The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients

Ehab El-Hefny; Abdel Mageed Tag El-Din; Ayman Sadek; Eslam Abbas

doi:doi:10.11648/j.ccr.20200402.12

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The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients

Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas

Published in Cardiology and Cardiovascular Research (Volume 4, Issue 2)

Received: 28 February 2020 Accepted: 16 March 2020 Published: 21 April 2020

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Abstract

Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.

Published in	Cardiology and Cardiovascular Research (Volume 4, Issue 2)
DOI	10.11648/j.ccr.20200402.12
Page(s)	34-46
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Diabetic Retinopathy, Silent Myocardial Ischemia, Optical Coherence Tomography, Myocardial Perfusion Imaging

References

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Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas. (2020). The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiology and Cardiovascular Research, 4(2), 34-46. https://doi.org/10.11648/j.ccr.20200402.12

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ACS Style

Ehab El-Hefny; Abdel Mageed Tag El-Din; Ayman Sadek; Eslam Abbas. The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiol. Cardiovasc. Res. 2020, 4(2), 34-46. doi: 10.11648/j.ccr.20200402.12

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AMA Style

Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas. The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiol Cardiovasc Res. 2020;4(2):34-46. doi: 10.11648/j.ccr.20200402.12

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@article{10.11648/j.ccr.20200402.12,
  author = {Ehab El-Hefny and Abdel Mageed Tag El-Din and Ayman Sadek and Eslam Abbas},
  title = {The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients},
  journal = {Cardiology and Cardiovascular Research},
  volume = {4},
  number = {2},
  pages = {34-46},
  doi = {10.11648/j.ccr.20200402.12},
  url = {https://doi.org/10.11648/j.ccr.20200402.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20200402.12},
  abstract = {Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.},
 year = {2020}
}

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TY  - JOUR
T1  - The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients
AU  - Ehab El-Hefny
AU  - Abdel Mageed Tag El-Din
AU  - Ayman Sadek
AU  - Eslam Abbas
Y1  - 2020/04/21
PY  - 2020
N1  - https://doi.org/10.11648/j.ccr.20200402.12
DO  - 10.11648/j.ccr.20200402.12
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 34
EP  - 46
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20200402.12
AB  - Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.
VL  - 4
IS  - 2
ER  -

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Author Information

Ehab El-Hefny

Faculty of Medicine, Al Azhar University, Cairo, Egypt
Abdel Mageed Tag El-Din

Faculty of Medicine, Al Azhar University, Cairo, Egypt
Ayman Sadek

Faculty of Medicine, Al Azhar University, Cairo, Egypt
Eslam Abbas

Oncocardiology Department, Dar El Salam Cancer Center, Cairo, Egypt

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APA Style

Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas. (2020). The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiology and Cardiovascular Research, 4(2), 34-46. https://doi.org/10.11648/j.ccr.20200402.12

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ACS Style

Ehab El-Hefny; Abdel Mageed Tag El-Din; Ayman Sadek; Eslam Abbas. The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiol. Cardiovasc. Res. 2020, 4(2), 34-46. doi: 10.11648/j.ccr.20200402.12

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AMA Style

Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas. The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients. Cardiol Cardiovasc Res. 2020;4(2):34-46. doi: 10.11648/j.ccr.20200402.12

Copy | Download

@article{10.11648/j.ccr.20200402.12,
  author = {Ehab El-Hefny and Abdel Mageed Tag El-Din and Ayman Sadek and Eslam Abbas},
  title = {The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients},
  journal = {Cardiology and Cardiovascular Research},
  volume = {4},
  number = {2},
  pages = {34-46},
  doi = {10.11648/j.ccr.20200402.12},
  url = {https://doi.org/10.11648/j.ccr.20200402.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20200402.12},
  abstract = {Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.},
 year = {2020}
}

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TY  - JOUR
T1  - The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients
AU  - Ehab El-Hefny
AU  - Abdel Mageed Tag El-Din
AU  - Ayman Sadek
AU  - Eslam Abbas
Y1  - 2020/04/21
PY  - 2020
N1  - https://doi.org/10.11648/j.ccr.20200402.12
DO  - 10.11648/j.ccr.20200402.12
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 34
EP  - 46
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20200402.12
AB  - Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.
VL  - 4
IS  - 2
ER  -

Copy | Download