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Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study

Received: 14 March 2022     Accepted: 6 April 2022     Published: 20 April 2022
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Abstract

Background: Cardiovascular diseases (CVDs) are increasing worldwide with the greatest burden in low-income countries where there is a gradual epidemiologic transition from infectious diseases to non-communicable diseases. There is a paucity of data on CVDs in our setting. This study aims to describe the epidemiology, clinical, and therapeutic aspects of chronic coronary syndromes (CCS) in the Cameroonian cardiology setting to highlight the current state of practice to guide efficient epidemiological interventions. Methods: We retrospectively analyzed the records of patients hospitalized in two cardiology units of referral hospitals in the city of Yaoundé between 2010 and 2019 (10 years). Results: Of the 2756 records retrieved, 47 (1.7%) had CCS according to the 2019 European Society of Cardiology guidelines. The mean age was 58 ± 12 years and 63.8% were men. The most common cardiovascular risk factors were hypertension (78.7%), overweight or obesity (84.9%), dyslipidemias (80.9%), smoking (68.1%), and diabetes (67.7%). Chest pain on exertion (74.5%) and exertional dyspnea (70.2%) were the main symptoms. Repolarization disorders (83%) were the most frequent ECG signs. Sequelae of necrosis sequelae were found on ECG in 34% of cases and rhythm disorders in 21.3%. The therapeutic modalities were essentially anti-platelet (95.7%), statins (91.5%), beta-blockers (89.4%), and angiotensin-converting enzyme inhibitors (70.2%). Interventional treatments were rarely performed (2.1%). Conclusion: Although chronic coronary syndromes seem uncommon in cardiology hospitalization in Cameroon, public health policies must work to improve the current state of care particularly interventional care.

Published in Cardiology and Cardiovascular Research (Volume 6, Issue 2)
DOI 10.11648/j.ccr.20220602.11
Page(s) 50-54
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Epidemiology, Chronic Coronary Syndrome, Cameroon

References
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[2] Moran A, Forouzanfar M, Sampson U, Chugh S, Feigin V, Mensah G. The epidemiology of cardiovascular diseases in sub-Saharan Africa: the Global Burden of Diseases, Injuries and Risk Factors 2010 Study. Prog Cardiovasc Dis 2013; 56: 234–9. https://doi.org/10.1016/j.pcad.2013.09.019.
[3] Shahjehan RD, Bhutta BS. Coronary Artery Disease. StatPearls, Treasure Island (FL): StatPearls Publishing; 2021.
[4] Tuppin P, Rivière S, Rigault A, Tala S, Drouin J, Pestel L, et al. Prevalence and economic burden of cardiovascular diseases in France in 2013 according to the national health insurance scheme database. Arch Cardiovasc Dis 2016; 109: 399–411. https://doi.org/10.1016/j.acvd.2016.01.011.
[5] Prevalence of Coronary Heart Disease --- United States, 2006--2010 n.d. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6040a1.htm (accessed June 15, 2021).
[6] Cassar A, Holmes DR, Rihal CS, Gersh BJ. Chronic coronary artery disease: diagnosis and management. Mayo Clin Proc 2009; 84: 1130–46. https://doi.org/10.4065/mcp.2009.0391.
[7] Tantchou Tchoumi JC, Butera G. Profile of cardiac disease in Cameroon and impact on health care services. Cardiovasc Diagn Ther 2013; 3: 236–43. https://doi.org/10.3978/j.issn.2223-3652.2013.12.05.
[8] Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J 2020; 41: 407–77. https://doi.org/10.1093/eurheartj/ehz425.
[9] Yao H, Ekou A, Niamkey TJ, Soya EK, Aboley E, N’Guetta R. Lésions coronaires chez le noir africain dans les syndromes coronariens aigus. Pan Afr Med J 2019; 32. https://doi.org/10.11604/pamj.2019.32.104.12637.
[10] Steg PG, Greenlaw N, Tardif J-C, Tendera M, Ford I, Kääb S, et al. Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry. European Heart Journal 2012; 33: 2831–40. https://doi.org/10.1093/eurheartj/ehs289.
[11] Drissi A. Angiographic profile of ischemic heart disease in Rabat Hospital. Universite Mohammed V de Rabat, 2017.
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[13] Bamouni J, Naibe DT, Yameogo RA, Mandi DG, Millogo GRC, Yameogo NV, et al. Apport de l’épreuve d’effort dans la prise en charge des cardiopathies ischémiques. Pan Afr Med J 2018; 31. https://doi.org/10.11604/pamj.2018.31.229.15927.
[14] Task Force Members, Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C, et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013; 34: 2949–3003. https://doi.org/10.1093/eurheartj/eht296.
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Cite This Article
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    Liliane Mfeukeu-Kuate, Ba Hamadou, Jan René Nkeck, Ahmadou Musa Jingi, Albert Dipita Sosso, et al. (2022). Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study. Cardiology and Cardiovascular Research, 6(2), 50-54. https://doi.org/10.11648/j.ccr.20220602.11

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    ACS Style

    Liliane Mfeukeu-Kuate; Ba Hamadou; Jan René Nkeck; Ahmadou Musa Jingi; Albert Dipita Sosso, et al. Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study. Cardiol. Cardiovasc. Res. 2022, 6(2), 50-54. doi: 10.11648/j.ccr.20220602.11

