Exudates are substances that ooze out of the pores of diseased and/or damaged tissue in plant that are well-used in flourishing international and local uses in Burkina Faso. Previously, the ethnopharmacological investigations in Center region showed that there are lot of medicinal uses like as old wounds, skin disorders diseases treatment. The current study aims to highlight the antitumoral potential of nine resins form central region. One hundred grams of each resin were placed at -80°C before extraction. The resins were grinded, and the powder was stirred twice with 1L and 500 mL of CHCl3 respectively for 24h. The antiproliferative effect was determined by using MTT colorimetric assay with chloroformic extracts from resin of each plant and the concentrations which inhibited 50% of cell proliferation (IC50) were determinated graphically. The results showed that the IC50 of A549 proliferative inhibition was form 5.78 (Lannea microcarpa) to 32.48 µg/mL (Daniellia oliveri) and U373 inhibition IC50 was from 12.90 (L. macrocarpa) to 41.12 µg/mL (Boswellia dalzielli). The Keratinocytes IC50 was form 1.57 (L. macrocarpa) to 20.4 µg/mL (Boswellia dalzielli). Interestingly, the resin extract form L. macrocarpa resin was a best source of anticancer compounds for the A549 and U373 following by Bombax costatum resin. In the contrast Commiphora africana (Burseraceae) resin was the less antiproliferation effect. The exudates resin from plants that were a source of bioactive compounds could explain of the medicinal uses like as anti-inflammatory, wound healing, and skin ailments in Burkina Faso.
| Published in | International Journal of Pharmacy and Chemistry (Volume 8, Issue 1) |
| DOI | 10.11648/j.ijpc.20220801.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Traditional Medicine, Resins, Antiproliferative
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APA Style
Aminata Pagnimdebsom Nacoulma, Moussa Compaoré, Sahabi Bakasso, Naamwin-So-Bawfu Romaric Meda, Martin Kiendrebeogo. (2022). Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso. International Journal of Pharmacy and Chemistry, 8(1), 1-4. https://doi.org/10.11648/j.ijpc.20220801.11
ACS Style
Aminata Pagnimdebsom Nacoulma; Moussa Compaoré; Sahabi Bakasso; Naamwin-So-Bawfu Romaric Meda; Martin Kiendrebeogo. Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso. Int. J. Pharm. Chem. 2022, 8(1), 1-4. doi: 10.11648/j.ijpc.20220801.11
AMA Style
Aminata Pagnimdebsom Nacoulma, Moussa Compaoré, Sahabi Bakasso, Naamwin-So-Bawfu Romaric Meda, Martin Kiendrebeogo. Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso. Int J Pharm Chem. 2022;8(1):1-4. doi: 10.11648/j.ijpc.20220801.11
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author = {Aminata Pagnimdebsom Nacoulma and Moussa Compaoré and Sahabi Bakasso and Naamwin-So-Bawfu Romaric Meda and Martin Kiendrebeogo},
title = {Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso},
journal = {International Journal of Pharmacy and Chemistry},
volume = {8},
number = {1},
pages = {1-4},
doi = {10.11648/j.ijpc.20220801.11},
url = {https://doi.org/10.11648/j.ijpc.20220801.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20220801.11},
abstract = {Exudates are substances that ooze out of the pores of diseased and/or damaged tissue in plant that are well-used in flourishing international and local uses in Burkina Faso. Previously, the ethnopharmacological investigations in Center region showed that there are lot of medicinal uses like as old wounds, skin disorders diseases treatment. The current study aims to highlight the antitumoral potential of nine resins form central region. One hundred grams of each resin were placed at -80°C before extraction. The resins were grinded, and the powder was stirred twice with 1L and 500 mL of CHCl3 respectively for 24h. The antiproliferative effect was determined by using MTT colorimetric assay with chloroformic extracts from resin of each plant and the concentrations which inhibited 50% of cell proliferation (IC50) were determinated graphically. The results showed that the IC50 of A549 proliferative inhibition was form 5.78 (Lannea microcarpa) to 32.48 µg/mL (Daniellia oliveri) and U373 inhibition IC50 was from 12.90 (L. macrocarpa) to 41.12 µg/mL (Boswellia dalzielli). The Keratinocytes IC50 was form 1.57 (L. macrocarpa) to 20.4 µg/mL (Boswellia dalzielli). Interestingly, the resin extract form L. macrocarpa resin was a best source of anticancer compounds for the A549 and U373 following by Bombax costatum resin. In the contrast Commiphora africana (Burseraceae) resin was the less antiproliferation effect. The exudates resin from plants that were a source of bioactive compounds could explain of the medicinal uses like as anti-inflammatory, wound healing, and skin ailments in Burkina Faso.},
year = {2022}
}
TY - JOUR T1 - Anti-proliferative Effect of Nine Resins from Medicinal Plants of Burkina Faso AU - Aminata Pagnimdebsom Nacoulma AU - Moussa Compaoré AU - Sahabi Bakasso AU - Naamwin-So-Bawfu Romaric Meda AU - Martin Kiendrebeogo Y1 - 2022/01/08 PY - 2022 N1 - https://doi.org/10.11648/j.ijpc.20220801.11 DO - 10.11648/j.ijpc.20220801.11 T2 - International Journal of Pharmacy and Chemistry JF - International Journal of Pharmacy and Chemistry JO - International Journal of Pharmacy and Chemistry SP - 1 EP - 4 PB - Science Publishing Group SN - 2575-5749 UR - https://doi.org/10.11648/j.ijpc.20220801.11 AB - Exudates are substances that ooze out of the pores of diseased and/or damaged tissue in plant that are well-used in flourishing international and local uses in Burkina Faso. Previously, the ethnopharmacological investigations in Center region showed that there are lot of medicinal uses like as old wounds, skin disorders diseases treatment. The current study aims to highlight the antitumoral potential of nine resins form central region. One hundred grams of each resin were placed at -80°C before extraction. The resins were grinded, and the powder was stirred twice with 1L and 500 mL of CHCl3 respectively for 24h. The antiproliferative effect was determined by using MTT colorimetric assay with chloroformic extracts from resin of each plant and the concentrations which inhibited 50% of cell proliferation (IC50) were determinated graphically. The results showed that the IC50 of A549 proliferative inhibition was form 5.78 (Lannea microcarpa) to 32.48 µg/mL (Daniellia oliveri) and U373 inhibition IC50 was from 12.90 (L. macrocarpa) to 41.12 µg/mL (Boswellia dalzielli). The Keratinocytes IC50 was form 1.57 (L. macrocarpa) to 20.4 µg/mL (Boswellia dalzielli). Interestingly, the resin extract form L. macrocarpa resin was a best source of anticancer compounds for the A549 and U373 following by Bombax costatum resin. In the contrast Commiphora africana (Burseraceae) resin was the less antiproliferation effect. The exudates resin from plants that were a source of bioactive compounds could explain of the medicinal uses like as anti-inflammatory, wound healing, and skin ailments in Burkina Faso. VL - 8 IS - 1 ER -
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