Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)

Yuki Matsui; Wahei Yanagida; Jun Morita; Takashi Fukagai

doi:doi:10.11648/j.ijcu.20250901.13

Research Article |

| Peer-Reviewed

Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)

Yuki Matsui^*

, Wahei Yanagida

, Jun Morita

, Takashi Fukagai

Published in International Journal of Clinical Urology (Volume 9, Issue 1)

Received: 23 December 2024 Accepted: 13 January 2025 Published: 24 January 2025

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Objective: This study aimed to compare short-term quality of life (QOL) outcomes and perioperative parameters between transurethral resection of the prostate (TURP) and thulium laser vaporization of the prostate (ThuVap) in patients with benign prostatic hyperplasia (BPH). Materials and Methods: A retrospective analysis was conducted on 106 patients with BPH who underwent either TURP (n = 58) or ThuVap (n = 48) at our institution between April 2021 and August 2024. Preoperative and postoperative evaluations included the International Prostate Symptom Score (I-PSS), Overactive Bladder Symptom Score (OABSS), QOL index, and uroflowmetry. Perioperative outcomes, including operative time, catheterization duration, and hemoglobin (Hb) reduction, were also analyzed. Results: Both TURP and ThuVap showed sustained improvements in I-PSS, OABSS, and QOL index during the 3-month follow-up period, with no significant differences between the groups. ThuVap demonstrated a significantly lower rate of Hb reduction on the first postoperative day compared to TURP (5.9% vs. 8.5%, P < 0.05), likely due to reduced intraoperative bleeding. Although ThuVap had a shorter mean operative time (82.3 vs. 99.3 minutes), this difference was not statistically significant (P = 0.1). Discussion: The findings indicate that both TURP and ThuVap effectively improve postoperative QOL. ThuVap's reduced bleeding may provide advantages in patients with higher cardiovascular or bleeding risks. However, variations in operative time between studies may be influenced by factors such as surgeons' experience and institutional protocols. Conclusion: Both TURP and ThuVap are effective surgical options for improving QOL in BPH patients. However, surgical efficiency and outcomes may be influenced by the surgeon's expertise and the preoperative condition of the patients. ThuVap offers additional benefits of reduced intraoperative bleeding, which may support its use in selected cases.

Published in	International Journal of Clinical Urology (Volume 9, Issue 1)
DOI	10.11648/j.ijcu.20250901.13
Page(s)	13-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Thulium Laser Vaporization, Quality of Life, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms

