Research Progress in Formation and Application of Tp-Te Interval

Baoxia Yue; Hui Tian; Biao Xu

doi:doi:10.11648/j.ccr.20190301.13

| Peer-Reviewed

Research Progress in Formation and Application of Tp-Te Interval

Baoxia Yue, Hui Tian, Biao Xu

Published in Cardiology and Cardiovascular Research (Volume 3, Issue 1)

Received: 2 January 2019 Accepted: 21 January 2019 Published: 19 February 2019

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Tp-Te interval refers to the duration from the peak to the end time points of T wave in electrocardiogram. Tp-Te interval is an electrocardiogram index reflecting mail-gnant ventricular arrhythmia, while Tp-Te interval mainly reflects ventricular transmural repolarization dispersion. The increase of ventricular transmural repolarization dispersion makes it easy to appear depolarization after repolarization, and forms functional conduction block between different regions, which leads to malignant arrhythmias. In this review we discuss how these markers have demonstrated to be effective to predict malignant arr- hythmias in medical conditions such as long and short QT syndromes, Brugada syndrome and so on. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients.

Published in	Cardiology and Cardiovascular Research (Volume 3, Issue 1)
DOI	10.11648/j.ccr.20190301.13
Page(s)	10-13
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Electrocardiographic Predictor, Ventricular Repolarization Markers, Ventricular Fibrillation, Sudden Cardiac Death, Tp-Te Interval

