Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases.
Published in | Biochemistry and Molecular Biology (Volume 2, Issue 6) |
DOI | 10.11648/j.bmb.20170206.13 |
Page(s) | 80-85 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2017. Published by Science Publishing Group |
Luffa acutangular, Phytochemical Constituents, Antimicrobial Activities, AAS, Proximate Analysis
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APA Style
Alagbe Seyi Valerie, Ibi Anna, Toge Christal, Amuzie Uzo Felicia, Ftepti Benson Jelani, et al. (2017). Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochemistry and Molecular Biology, 2(6), 80-85. https://doi.org/10.11648/j.bmb.20170206.13
ACS Style
Alagbe Seyi Valerie; Ibi Anna; Toge Christal; Amuzie Uzo Felicia; Ftepti Benson Jelani, et al. Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochem. Mol. Biol. 2017, 2(6), 80-85. doi: 10.11648/j.bmb.20170206.13
AMA Style
Alagbe Seyi Valerie, Ibi Anna, Toge Christal, Amuzie Uzo Felicia, Ftepti Benson Jelani, et al. Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochem Mol Biol. 2017;2(6):80-85. doi: 10.11648/j.bmb.20170206.13
@article{10.11648/j.bmb.20170206.13, author = {Alagbe Seyi Valerie and Ibi Anna and Toge Christal and Amuzie Uzo Felicia and Ftepti Benson Jelani and Raji Bamanga}, title = {Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts}, journal = {Biochemistry and Molecular Biology}, volume = {2}, number = {6}, pages = {80-85}, doi = {10.11648/j.bmb.20170206.13}, url = {https://doi.org/10.11648/j.bmb.20170206.13}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20170206.13}, abstract = {Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases.}, year = {2017} }
TY - JOUR T1 - Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts AU - Alagbe Seyi Valerie AU - Ibi Anna AU - Toge Christal AU - Amuzie Uzo Felicia AU - Ftepti Benson Jelani AU - Raji Bamanga Y1 - 2017/11/11 PY - 2017 N1 - https://doi.org/10.11648/j.bmb.20170206.13 DO - 10.11648/j.bmb.20170206.13 T2 - Biochemistry and Molecular Biology JF - Biochemistry and Molecular Biology JO - Biochemistry and Molecular Biology SP - 80 EP - 85 PB - Science Publishing Group SN - 2575-5048 UR - https://doi.org/10.11648/j.bmb.20170206.13 AB - Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases. VL - 2 IS - 6 ER -