Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review

Shahela Tanveer; Vyshali Thakur; Shalabh Shrivastava; Nishath Ayesha

doi:doi:10.11648/j.advances.20220302.11

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Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review

Shahela Tanveer, Vyshali Thakur, Shalabh Shrivastava, Nishath Ayesha

Published in Advances (Volume 3, Issue 2)

Received: 31 January 2022 Accepted: 8 March 2022 Published: 20 April 2022

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Abstract

Adult mesenchymal stem cells (MSC’s) have a promising treatment in regenerative medicine from bone marrow transplant to current treatment of superceneterian cells in aging and progeria. There remains lot of regenerative aspect which are still in clinical trials in dentistry. Inspite of easy availability, remarkable capacity and efficient colony forming units of known oral stem cells there is limitation in using them in vivo, this remains an important aspect to use it clinically. The current review emphasizes on the quantification and characterization of inflamed stem cells from dental pulp and gingiva (I-DPSC’s and I-GMSC’s) which are commonly discarded tissue in dental treatment and the ability of these inflamed cells which are thought to maintain stemness over limited expansion in vitro and its capacity to display considerable phenotype and functional heterogeneity in par with healthy oral tissue as like with umblical tissue cells (UCB-MSCs) and adipose tissue (AT-MSCs) over bone marrow stem cells (BM-MSC’s).

Published in	Advances (Volume 3, Issue 2)
DOI	10.11648/j.advances.20220302.11
Page(s)	34-37
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

BM-MSC’s, I-DPSC’s, I-GMSC’s, UCB-MSC’s, AT-MSC’s

References

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[5]	G. T.- J. Huang, S. Gronthos, and S. Shi; Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources, Their Biology and Role in Regenerative Medicine. J Dent Res. 2009 Sep; 88 (9): 792–806.
[6]	Junjun L, Fang Y, Sun Y. Characteristics and Potential Applications of Human Dental Tissue-Derived Mesenchymal Stem Cell. STEM CELLS 2014.
[7]	Ana Gomes P, Hassan M, Francesco Guido M. Stem Cells in Dentistry: Types of Intra- and Extraoral Tissue-Derived Stem Cells and Clinical Applications. Hindawi. Stem cell research,. Volume 2018.
[8]	Susanne K, Hermann E, Johannes S. Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue. STEM CELLS 2006 Volume 24 (5): 1294-301.
[9]	Li hu, Jingquiong Hu et al. Side by side comparison of biological charecterstic of human ublical cord and adipose tissue derived mesenchymal stem cells. Biomed Res int. 2013.
[10]	Wolfgang W, Frederik W, Anja S. Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Stem cell biology November 2005, Vol 33, Issue 11: 1402-16.
[11]	Goodwin H S, Bicknese A R, Chien S N. Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant 2001; 7 (11): 581-8.
[12]	S Gronthos, M Mankani, J Brahim, P G Robey, S Shi; Postnatal Human Dental Pulp Stem Cells (DPSCs) in Vitro and in Vivo. Proc Natl Acad Sci U S A. 2000 Dec 5; 97 (25): 13625-30.
[13]	Jodie HarringtonAlastair J SloanAlastair J SloanRachel WaddingtonRachel Waddington Quantification of clonal heterogeneity of mesenchymal progenitor cells in dental pulp and bone marrow August 2014 Connective Tissue Research 55 (S1): 62-67.
[14]	Laura Tomasello, Rodolfo Mauceri, Antonina Coppola Mesenchymal stem cells derived from inflamed dental pulpal and gingival tissue: a potential application for bone formation Stem Cell Research & Therapy (2017) 8: 179.
[15]	Shaohua GeKrzysztof, MrozikDanijela, MenicaninDanijela Isolation and characterization of mesenchymal stem cell-like cells from healthy and inflamed gingival tissue: Potential use for clinical therapy. November 2012 Regenerative Medicine 7 (6): 819-32.
[16]	Nan Li Na Liu Jun Zhou Liang Tang Bofu Ding. Inflammatory environment induces gingival tissue-specific mesenchymal stem cells to differentiate towards a pro-fibrotic phenotype Biology of the CellVolume 105, Issue 6, 22 March 2013.
[17]	Hao Yang 1, Li-Na Gao, Ying An, Cheng-Hu. Comparison of mesenchymal stem cells derived from gingival tissue and periodontal ligament in different incubation conditions Biomaterials. 2013 Sep; 34 (29): 7033-47.
[18]	Dominick J Alongi, Takayoshi Yamaza, Yingjie Song Stem/progenitor cells from inflamed human dental pulp retain tissue regeneration potential. Regen. Med. (2010) 5 (4), 617–631.

