@article{10.11648/j.ccr.20170102.15,
  author = {Mbarawa Kofia Ibrahim and Ngah Esther and Ndoe Guiaro Marcellin and Gilles Mache and Tamanji Marcel Nanji and Sitty Eguessa and Nwabo Kamdje Armel and Zofou Denis and Assob Nguedia},
  title = {Biological Investigation of the Benefits and Risk of Plants Consumed by Diabetics in Ngaoundere},
  journal = {Cardiology and Cardiovascular Research},
  volume = {1},
  number = {2},
  pages = {57-61},
  doi = {10.11648/j.ccr.20170102.15},
  url = {https://doi.org/10.11648/j.ccr.20170102.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20170102.15},
  abstract = {Medicinal plants have been reported as high risk of kidney failure among consumers. Around 80% in sub-Saharan population consume medicinal plants. This present study aimed to evaluate the influence of everyday life consumption of anti-diabetic plants among diabetic patients. We performed an analytical study in 54 participants. In diabetic population, we included 27 consumers of anti-diabetic plants and 27 non-consumers. We made the kidney screening with the measurement of the serum creatinine, urine creatinine, serum urea and fasting blood glucose. We estimated the GFR with the creatinine clearance of 24h. We used questionnaire to collect socio-demographic and personal history data. We identified 4 anti-diabetic plants used by our participants which are Leptadenie hastata, Detarium microcarpum, Boswellia dalzielii and Moringa oleifera. The average value of fasting blood glucose was low in patient consumers of plants (166 ± 43 mg/dl) than in non-consumers (229±53 mg/dl). We noted that consumers of Moringa oleifera (148.14±42 mg/dl) and Leptadenia hastata (148.25±46 mg/dl) presented best values of fasting blood glucose. We noted high prevalence of stage 3 and 4 of CKD in consumers of plant extracts (15%) than non-consumers (7%). Patient consumers of Detarium microcarpum and Boswellia dalzielii presented average value of eGFR in stage 2 of CKD. Though, consumers of Moringa oleifera and Leptadenia hastata presented healthy status of kidney function (116 ml/min/1.73m2 and 115 ml/min/1.73m2) followed by non-consumers group (102 ml/min/1.73m2). These results showed that Moringa oleifera and Leptadenia hastate are better anti-diabetic plants for management of diabetes and they could have nephron-protection effect among diabetics.},
 year = {2017}
}

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TY  - JOUR
T1  - Biological Investigation of the Benefits and Risk of Plants Consumed by Diabetics in Ngaoundere
AU  - Mbarawa Kofia Ibrahim
AU  - Ngah Esther
AU  - Ndoe Guiaro Marcellin
AU  - Gilles Mache
AU  - Tamanji Marcel Nanji
AU  - Sitty Eguessa
AU  - Nwabo Kamdje Armel
AU  - Zofou Denis
AU  - Assob Nguedia
Y1  - 2017/05/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ccr.20170102.15
DO  - 10.11648/j.ccr.20170102.15
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 57
EP  - 61
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20170102.15
AB  - Medicinal plants have been reported as high risk of kidney failure among consumers. Around 80% in sub-Saharan population consume medicinal plants. This present study aimed to evaluate the influence of everyday life consumption of anti-diabetic plants among diabetic patients. We performed an analytical study in 54 participants. In diabetic population, we included 27 consumers of anti-diabetic plants and 27 non-consumers. We made the kidney screening with the measurement of the serum creatinine, urine creatinine, serum urea and fasting blood glucose. We estimated the GFR with the creatinine clearance of 24h. We used questionnaire to collect socio-demographic and personal history data. We identified 4 anti-diabetic plants used by our participants which are Leptadenie hastata, Detarium microcarpum, Boswellia dalzielii and Moringa oleifera. The average value of fasting blood glucose was low in patient consumers of plants (166 ± 43 mg/dl) than in non-consumers (229±53 mg/dl). We noted that consumers of Moringa oleifera (148.14±42 mg/dl) and Leptadenia hastata (148.25±46 mg/dl) presented best values of fasting blood glucose. We noted high prevalence of stage 3 and 4 of CKD in consumers of plant extracts (15%) than non-consumers (7%). Patient consumers of Detarium microcarpum and Boswellia dalzielii presented average value of eGFR in stage 2 of CKD. Though, consumers of Moringa oleifera and Leptadenia hastata presented healthy status of kidney function (116 ml/min/1.73m2 and 115 ml/min/1.73m2) followed by non-consumers group (102 ml/min/1.73m2). These results showed that Moringa oleifera and Leptadenia hastate are better anti-diabetic plants for management of diabetes and they could have nephron-protection effect among diabetics.
VL  - 1
IS  - 2
ER  - 

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