References

[1]	Zipes DP, Wellens HJ. Sudden cardiac death. Circulation 1998, 98: 2334-2351 [PMID]: 9826323.
[2]	Brugada R. La muerte súbita en el corazón sano. Rev Esp Cardiol 2010, 10: 78A-84A.
[3]	Kilicaslan F, Tokatli A, Ozdag F, et al. Tpeinterval, Tp-e/QT ratio, and Tp-e/QTc ratio are prolonged in patients with moderate and severe obstructive sleep apnea [J]. Pacing Clin Electrophysiol, 2012, 35 (8): 966-972.
[4]	Castro-Torres Y, Carmona-Puerta R, Katholi RE. Ventricular repolarization markers for predicting malignant arrhythmias in clinical practice. World J Clin Cases, 2015, 16; 3 (8): 705-720.
[5]	Dodd KW, Elm KD, Dodd EM, et al. Among patients with left bundle branch block, T-wave peak to T-wave end time is prolonged in the presence of acute coronary occlusion [J]. Int J Cardiol, 2017, 236:1-4.
[6]	Samol A, Gönes M, Zumhagen S, Bruns HJ, Paul M, Vahlhaus C, Waltenberger J, Schulze-Bahr E, Eckardt L, Mönnig G. Improved Clinical Risk Stratification in Patients with Long QT Syndrome? Novel Insights from Multi-Channel ECGs. PLo S One, 2016, 11 (7): e0158085.
[7]	Zumhagen S, Zeidler EM, Stallmeyer B, Ernsting M, Eckardt L, Schulze-Bahr E. Tpeak-Tend interval and Tpeak-Tend/QT ratio in patients with Brugada syndrome. Europace, 2016, 18 (12): 1866-1872.
[8]	Sanatani S, Whyte S. Normal Tp-Te values in children [J] Anesthesia & Analgesia, 2012, 114 (1): 240.
[9]	Rosenthal TM, Stahls PF 3rd, Abi Samra FM, et al. T-peak to T-end interval for prediction of ventricular tachya-rrhythmia and mortality in a primary prevention population with systolic cardiomyopathy [J] Heart Rhythm, 2015, 12 (8): 1789-1797.
[10]	Tse G, Gong M, Wong WT, et a. The Tpeak-Tend interval as an electrocardiographic risk marker of arrhythmic and mortality outcomes: A systematic review and meta-analysis [J] Heart Rhythm, 2017, 14 (8): 1131-1137.
[11]	Yamaguchi M, Shimizu M, Ino H, Terai H, Uchiyama K, Oe K, Mabuchi T, Konno T, Kaneda T, Mabuchi H. T wave peak-to-end interval and QT dispersion in acquired long QT syndrome: a new index for arrhythmogenicity. Clin Sci (Lond) 2003; 105: 671-676.
[12]	Bellocq C, van Ginneken AC, Bezzina CR, Alders M, Escande D, Mannens MM, Baró I, Wilde AA. Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation 2004, 109: 2394-2397.
[13]	Brugada R, Hong K, Dumaine R, Cordeiro J, Gaita F, Borggrefe M, Menendez TM, Brugada J, Pollevick GD, Wolpert C, Burashnikov E, Matsuo K, Wu YS, Guerchicoff A, Bianchi F, Giustetto C, Schimpf R, Brugada P, Antzelevitch C. Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation 2004, 109: 30-35.
[14]	Priori SG, Pandit SV, Rivolta I, Berenfeld O, Ronchetti E, Dhamoon A, Napolitano C, Anumonwo J, di Barletta MR, Gudapakkam S, Bosi G, Stramba-Badiale M, Jalife J. A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene. Circ Res 2005, 96: 800-807.
[15]	Castro Hevia J, Antzelevitch C, Tornés Bárzaga F, Dorantes Sánchez M, Dorticós Balea F, Zayas Molina R, Quiñones Pérez MA, Fayad Rodríguez Y. Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome. J Am Coll Cardiol 2006, 47:1828-1834.
[16]	Zumhagen S, Zeidler EM, Stallmeyer B, Ernsting M, Eckardt L, Schulze-Bahr E. Tpeak-Tend interval and Tpeak-Tend/QT ratio in patients with Brugada syndrome. Europace, 2016, 18 (12): 1866-1872.
[17]	Morita H, Watanabe A, Kawada S, et al. Identification of electrocardiographic risk markers for the initial and recurrent episodes of ventricular fibrillation in patients with Brugada syndrome [J]. J Cardiovasc Electrophysiol, 2018, 29 (1): 107-114.
[18]	Dogan M, Akyel A, Cimen T, et al. Relationship between neutrophil to lymphocyte ratio and slow coronary flow[J]. Clin Appl Thromb Hemost, 2015, 21: 251–254.
[19]	Kalay N, Aytekin M, Kaya MG, et al. The relationship between inflammation and slow coronary flow: increased red cell distribution width and serum uric acid levels [J]. Turk Kardiyol Dern Ars. 2011, 39: 463–468.
[20]	Tenekecioglu E, Karaagac K, Yontar OC, et al. Evaluation of Tp-Te Interval and Tp-Te /QT Ratio in Patients with Coronary Slow Flow Tp-Te/QTRatio and Coronary Slow Flow [J]. Eurasian J Med. 2015, 47 (2): 104-108.
[21]	Hetland M, Haugaa KH, Sarvari SI, et al. A novel ECG-index for prediction of ventricular arrhythmias in patients after myocardial infarction [J]. Ann Noninvasive Electrocardiol, 2014, 19 (4): 330-337.
[22]	Dodd KW, Elm KD, Dodd EM, et al. Among patients with left bundle branch block, T-wave peak to T-wave end time is prolonged in the presence of acute coronary occlusion [J]. Int J Cardiol, 2017, 236:1-4.
[23]	Shenthar J, Deora S, Rai M, et al. Prolonged Tpeak-end and Tpeak-end / QT ratio as predictors of malignant ventricular arrhythmias in the acute phase of ST- segment elevation myocardial infarction: a prospective case-controlstudy [J]. Heart Rhythm, 2015, 12 (3): 484-489.
[24]	Magrì D, Piccirillo G, Ricotta A, et al. Spatial QT Dispersion Predicts Nonsustained Ventricular Tachycardia and Correlates with Confined Systodiastolic Dysfunction in Hypertrophic Cardiomyopathy [J]. Cardiology, 2015, 131 (2): 122-129.
[25]	Akboğa MK, GÜlcihan Balc K, Yilmaz S, et al. Tp-Te interval and Tp-Te/QTc ratio as novel surrogate markers for prediction of ventricular arrhythmic events in hypertr ophic cardiomyopathy [J]. Anatol J Cardiol. 2017, 18 (1): 48-53.
[26]	Rautaharju PM, Zhang ZM, Haisty WK Jr, et al. Electrocardiographic predictors of incident Heart failure in men and women free from manifest cardiovascular disease (from the Atherosclerosis Risk in Communities [ARIC] study) [J]. Am J Cardiol, 2013, 112 (6):843-849.
[27]	Xue C, Hua W, Cai C, et al. Acute and Chronic Changes and Predictive Value of Tpeak-Tend for Ventricular Arrhythmia Risk in Cardiac Resynchronization Therapy Patients [J]. Chin Med J (Engl), 2016, 129 (18): 2204-2211.
[28]	Todd M. Rosenthal, Paul F. Stahls, Freddy M. Abi Samra, et al. T-peak to T-end interval for prediction of ventricular tachyarrhythmia and mortality in a primary prevention population with systolic cardiomyopathy. Heart Rhythm. 2015 Aug, 12 (8): 1789-97.

Cite This Article

Plain Text BibTeX RIS

APA Style

Baoxia Yue, Hui Tian, Biao Xu. (2019). Research Progress in Formation and Application of Tp-Te Interval. Cardiology and Cardiovascular Research, 3(1), 10-13. https://doi.org/10.11648/j.ccr.20190301.13

Copy | Download

ACS Style

Baoxia Yue; Hui Tian; Biao Xu. Research Progress in Formation and Application of Tp-Te Interval. Cardiol. Cardiovasc. Res. 2019, 3(1), 10-13. doi: 10.11648/j.ccr.20190301.13

Copy | Download

AMA Style

Baoxia Yue, Hui Tian, Biao Xu. Research Progress in Formation and Application of Tp-Te Interval. Cardiol Cardiovasc Res. 2019;3(1):10-13. doi: 10.11648/j.ccr.20190301.13