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APA Style

Shahela Tanveer, Vyshali Thakur, Shalabh Shrivastava, Nishath Ayesha. (2022). Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances, 3(2), 34-37. https://doi.org/10.11648/j.advances.20220302.11

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ACS Style

Shahela Tanveer; Vyshali Thakur; Shalabh Shrivastava; Nishath Ayesha. Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances. 2022, 3(2), 34-37. doi: 10.11648/j.advances.20220302.11

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AMA Style

Shahela Tanveer, Vyshali Thakur, Shalabh Shrivastava, Nishath Ayesha. Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances. 2022;3(2):34-37. doi: 10.11648/j.advances.20220302.11

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@article{10.11648/j.advances.20220302.11,
  author = {Shahela Tanveer and Vyshali Thakur and Shalabh Shrivastava and Nishath Ayesha},
  title = {Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review},
  journal = {Advances},
  volume = {3},
  number = {2},
  pages = {34-37},
  doi = {10.11648/j.advances.20220302.11},
  url = {https://doi.org/10.11648/j.advances.20220302.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.advances.20220302.11},
  abstract = {Adult mesenchymal stem cells (MSC’s) have a promising treatment in regenerative medicine from bone marrow transplant to current treatment of superceneterian cells in aging and progeria. There remains lot of regenerative aspect which are still in clinical trials in dentistry. Inspite of easy availability, remarkable capacity and efficient colony forming units of known oral stem cells there is limitation in using them in vivo, this remains an important aspect to use it clinically. The current review emphasizes on the quantification and characterization of inflamed stem cells from dental pulp and gingiva (I-DPSC’s and I-GMSC’s) which are commonly discarded tissue in dental treatment and the ability of these inflamed cells which are thought to maintain stemness over limited expansion in vitro and its capacity to display considerable phenotype and functional heterogeneity in par with healthy oral tissue as like with umblical tissue cells (UCB-MSCs) and adipose tissue (AT-MSCs) over bone marrow stem cells (BM-MSC’s).},
 year = {2022}
}

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TY  - JOUR
T1  - Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review
AU  - Shahela Tanveer
AU  - Vyshali Thakur
AU  - Shalabh Shrivastava
AU  - Nishath Ayesha
Y1  - 2022/04/20
PY  - 2022
N1  - https://doi.org/10.11648/j.advances.20220302.11
DO  - 10.11648/j.advances.20220302.11
T2  - Advances
JF  - Advances
JO  - Advances
SP  - 34
EP  - 37
PB  - Science Publishing Group
SN  - 2994-7200
UR  - https://doi.org/10.11648/j.advances.20220302.11
AB  - Adult mesenchymal stem cells (MSC’s) have a promising treatment in regenerative medicine from bone marrow transplant to current treatment of superceneterian cells in aging and progeria. There remains lot of regenerative aspect which are still in clinical trials in dentistry. Inspite of easy availability, remarkable capacity and efficient colony forming units of known oral stem cells there is limitation in using them in vivo, this remains an important aspect to use it clinically. The current review emphasizes on the quantification and characterization of inflamed stem cells from dental pulp and gingiva (I-DPSC’s and I-GMSC’s) which are commonly discarded tissue in dental treatment and the ability of these inflamed cells which are thought to maintain stemness over limited expansion in vitro and its capacity to display considerable phenotype and functional heterogeneity in par with healthy oral tissue as like with umblical tissue cells (UCB-MSCs) and adipose tissue (AT-MSCs) over bone marrow stem cells (BM-MSC’s).
VL  - 3
IS  - 2
ER  -

