Background: Stress myocardial perfusion imaging (MPI) is a highly valuable test in the evaluation and risk stratification of ischemic heart disease. However, negative stress MPI does not exclude coronary atherosclerosis. The Coronary artery calcium (CAC) score is a validated simple test in the evaluation of coronary atherosclerosis. Our goal was to investigate the correlation between CAC score and Duke’s treadmill score, as well as the prevalence of CAC in patients with negative MPI. Methods: A total of 926 consecutive Egyptian patients, aged 30 to 60 years without known CAD, underwent CAC score testing following normal MPI. Results: In the setting of normal MPI among Egyptian patients without known CAD, mean age 48±7 years, 325 (35%) patients had a positive CAC score, and 9% had high CAC>100. Out of CAC>0, 160 were low-risk DTS. Our study showed no correlation between CAC score and DTS (P value=0.5). Age (OR=1.119, P value=<.001 and 95% confidence interval (CI)=1.071 - 1.169), male gender (OR=2.795, P value=.001 and 95% (CI)=1.494 - 5.230), and statin therapy (OR=2.020, P value=.008 and 95% (CI)=1.199 - 3.404), were significant independent predictors of a high CAC score>100. Conclusion: In a large number of normal MPI Egyptian patients without known CAD, CAC prevalence was 35%, confirming the beneficial value of adding CAC score test to negative MPI for cardiovascular risk stratification and screening for subclinical CAD regardless of DTS. Higher CAC values and prevalence were associated with age and male gender.
| Published in | Cardiology and Cardiovascular Research (Volume 5, Issue 4) |
| DOI | 10.11648/j.ccr.20210504.18 |
| Page(s) | 204-210 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
CAC Score, DTS, MPI
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APA Style
Abd Al Aziz Mohie Al Deen Abd Al Aziz, Mohamed Abou Mandour Ali, Ayman El Saeed Saddek, Adel Hassan Allam. (2021). Correlation Between Coronary Calcium Scoring and Duke’s Treadmill Score in Patients with Normal Myocardial Perfusion Imaging SPECT. Cardiology and Cardiovascular Research, 5(4), 204-210. https://doi.org/10.11648/j.ccr.20210504.18
ACS Style
Abd Al Aziz Mohie Al Deen Abd Al Aziz; Mohamed Abou Mandour Ali; Ayman El Saeed Saddek; Adel Hassan Allam. Correlation Between Coronary Calcium Scoring and Duke’s Treadmill Score in Patients with Normal Myocardial Perfusion Imaging SPECT. Cardiol. Cardiovasc. Res. 2021, 5(4), 204-210. doi: 10.11648/j.ccr.20210504.18
AMA Style
Abd Al Aziz Mohie Al Deen Abd Al Aziz, Mohamed Abou Mandour Ali, Ayman El Saeed Saddek, Adel Hassan Allam. Correlation Between Coronary Calcium Scoring and Duke’s Treadmill Score in Patients with Normal Myocardial Perfusion Imaging SPECT. Cardiol Cardiovasc Res. 2021;5(4):204-210. doi: 10.11648/j.ccr.20210504.18
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Download@article{10.11648/j.ccr.20210504.18,
author = {Abd Al Aziz Mohie Al Deen Abd Al Aziz and Mohamed Abou Mandour Ali and Ayman El Saeed Saddek and Adel Hassan Allam},
title = {Correlation Between Coronary Calcium Scoring and Duke’s Treadmill Score in Patients with Normal Myocardial Perfusion Imaging SPECT},
journal = {Cardiology and Cardiovascular Research},
volume = {5},
number = {4},
pages = {204-210},
doi = {10.11648/j.ccr.20210504.18},
url = {https://doi.org/10.11648/j.ccr.20210504.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20210504.18},
abstract = {Background: Stress myocardial perfusion imaging (MPI) is a highly valuable test in the evaluation and risk stratification of ischemic heart disease. However, negative stress MPI does not exclude coronary atherosclerosis. The Coronary artery calcium (CAC) score is a validated simple test in the evaluation of coronary atherosclerosis. Our goal was to investigate the correlation between CAC score and Duke’s treadmill score, as well as the prevalence of CAC in patients with negative MPI. Methods: A total of 926 consecutive Egyptian patients, aged 30 to 60 years without known CAD, underwent CAC score testing following normal MPI. Results: In the setting of normal MPI among Egyptian patients without known CAD, mean age 48±7 years, 325 (35%) patients had a positive CAC score, and 9% had high CAC>100. Out of CAC>0, 160 were low-risk DTS. Our study showed no correlation between CAC score and DTS (P value=0.5). Age (OR=1.119, P value=100. Conclusion: In a large number of normal MPI Egyptian patients without known CAD, CAC prevalence was 35%, confirming the beneficial value of adding CAC score test to negative MPI for cardiovascular risk stratification and screening for subclinical CAD regardless of DTS. Higher CAC values and prevalence were associated with age and male gender.},
year = {2021}
}
TY - JOUR T1 - Correlation Between Coronary Calcium Scoring and Duke’s Treadmill Score in Patients with Normal Myocardial Perfusion Imaging SPECT AU - Abd Al Aziz Mohie Al Deen Abd Al Aziz AU - Mohamed Abou Mandour Ali AU - Ayman El Saeed Saddek AU - Adel Hassan Allam Y1 - 2021/12/02 PY - 2021 N1 - https://doi.org/10.11648/j.ccr.20210504.18 DO - 10.11648/j.ccr.20210504.18 T2 - Cardiology and Cardiovascular Research JF - Cardiology and Cardiovascular Research JO - Cardiology and Cardiovascular Research SP - 204 EP - 210 PB - Science Publishing Group SN - 2578-8914 UR - https://doi.org/10.11648/j.ccr.20210504.18 AB - Background: Stress myocardial perfusion imaging (MPI) is a highly valuable test in the evaluation and risk stratification of ischemic heart disease. However, negative stress MPI does not exclude coronary atherosclerosis. The Coronary artery calcium (CAC) score is a validated simple test in the evaluation of coronary atherosclerosis. Our goal was to investigate the correlation between CAC score and Duke’s treadmill score, as well as the prevalence of CAC in patients with negative MPI. Methods: A total of 926 consecutive Egyptian patients, aged 30 to 60 years without known CAD, underwent CAC score testing following normal MPI. Results: In the setting of normal MPI among Egyptian patients without known CAD, mean age 48±7 years, 325 (35%) patients had a positive CAC score, and 9% had high CAC>100. Out of CAC>0, 160 were low-risk DTS. Our study showed no correlation between CAC score and DTS (P value=0.5). Age (OR=1.119, P value=100. Conclusion: In a large number of normal MPI Egyptian patients without known CAD, CAC prevalence was 35%, confirming the beneficial value of adding CAC score test to negative MPI for cardiovascular risk stratification and screening for subclinical CAD regardless of DTS. Higher CAC values and prevalence were associated with age and male gender. VL - 5 IS - 4 ER -
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