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    AMA Style

    Liliane Mfeukeu-Kuate, Ba Hamadou, Jan René Nkeck, Ahmadou Musa Jingi, Albert Dipita Sosso, et al. Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study. Cardiol Cardiovasc Res. 2022;6(2):50-54. doi: 10.11648/j.ccr.20220602.11

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  • @article{10.11648/j.ccr.20220602.11,
      author = {Liliane Mfeukeu-Kuate and Ba Hamadou and Jan René Nkeck and Ahmadou Musa Jingi and Albert Dipita Sosso and Jerome Boombhi and Honoré Kemnang Yemele and Alain Patrick Menanga},
      title = {Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study},
      journal = {Cardiology and Cardiovascular Research},
      volume = {6},
      number = {2},
      pages = {50-54},
      doi = {10.11648/j.ccr.20220602.11},
      url = {https://doi.org/10.11648/j.ccr.20220602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20220602.11},
      abstract = {Background: Cardiovascular diseases (CVDs) are increasing worldwide with the greatest burden in low-income countries where there is a gradual epidemiologic transition from infectious diseases to non-communicable diseases. There is a paucity of data on CVDs in our setting. This study aims to describe the epidemiology, clinical, and therapeutic aspects of chronic coronary syndromes (CCS) in the Cameroonian cardiology setting to highlight the current state of practice to guide efficient epidemiological interventions. Methods: We retrospectively analyzed the records of patients hospitalized in two cardiology units of referral hospitals in the city of Yaoundé between 2010 and 2019 (10 years). Results: Of the 2756 records retrieved, 47 (1.7%) had CCS according to the 2019 European Society of Cardiology guidelines. The mean age was 58 ± 12 years and 63.8% were men. The most common cardiovascular risk factors were hypertension (78.7%), overweight or obesity (84.9%), dyslipidemias (80.9%), smoking (68.1%), and diabetes (67.7%). Chest pain on exertion (74.5%) and exertional dyspnea (70.2%) were the main symptoms. Repolarization disorders (83%) were the most frequent ECG signs. Sequelae of necrosis sequelae were found on ECG in 34% of cases and rhythm disorders in 21.3%. The therapeutic modalities were essentially anti-platelet (95.7%), statins (91.5%), beta-blockers (89.4%), and angiotensin-converting enzyme inhibitors (70.2%). Interventional treatments were rarely performed (2.1%). Conclusion: Although chronic coronary syndromes seem uncommon in cardiology hospitalization in Cameroon, public health policies must work to improve the current state of care particularly interventional care.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Epidemiology, Clinical, and Therapeutic Aspects of Chronic Coronary Syndromes in Yaounde-Cameroon: A 10-year Cross-sectional Study
    AU  - Liliane Mfeukeu-Kuate
    AU  - Ba Hamadou
    AU  - Jan René Nkeck
    AU  - Ahmadou Musa Jingi
    AU  - Albert Dipita Sosso
    AU  - Jerome Boombhi
    AU  - Honoré Kemnang Yemele
    AU  - Alain Patrick Menanga
    Y1  - 2022/04/20
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ccr.20220602.11
    DO  - 10.11648/j.ccr.20220602.11
    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
    JO  - Cardiology and Cardiovascular Research
    SP  - 50
    EP  - 54
    PB  - Science Publishing Group
    SN  - 2578-8914
    UR  - https://doi.org/10.11648/j.ccr.20220602.11
    AB  - Background: Cardiovascular diseases (CVDs) are increasing worldwide with the greatest burden in low-income countries where there is a gradual epidemiologic transition from infectious diseases to non-communicable diseases. There is a paucity of data on CVDs in our setting. This study aims to describe the epidemiology, clinical, and therapeutic aspects of chronic coronary syndromes (CCS) in the Cameroonian cardiology setting to highlight the current state of practice to guide efficient epidemiological interventions. Methods: We retrospectively analyzed the records of patients hospitalized in two cardiology units of referral hospitals in the city of Yaoundé between 2010 and 2019 (10 years). Results: Of the 2756 records retrieved, 47 (1.7%) had CCS according to the 2019 European Society of Cardiology guidelines. The mean age was 58 ± 12 years and 63.8% were men. The most common cardiovascular risk factors were hypertension (78.7%), overweight or obesity (84.9%), dyslipidemias (80.9%), smoking (68.1%), and diabetes (67.7%). Chest pain on exertion (74.5%) and exertional dyspnea (70.2%) were the main symptoms. Repolarization disorders (83%) were the most frequent ECG signs. Sequelae of necrosis sequelae were found on ECG in 34% of cases and rhythm disorders in 21.3%. The therapeutic modalities were essentially anti-platelet (95.7%), statins (91.5%), beta-blockers (89.4%), and angiotensin-converting enzyme inhibitors (70.2%). Interventional treatments were rarely performed (2.1%). Conclusion: Although chronic coronary syndromes seem uncommon in cardiology hospitalization in Cameroon, public health policies must work to improve the current state of care particularly interventional care.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

  • Faculty of Health Sciences, University of Bamenda, Bamenda, Cameroon

  • Higher Institute of Health Sciences, Université de Montagne, Banganté, Cameroon

  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

  • Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon

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