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Author Information

Shahela Tanveer

Department of Oral Pathology, Sri Sai College of Dental Surgery, Hyderabad, India
Vyshali Thakur

General Practitioner Dental, Pune, Hyderabad, India
Shalabh Shrivastava

Department of Oral Pathology, Jaipur Dental College, Rajasthan, India
Nishath Ayesha

General Practitioner Dental, Saudia Dental Clinic, Riyadh, Saudia Arabia

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Plain Text BibTeX RIS

APA Style

Shahela Tanveer, Vyshali Thakur, Shalabh Shrivastava, Nishath Ayesha. (2022). Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances, 3(2), 34-37. https://doi.org/10.11648/j.advances.20220302.11

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ACS Style

Shahela Tanveer; Vyshali Thakur; Shalabh Shrivastava; Nishath Ayesha. Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances. 2022, 3(2), 34-37. doi: 10.11648/j.advances.20220302.11

Copy | Download

AMA Style

Shahela Tanveer, Vyshali Thakur, Shalabh Shrivastava, Nishath Ayesha. Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review. Advances. 2022;3(2):34-37. doi: 10.11648/j.advances.20220302.11

Copy | Download

@article{10.11648/j.advances.20220302.11,
  author = {Shahela Tanveer and Vyshali Thakur and Shalabh Shrivastava and Nishath Ayesha},
  title = {Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review},
  journal = {Advances},
  volume = {3},
  number = {2},
  pages = {34-37},
  doi = {10.11648/j.advances.20220302.11},
  url = {https://doi.org/10.11648/j.advances.20220302.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.advances.20220302.11},
  abstract = {Adult mesenchymal stem cells (MSC’s) have a promising treatment in regenerative medicine from bone marrow transplant to current treatment of superceneterian cells in aging and progeria. There remains lot of regenerative aspect which are still in clinical trials in dentistry. Inspite of easy availability, remarkable capacity and efficient colony forming units of known oral stem cells there is limitation in using them in vivo, this remains an important aspect to use it clinically. The current review emphasizes on the quantification and characterization of inflamed stem cells from dental pulp and gingiva (I-DPSC’s and I-GMSC’s) which are commonly discarded tissue in dental treatment and the ability of these inflamed cells which are thought to maintain stemness over limited expansion in vitro and its capacity to display considerable phenotype and functional heterogeneity in par with healthy oral tissue as like with umblical tissue cells (UCB-MSCs) and adipose tissue (AT-MSCs) over bone marrow stem cells (BM-MSC’s).},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Discarded and Inflammed Oral Stem Cells Shows Considerable Stemness Inspite of Lesser Yeild - A Systematic Review
AU  - Shahela Tanveer
AU  - Vyshali Thakur
AU  - Shalabh Shrivastava
AU  - Nishath Ayesha
Y1  - 2022/04/20
PY  - 2022
N1  - https://doi.org/10.11648/j.advances.20220302.11
DO  - 10.11648/j.advances.20220302.11
T2  - Advances
JF  - Advances
JO  - Advances
SP  - 34
EP  - 37
PB  - Science Publishing Group
SN  - 2994-7200
UR  - https://doi.org/10.11648/j.advances.20220302.11
AB  - Adult mesenchymal stem cells (MSC’s) have a promising treatment in regenerative medicine from bone marrow transplant to current treatment of superceneterian cells in aging and progeria. There remains lot of regenerative aspect which are still in clinical trials in dentistry. Inspite of easy availability, remarkable capacity and efficient colony forming units of known oral stem cells there is limitation in using them in vivo, this remains an important aspect to use it clinically. The current review emphasizes on the quantification and characterization of inflamed stem cells from dental pulp and gingiva (I-DPSC’s and I-GMSC’s) which are commonly discarded tissue in dental treatment and the ability of these inflamed cells which are thought to maintain stemness over limited expansion in vitro and its capacity to display considerable phenotype and functional heterogeneity in par with healthy oral tissue as like with umblical tissue cells (UCB-MSCs) and adipose tissue (AT-MSCs) over bone marrow stem cells (BM-MSC’s).
VL  - 3
IS  - 2
ER  -

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