References

[1]	S J Berry, D S Coffey, P C Walsh, et al. The development of human benign prostatic hyperplasia with age. J Urol. 1984 Sep; 132(3): 474-9. https://doi.org/10.1016/s0022-5347(17)49698-4
[2]	Narihito Seki, Takakazu Yunoki, Toshihisa Tomoda. et al. Association among the symptoms, quality of life and urodynamic parameters in patients with improved lower urinary tract symptoms following a transurethral resection of the prostate. Neurourol Urodyn. 2008; 27(3): 222-5. https://doi.org/10.1002/nau.20466
[3]	Jean-Nicolas Cornu. Bipolar, Monopolar, Photovaporization of the Prostate, or Holmium Laser Enucleation of the Prostate: How to Choose What's Best? Urol Clin North Am. 2016 Aug; 43(3). https://doi.org/10.1016/j.ucl.2016.04.006
[4]	Chyng-Wen Fwu, Paul W Eggers, Steven A Kaplan. et al. Long-term effects of doxazosin, finasteride and combination therapy on quality of life in men with benign prostatic hyperplasia. J Urol. 2013 Jul; 190(1): 187-93. https://doi.org/10.1016/j.juro.2013.01.061
[5]	Maral DerSarkissian, Yongling Xiao, Mei Sheng Duh. et al. Comparing Clinical and Economic Outcomes Associated with Early Initiation of Combination Therapy of an Alpha Blocker and Dutasteride or Finasteride in Men with Benign Prostatic Hyperplasia in the United States. J Manag Care Spec Pharm. 2016 Oct; 22(10). https://doi.org/10.18553/jmcp.2016.22.10.1204
[6]	W M Garraway, R S Kirby. Benign prostatic hyperplasia: effects on quality of life and impact on treatment decisions. Urology. 1994 Nov; 44(5): 629-36. https://doi.org/10.1016/s0090-4295(94)80194-0
[7]	Bob Djavan, Elisabeth Eckersberger, Julia Finkelstein. et al. Benign prostatic hyperplasia: current clinical practice. Prim Care. 2010 Sep; 37(3): 583-97. https://doi.org/10.1016/j.pop.2010.04.004
[8]	Richard Naspro, Fernando Gomez Sancha, Michele Manica. et al. From "gold standard" resection to reproducible "future standard" endoscopic enucleation of the prostate: what we know about anatomical enucleation. Minerva Urol Nefrol. 2017 Oct; 69(5): 446-458. https://doi.org/10.23736/S0393-2249.17.02834-X
[9]	Tatsunori Okada, Mikifumi Koura, Ryota Sumikawa. et al. A prospective, single-center, randomized clinical trial to evaluate the efficacy of three types of laser vaporization surgeries using a 180-W GreenLight XPS laser, a 300-W diode laser, and a 200-W thulium laser for the treatment of benign prostatic hyperplasia. Low Urin Tract Symptoms. 2022 Sep; 14(5): 373-379. https://doi.org/10.1111/luts.12453
[10]	Aldo Brassetti, Cosimo DE Nunzio, Nicolas B Delongchamps. et al. Green light vaporization of the prostate: is it an adult technique? Minerva Urol Nefrol. 2017 Apr; 69(2): 109-118. https://doi.org/10.23736/S0393-2249.16.02791-0
[11]	Stephan Madersbacher, Gerasimos Alivizatos, Jorgen Nordling. et al. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). Eur Urol. 2004 Nov; 46(5): 547-54. https://doi.org/10.1016/j.eururo.2004.07.016
[12]	Jean-Nicolas Cornu, Sascha Ahyai, Alexander Bachmann. et al. A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update. Eur Urol. 2015 Jun; 67(6): 1066-1096. https://doi.org/10.1016/j.eururo.2014.06.017
[13]	Ya-Chen Zang, Xin-Xi Deng, Dong-Rong Yang. et al. Photoselective vaporization of the prostate with GreenLight 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis of randomized controlled trials. Lasers Med Sci. 2016 Feb; 31(2): 235-40. https://doi.org/10.1007/s10103-015-1843-1
[14]	Yu Lan, Wenqi Wu, Luhao Liu, et al. Thulium (Tm:YAG) laser vaporesection of prostate and bipolar transurethral resection of prostate in patients with benign prostate hyperplasia: a systematic review and meta-analysis. Lasers Med Sci. 2018 Sep; 33(7): 1411-1421. https://doi.org/10.1007/s10103-018-2539-0
[15]	Grégoire Robert, Jean-Nicolas Cornu, Marc Fourmarier et al. Multicentre prospective evaluation of the learning curve of holmium laser enucleation of the prostate (HoLEP). BJU Int. 2016 Mar; 117(3): 495-9. https://doi.org/10.1111/bju.13124
[16]	Spyridon Kampantais, Panagiotis Dimopoulos, Ali Tasleem. et al. Assessing the Learning Curve of Holmium Laser Enucleation of Prostate (HoLEP). A Systematic Review. Urology. 2018 Oct: 120: 9-22. https://doi.org/10.1016/j.urology.2018.06.012
[17]	Pietro Castellan, Michele Marchioni, Ambra Rizzoli. et al. The Surgical Experience Influences the Safety and Efficacy of Photovaporization of Prostate with 180-W XPS GreenLight Laser: Comparison Between Novices vs Expert Surgeons Learning Curves. J Endourol. 2018 Nov; 32(11): 1071-1077. https://doi.org/10.1089/end.2018.0437
[18]	Inyoung un, angjunYoo, Juhyun ark. et al. Quality of life after photo-selective vaporization and holmium-laser enucleation of the prostate: 5-year outcomes. Sci Rep. 2019 Jun 4; 9(1): 8261. https://doi.org/10.1038/s41598-019-44686-2

Cite This Article

Plain Text BibTeX RIS

APA Style

Matsui, Y., Yanagida, W., Morita, J., Fukagai, T. (2025). Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). International Journal of Clinical Urology, 9(1), 13-19. https://doi.org/10.11648/j.ijcu.20250901.13

