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Clinical Neurology and Neuroscience

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Volume 6, Issue 2, June 2022

  • Insights into the Course of Illness of MS: Clinical and Radiological Aspects

    Roberto Bomprezzi, Andrew Chen, Christopher Hemond

    Issue: Volume 6, Issue 2, June 2022
    Pages: 19-28
    Received: 10 March 2022
    Accepted: 30 March 2022
    Published: 9 April 2022
    DOI: 10.11648/j.cnn.20220602.11
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    Abstract: Patients with MS manifest a high degree of variability in their disease course and at first glance the disease outcome may seem unpredictable. Here we present a framework for clinicians challenged by the management of MS patients and by highlighting important aspects of the disease to be taken into account, we review the complex relationship betwee... Show More
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  • Changes in Cortical Thickness Are Associated with Cognitive Impairments in Patients with White Matter Lesions

    Na Wei, Yufei Wei, Yuexiu Li, Decai Tian, Hongyan Chen, Yumei Zhang

    Issue: Volume 6, Issue 2, June 2022
    Pages: 29-36
    Received: 8 June 2022
    Accepted: 27 June 2022
    Published: 5 July 2022
    DOI: 10.11648/j.cnn.20220602.12
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    Abstract: White matter lesions (WMLs) are closely related with cognitive impairment and dementia. It has been hypothesized that cognitive impairment is related to cortical atrophy and cortical thickness network measurements in certain brain regions. We aimed to investigate the characteristics of cortical thickness in patients with WMLs and the relationship t... Show More
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