Among hemodialysis (HD) patients, the left ventricular hypertrophy (LVH) is a common cardiovascular morbidity predictor. Ferritin level was considered as a clinical marker of iron storage and associated with cardiovascular mortality in chronic kidney disease (CKD) patients. The relationship between ferritin level and cardiac function in maintenance hemodialysis patients has not yet fully investigated. This study aimed to investigate the relationship between serum ferritin level and left ventricular mass index (LVMi) in hemodialysis patients. In this study, 70 regular chronic hemodialysis patients were included in a cross-sectional study (43 men and 27 women). The patients were sub-grouped into two groups according to the ferritin levels (patients with serum ferritin <800ng/ml (n=40), and patients with serum ferritin ≥800ng/ml (n=30)). Left ventricular mass (LVM), Left ventricular mass index (LVMi) and Left ventricular mass/hight 2.7 (LVM/Ht2.7) were evaluated by echocardiography. The patients with serum ferritin level ≥800 ng/ml showed significantly higher LVM, LVMI and LVM/Ht2.7 than other group. LVM, LVMI and LVM/Ht2.7 were significantly correlated to ferritin and hs-CRP. Regarding to the linear regression analysis, serum ferritin level was founded to be an independent predictors of LVM/Ht2.7 and but not for LVM nor LVMi. While, Highly sensitive C-reactive protein (hs-CRP) was founded to be independent predictors of LVM, LVMi and LVM/Ht2.7. This study showed that LVM, LVMI and LVM/ Ht2.7 are significantly elevated in patients with serum ferritin level ≥800 ng/ml. The serum ferritin was found to be independent predictors of LVH (represented by LVM/ Ht2.7) in maintenance HD patients.
| Published in | Cardiology and Cardiovascular Research (Volume 2, Issue 4) |
| DOI | 10.11648/j.ccr.20180204.15 |
| Page(s) | 98-103 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Left Ventricular Mass Index, Ferritin, Hemodialysis, Echocardiography
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APA Style
Ahmed Eldeeb, Ahmed Hosny El-Adawy, Elshahat Yousef, Ahmed Ibrahim, Mostafa Anis Mahmoud, et al. (2018). Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients. Cardiology and Cardiovascular Research, 2(4), 98-103. https://doi.org/10.11648/j.ccr.20180204.15
ACS Style
Ahmed Eldeeb; Ahmed Hosny El-Adawy; Elshahat Yousef; Ahmed Ibrahim; Mostafa Anis Mahmoud, et al. Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients. Cardiol. Cardiovasc. Res. 2018, 2(4), 98-103. doi: 10.11648/j.ccr.20180204.15
AMA Style
Ahmed Eldeeb, Ahmed Hosny El-Adawy, Elshahat Yousef, Ahmed Ibrahim, Mostafa Anis Mahmoud, et al. Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients. Cardiol Cardiovasc Res. 2018;2(4):98-103. doi: 10.11648/j.ccr.20180204.15
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author = {Ahmed Eldeeb and Ahmed Hosny El-Adawy and Elshahat Yousef and Ahmed Ibrahim and Mostafa Anis Mahmoud and Hany Abdel Shakour and Mohamed Omran},
title = {Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients},
journal = {Cardiology and Cardiovascular Research},
volume = {2},
number = {4},
pages = {98-103},
doi = {10.11648/j.ccr.20180204.15},
url = {https://doi.org/10.11648/j.ccr.20180204.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180204.15},
abstract = {Among hemodialysis (HD) patients, the left ventricular hypertrophy (LVH) is a common cardiovascular morbidity predictor. Ferritin level was considered as a clinical marker of iron storage and associated with cardiovascular mortality in chronic kidney disease (CKD) patients. The relationship between ferritin level and cardiac function in maintenance hemodialysis patients has not yet fully investigated. This study aimed to investigate the relationship between serum ferritin level and left ventricular mass index (LVMi) in hemodialysis patients. In this study, 70 regular chronic hemodialysis patients were included in a cross-sectional study (43 men and 27 women). The patients were sub-grouped into two groups according to the ferritin levels (patients with serum ferritin 2.7 (LVM/Ht2.7) were evaluated by echocardiography. The patients with serum ferritin level ≥800 ng/ml showed significantly higher LVM, LVMI and LVM/Ht2.7 than other group. LVM, LVMI and LVM/Ht2.7 were significantly correlated to ferritin and hs-CRP. Regarding to the linear regression analysis, serum ferritin level was founded to be an independent predictors of LVM/Ht2.7 and but not for LVM nor LVMi. While, Highly sensitive C-reactive protein (hs-CRP) was founded to be independent predictors of LVM, LVMi and LVM/Ht2.7. This study showed that LVM, LVMI and LVM/ Ht2.7 are significantly elevated in patients with serum ferritin level ≥800 ng/ml. The serum ferritin was found to be independent predictors of LVH (represented by LVM/ Ht2.7) in maintenance HD patients.},
year = {2018}
}
TY - JOUR T1 - Relation Between Serum Ferritin Level and the Left Ventricular Mass Index (LVMI) in Maintenance Hemodialysis Patients AU - Ahmed Eldeeb AU - Ahmed Hosny El-Adawy AU - Elshahat Yousef AU - Ahmed Ibrahim AU - Mostafa Anis Mahmoud AU - Hany Abdel Shakour AU - Mohamed Omran Y1 - 2018/12/19 PY - 2018 N1 - https://doi.org/10.11648/j.ccr.20180204.15 DO - 10.11648/j.ccr.20180204.15 T2 - Cardiology and Cardiovascular Research JF - Cardiology and Cardiovascular Research JO - Cardiology and Cardiovascular Research SP - 98 EP - 103 PB - Science Publishing Group SN - 2578-8914 UR - https://doi.org/10.11648/j.ccr.20180204.15 AB - Among hemodialysis (HD) patients, the left ventricular hypertrophy (LVH) is a common cardiovascular morbidity predictor. Ferritin level was considered as a clinical marker of iron storage and associated with cardiovascular mortality in chronic kidney disease (CKD) patients. The relationship between ferritin level and cardiac function in maintenance hemodialysis patients has not yet fully investigated. This study aimed to investigate the relationship between serum ferritin level and left ventricular mass index (LVMi) in hemodialysis patients. In this study, 70 regular chronic hemodialysis patients were included in a cross-sectional study (43 men and 27 women). The patients were sub-grouped into two groups according to the ferritin levels (patients with serum ferritin 2.7 (LVM/Ht2.7) were evaluated by echocardiography. The patients with serum ferritin level ≥800 ng/ml showed significantly higher LVM, LVMI and LVM/Ht2.7 than other group. LVM, LVMI and LVM/Ht2.7 were significantly correlated to ferritin and hs-CRP. Regarding to the linear regression analysis, serum ferritin level was founded to be an independent predictors of LVM/Ht2.7 and but not for LVM nor LVMi. While, Highly sensitive C-reactive protein (hs-CRP) was founded to be independent predictors of LVM, LVMi and LVM/Ht2.7. This study showed that LVM, LVMI and LVM/ Ht2.7 are significantly elevated in patients with serum ferritin level ≥800 ng/ml. The serum ferritin was found to be independent predictors of LVH (represented by LVM/ Ht2.7) in maintenance HD patients. VL - 2 IS - 4 ER -
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