Copy | Download

ACS Style

Matsui, Y.; Yanagida, W.; Morita, J.; Fukagai, T. Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). Int. J. Clin. Urol. 2025, 9(1), 13-19. doi: 10.11648/j.ijcu.20250901.13

Copy | Download

AMA Style

Matsui Y, Yanagida W, Morita J, Fukagai T. Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). Int J Clin Urol. 2025;9(1):13-19. doi: 10.11648/j.ijcu.20250901.13

Copy | Download

@article{10.11648/j.ijcu.20250901.13,
  author = {Yuki Matsui and Wahei Yanagida and Jun Morita and Takashi Fukagai},
  title = {Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)
},
  journal = {International Journal of Clinical Urology},
  volume = {9},
  number = {1},
  pages = {13-19},
  doi = {10.11648/j.ijcu.20250901.13},
  url = {https://doi.org/10.11648/j.ijcu.20250901.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20250901.13},
  abstract = {Objective: This study aimed to compare short-term quality of life (QOL) outcomes and perioperative parameters between transurethral resection of the prostate (TURP) and thulium laser vaporization of the prostate (ThuVap) in patients with benign prostatic hyperplasia (BPH). Materials and Methods: A retrospective analysis was conducted on 106 patients with BPH who underwent either TURP (n = 58) or ThuVap (n = 48) at our institution between April 2021 and August 2024. Preoperative and postoperative evaluations included the International Prostate Symptom Score (I-PSS), Overactive Bladder Symptom Score (OABSS), QOL index, and uroflowmetry. Perioperative outcomes, including operative time, catheterization duration, and hemoglobin (Hb) reduction, were also analyzed. Results: Both TURP and ThuVap showed sustained improvements in I-PSS, OABSS, and QOL index during the 3-month follow-up period, with no significant differences between the groups. ThuVap demonstrated a significantly lower rate of Hb reduction on the first postoperative day compared to TURP (5.9% vs. 8.5%, P Discussion: The findings indicate that both TURP and ThuVap effectively improve postoperative QOL. ThuVap's reduced bleeding may provide advantages in patients with higher cardiovascular or bleeding risks. However, variations in operative time between studies may be influenced by factors such as surgeons' experience and institutional protocols. Conclusion: Both TURP and ThuVap are effective surgical options for improving QOL in BPH patients. However, surgical efficiency and outcomes may be influenced by the surgeon's expertise and the preoperative condition of the patients. ThuVap offers additional benefits of reduced intraoperative bleeding, which may support its use in selected cases.
},
 year = {2025}
}

Copy | Download

TY - JOUR
T1 - Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)

AU - Yuki Matsui
AU - Wahei Yanagida
AU - Jun Morita
AU - Takashi Fukagai
Y1 - 2025/01/24
PY - 2025
N1 - https://doi.org/10.11648/j.ijcu.20250901.13
DO - 10.11648/j.ijcu.20250901.13
T2 - International Journal of Clinical Urology
JF - International Journal of Clinical Urology
JO - International Journal of Clinical Urology
SP - 13
EP - 19
PB - Science Publishing Group
SN - 2640-1355
UR - https://doi.org/10.11648/j.ijcu.20250901.13
AB - Objective: This study aimed to compare short-term quality of life (QOL) outcomes and perioperative parameters between transurethral resection of the prostate (TURP) and thulium laser vaporization of the prostate (ThuVap) in patients with benign prostatic hyperplasia (BPH). Materials and Methods: A retrospective analysis was conducted on 106 patients with BPH who underwent either TURP (n = 58) or ThuVap (n = 48) at our institution between April 2021 and August 2024. Preoperative and postoperative evaluations included the International Prostate Symptom Score (I-PSS), Overactive Bladder Symptom Score (OABSS), QOL index, and uroflowmetry. Perioperative outcomes, including operative time, catheterization duration, and hemoglobin (Hb) reduction, were also analyzed. Results: Both TURP and ThuVap showed sustained improvements in I-PSS, OABSS, and QOL index during the 3-month follow-up period, with no significant differences between the groups. ThuVap demonstrated a significantly lower rate of Hb reduction on the first postoperative day compared to TURP (5.9% vs. 8.5%, P Discussion: The findings indicate that both TURP and ThuVap effectively improve postoperative QOL. ThuVap's reduced bleeding may provide advantages in patients with higher cardiovascular or bleeding risks. However, variations in operative time between studies may be influenced by factors such as surgeons' experience and institutional protocols. Conclusion: Both TURP and ThuVap are effective surgical options for improving QOL in BPH patients. However, surgical efficiency and outcomes may be influenced by the surgeon's expertise and the preoperative condition of the patients. ThuVap offers additional benefits of reduced intraoperative bleeding, which may support its use in selected cases.

