemulsification. Methods: We concluded 24 patients, divided to two groups: 12 patients had pars plana vitrectomy with SO injection (group 1) and 12 patients had combined phaco-vitrectomy with SO injection (group 2). All of them underwent full ophthalmological examination: best corrected visual acuity (BCVA), measurement of IOP, fundus examination and specular microscopy follow ups at the 1st week, 1st month and 3rd month visits. Results: The count of Endothelial cell density (ECD) in group 1 dropped from 2543.58 ± 759.62 cell/mm2, to 2299.33 ± 729.87 cell/mm2, while in group 2 was 2621.08 ± 514.50, dropped to 2307.50 ± 575.55 respectively, and the mean cell density (MCD) decreased significantly in group 1 and group 2, at 3rd month than at 1st week. Three months after operation, CV (polymegathism) was 34.58 ± 4.29% and 35.75 ± 4.16%, hexagonality (pleomorphism) was 46.83 ± 8.67% and 47.83 ± 10.50%, while mean CCT was 553.08 ± 22.13 μm and 548.17 ± 33.12 for group 1 and 2 respectively, and without corneal edema reported at the study end. Conclusion: pleomorphism (decreased HEX), polymegathism (increased CV) and endothelial cell (EC) loss were documented in all patients underwent pars plana vitrectomy (PPV) with silicone oil (SO) injection with a higher probability of polymegathism (CV increase) noted after adding phacoemulsification to the procedure. These findings strongly suggest early SO removal after reaching aimed tamponading action to avoid SO keratopathy.},
 year = {2022}
}

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TY  - JOUR
T1  - Evaluation of Corneal Endothelial Changes in Eyes with Silicone Oil Tamponade After Pars Plana Vitrectomy with or Without Phacoemulsification
AU  - Mohamed A. M. R. Afify
AU  - Ahmed H. Assaf
AU  - Raafat Ali Rehan
AU  - Hazem Abdallah Elnashar
AU  - Marwa A. Karim
Y1  - 2022/05/07
PY  - 2022
N1  - https://doi.org/10.11648/j.ijovs.20220702.12
DO  - 10.11648/j.ijovs.20220702.12
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 51
EP  - 56
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20220702.12
AB  - Aim: To assess corneal endothelium changes by non-contact specular microscopy in eyes underwent pars plana vitrectomy (PPV) with temporary silicone oil (SO) tamponade with or without phacoemulsification. Methods: We concluded 24 patients, divided to two groups: 12 patients had pars plana vitrectomy with SO injection (group 1) and 12 patients had combined phaco-vitrectomy with SO injection (group 2). All of them underwent full ophthalmological examination: best corrected visual acuity (BCVA), measurement of IOP, fundus examination and specular microscopy follow ups at the 1st week, 1st month and 3rd month visits. Results: The count of Endothelial cell density (ECD) in group 1 dropped from 2543.58 ± 759.62 cell/mm2, to 2299.33 ± 729.87 cell/mm2, while in group 2 was 2621.08 ± 514.50, dropped to 2307.50 ± 575.55 respectively, and the mean cell density (MCD) decreased significantly in group 1 and group 2, at 3rd month than at 1st week. Three months after operation, CV (polymegathism) was 34.58 ± 4.29% and 35.75 ± 4.16%, hexagonality (pleomorphism) was 46.83 ± 8.67% and 47.83 ± 10.50%, while mean CCT was 553.08 ± 22.13 μm and 548.17 ± 33.12 for group 1 and 2 respectively, and without corneal edema reported at the study end. Conclusion: pleomorphism (decreased HEX), polymegathism (increased CV) and endothelial cell (EC) loss were documented in all patients underwent pars plana vitrectomy (PPV) with silicone oil (SO) injection with a higher probability of polymegathism (CV increase) noted after adding phacoemulsification to the procedure. These findings strongly suggest early SO removal after reaching aimed tamponading action to avoid SO keratopathy.
VL  - 7
IS  - 2
ER  -

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