Copy | Download

@article{10.11648/j.ccr.20190301.13,
  author = {Baoxia Yue and Hui Tian and Biao Xu},
  title = {Research Progress in Formation and Application of Tp-Te Interval},
  journal = {Cardiology and Cardiovascular Research},
  volume = {3},
  number = {1},
  pages = {10-13},
  doi = {10.11648/j.ccr.20190301.13},
  url = {https://doi.org/10.11648/j.ccr.20190301.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20190301.13},
  abstract = {Tp-Te interval refers to the duration from the peak to the end time points of T wave in electrocardiogram. Tp-Te interval is an electrocardiogram index reflecting mail-gnant ventricular arrhythmia, while Tp-Te interval mainly reflects ventricular transmural repolarization dispersion. The increase of ventricular transmural repolarization dispersion makes it easy to appear depolarization after repolarization, and forms functional conduction block between different regions, which leads to malignant arrhythmias. In this review we discuss how these markers have demonstrated to be effective to predict malignant arr- hythmias in medical conditions such as long and short QT syndromes, Brugada syndrome and so on. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Research Progress in Formation and Application of Tp-Te Interval
AU  - Baoxia Yue
AU  - Hui Tian
AU  - Biao Xu
Y1  - 2019/02/19
PY  - 2019
N1  - https://doi.org/10.11648/j.ccr.20190301.13
DO  - 10.11648/j.ccr.20190301.13
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 10
EP  - 13
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20190301.13
AB  - Tp-Te interval refers to the duration from the peak to the end time points of T wave in electrocardiogram. Tp-Te interval is an electrocardiogram index reflecting mail-gnant ventricular arrhythmia, while Tp-Te interval mainly reflects ventricular transmural repolarization dispersion. The increase of ventricular transmural repolarization dispersion makes it easy to appear depolarization after repolarization, and forms functional conduction block between different regions, which leads to malignant arrhythmias. In this review we discuss how these markers have demonstrated to be effective to predict malignant arr- hythmias in medical conditions such as long and short QT syndromes, Brugada syndrome and so on. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients.
VL  - 3
IS  - 1
ER  -

Copy | Download

Author Information

Baoxia Yue

Department of Cardiology, Mudanjiang Medical University, Mudanjiang, China
Hui Tian

Department of Cardiology, Mudanjiang Medical University, Mudanjiang, China
Biao Xu

Department of Cardiology, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, China

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Baoxia Yue, Hui Tian, Biao Xu. (2019). Research Progress in Formation and Application of Tp-Te Interval. Cardiology and Cardiovascular Research, 3(1), 10-13. https://doi.org/10.11648/j.ccr.20190301.13

Copy | Download

ACS Style

Baoxia Yue; Hui Tian; Biao Xu. Research Progress in Formation and Application of Tp-Te Interval. Cardiol. Cardiovasc. Res. 2019, 3(1), 10-13. doi: 10.11648/j.ccr.20190301.13

Copy | Download

AMA Style

Baoxia Yue, Hui Tian, Biao Xu. Research Progress in Formation and Application of Tp-Te Interval. Cardiol Cardiovasc Res. 2019;3(1):10-13. doi: 10.11648/j.ccr.20190301.13

Copy | Download

@article{10.11648/j.ccr.20190301.13,
  author = {Baoxia Yue and Hui Tian and Biao Xu},
  title = {Research Progress in Formation and Application of Tp-Te Interval},
  journal = {Cardiology and Cardiovascular Research},
  volume = {3},
  number = {1},
  pages = {10-13},
  doi = {10.11648/j.ccr.20190301.13},
  url = {https://doi.org/10.11648/j.ccr.20190301.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20190301.13},
  abstract = {Tp-Te interval refers to the duration from the peak to the end time points of T wave in electrocardiogram. Tp-Te interval is an electrocardiogram index reflecting mail-gnant ventricular arrhythmia, while Tp-Te interval mainly reflects ventricular transmural repolarization dispersion. The increase of ventricular transmural repolarization dispersion makes it easy to appear depolarization after repolarization, and forms functional conduction block between different regions, which leads to malignant arrhythmias. In this review we discuss how these markers have demonstrated to be effective to predict malignant arr- hythmias in medical conditions such as long and short QT syndromes, Brugada syndrome and so on. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Research Progress in Formation and Application of Tp-Te Interval
AU  - Baoxia Yue
AU  - Hui Tian
AU  - Biao Xu
Y1  - 2019/02/19
PY  - 2019
N1  - https://doi.org/10.11648/j.ccr.20190301.13
DO  - 10.11648/j.ccr.20190301.13
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 10
EP  - 13
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20190301.13
AB  - Tp-Te interval refers to the duration from the peak to the end time points of T wave in electrocardiogram. Tp-Te interval is an electrocardiogram index reflecting mail-gnant ventricular arrhythmia, while Tp-Te interval mainly reflects ventricular transmural repolarization dispersion. The increase of ventricular transmural repolarization dispersion makes it easy to appear depolarization after repolarization, and forms functional conduction block between different regions, which leads to malignant arrhythmias. In this review we discuss how these markers have demonstrated to be effective to predict malignant arr- hythmias in medical conditions such as long and short QT syndromes, Brugada syndrome and so on. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients.
VL  - 3
IS  - 1
ER  -

Copy | Download