VL - 9
IS - 1
ER -

Copy | Download

Author Information

Yuki Matsui

Department of Urology, Showa University School of Medicine, Tokyo, Japan

Contact Email

http://orcid.org/0000-0002-1451-9837
Wahei Yanagida

Department of Urology, Hitachi Medical Center, Ibaraki, Japan

http://orcid.org/0009-0000-7492-9590
Jun Morita

Department of Urology, Showa University Fujigaoka Hospital, Kanagawa, Japan

http://orcid.org/0000-0002-4857-8683
Takashi Fukagai

Department of Urology, Showa University School of Medicine, Tokyo, Japan

http://orcid.org/0000-0003-0261-6303

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Matsui, Y., Yanagida, W., Morita, J., Fukagai, T. (2025). Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). International Journal of Clinical Urology, 9(1), 13-19. https://doi.org/10.11648/j.ijcu.20250901.13

Copy | Download

ACS Style

Matsui, Y.; Yanagida, W.; Morita, J.; Fukagai, T. Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). Int. J. Clin. Urol. 2025, 9(1), 13-19. doi: 10.11648/j.ijcu.20250901.13

Copy | Download

AMA Style

Matsui Y, Yanagida W, Morita J, Fukagai T. Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP). Int J Clin Urol. 2025;9(1):13-19. doi: 10.11648/j.ijcu.20250901.13

Copy | Download

@article{10.11648/j.ijcu.20250901.13,
  author = {Yuki Matsui and Wahei Yanagida and Jun Morita and Takashi Fukagai},
  title = {Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)
},
  journal = {International Journal of Clinical Urology},
  volume = {9},
  number = {1},
  pages = {13-19},
  doi = {10.11648/j.ijcu.20250901.13},
  url = {https://doi.org/10.11648/j.ijcu.20250901.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20250901.13},
  abstract = {Objective: This study aimed to compare short-term quality of life (QOL) outcomes and perioperative parameters between transurethral resection of the prostate (TURP) and thulium laser vaporization of the prostate (ThuVap) in patients with benign prostatic hyperplasia (BPH). Materials and Methods: A retrospective analysis was conducted on 106 patients with BPH who underwent either TURP (n = 58) or ThuVap (n = 48) at our institution between April 2021 and August 2024. Preoperative and postoperative evaluations included the International Prostate Symptom Score (I-PSS), Overactive Bladder Symptom Score (OABSS), QOL index, and uroflowmetry. Perioperative outcomes, including operative time, catheterization duration, and hemoglobin (Hb) reduction, were also analyzed. Results: Both TURP and ThuVap showed sustained improvements in I-PSS, OABSS, and QOL index during the 3-month follow-up period, with no significant differences between the groups. ThuVap demonstrated a significantly lower rate of Hb reduction on the first postoperative day compared to TURP (5.9% vs. 8.5%, P Discussion: The findings indicate that both TURP and ThuVap effectively improve postoperative QOL. ThuVap's reduced bleeding may provide advantages in patients with higher cardiovascular or bleeding risks. However, variations in operative time between studies may be influenced by factors such as surgeons' experience and institutional protocols. Conclusion: Both TURP and ThuVap are effective surgical options for improving QOL in BPH patients. However, surgical efficiency and outcomes may be influenced by the surgeon's expertise and the preoperative condition of the patients. ThuVap offers additional benefits of reduced intraoperative bleeding, which may support its use in selected cases.
},
 year = {2025}
}

Copy | Download

TY - JOUR
T1 - Short-Term Quality of Life Outcomes: A Comparative Analysis of Thulium Laser Vaporization (ThuVap) vs. Transurethral Resection of the Prostate (TURP)

VL - 9
IS - 1
ER -

Copy | Download