CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of <i>Acacia Nilotica</i>

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran

doi:doi:10.11648/j.pst.20170102.11

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CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran

Published in Pharmaceutical Science and Technology (Volume 1, Issue 2)

Received: 16 June 2017 Accepted: 5 July 2017 Published: 16 August 2017

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Abstract

According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.

Published in	Pharmaceutical Science and Technology (Volume 1, Issue 2)
DOI	10.11648/j.pst.20170102.11
Page(s)	13-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Acacia Nilotica, CNS-Antidepressant Activity, Stem Bark and Methanolic Extract

References

[1]	Drag G, Vifen T. Mental health: new understanding new hope. J world health rpt., 2001; 14: 203-211.
[2]	Reynolds EH. Brain and mind: achallange for WHO. Lancet 2003; 361: 1924-1925.
[3]	Thase ME, Howland RH. Biological process in depression: an update and integration. Handbook of depression. New York.
[4]	(a) Coates Palgrave, K. 1990. Trees of southern Africa. Struik, Cape Town. Davidson, L. 1981. Acacias, a field guide to the identification of the species of southern Africa. Centaur Publishers, Johannesburg.
[5]	Lewis, G., B. Schrire, B. Mac Kinder, and M. Lock (eds). 2005. Legumes of the world. Royal Botanical Gardens, Kew, UK.
[6]	Rundel, P. W. 1989. Ecological success in relation to plant form and function in the woody legumes. In C. H. Stirton and J. L. Zarucchi (eds.). Advances in legume biology, Monographs in Systematic Botany from the Missouri Botanical Gardens 29: 377-398.
[7]	McKey, D. 1994. Legumes and nitrogen: the evolutionary ecology of a nitrogen-demanding lifestyle. Pages 211–228 in Advances in Legume Systematics, part 5, the nitrogen factor (J. I. Sprent and D. McKey, eds.). Royal Botanic Gardens, Kew, UK.
[8]	Polhill, R. M. 1994. Classification of the Leguminosae. Pages xxxv–xlviii in Phytochemical Dictionary of the Leguminosae (F. A. Bisby, J. Buckingham, and J. B. Harborne, eds.). Chapman and Hall, New York, NY.
[9]	Polhill, R. M., and P. H. Raven (eds.). 1981. Advances in legume systematics, parts 1 and 2. Royal Botanic Gardens, Kew, UK.
[10]	Graham, P. H., and C. P. Vance. 2003. Legumes: importance and constraints to greater use. Plant Physiol. 131: 872 – 877.
[11]	Gepts, P., W. D. Beavis, E. C. Brummer, R. C. Shoemaker, H. T. Stalker, N. F. Weeden, and N. D. Young. 2005. Legumes as a model plant family. Genomics for food and feed report of the cross-legume advances through genomics conference. Plant Physiology 137: 1228–1235.
[12]	Mann A, Gbate M, Umar A., 2003. Medicinal and Economic plants. Jube Evans Books and Publication, Bida, Nigeria. p. 160.
[13]	Bargal Kiran, Bargali S. S. (2009). Acacia nilotica: a multipurpose leguminous plant. Nature and Science, 7(4): 11-19. 9.
[14]	Bennison J. J. Paterson R. T. (1994). The use of Trees by Livestock Acacia Production Programme. 1: 160-164. 10.
[15]	The Ayurvedic pharmacopoeia of India, government of India Ministry of health and family welfare, Department of Ayush. I (I): 29.
[16]	Kalaivani T, Rajasekaran C, Suthindhiran K, Mathew L (2010b). Free radical scavenging, cytotoxic and hemolytic activities from leaves of Acacia nilotica (l.) wild. ex. delile subsp. indica (benth.) brenan. Evid. Based Complement. Alternat. Med., 2011: 274741.
[17]	Baravkar AA, Kale RN, Patil RN, Sawant SD (2008). Pharmaceutical and biological evaluation of formulated cream of methanolic extract of Acacia nilotica leaves. Res. J. Pharm. Technol., 1(4): 481-483.
[18]	Agrawal S, Kulkarni GT, Sharma VN (2010). A comparative study on the antioxidant activity of methanol extracts of acacia. Adv. Nat. Appl. Sci., 4(1): 78-84.
[19]	El-Tahir A, Satti GM, Khalid SA (1999). Antiplasmodial activity of selected sudanese medicinal plants with emphasis on Acacia nilotica. Phytother. Res., 13: 474-478.
[20]	Gilani AH, Shaheen F, Zaman M, Janbaz KH, Shah BH, Akhtar MS (1999). Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods. Phytother. Res., 13: 665-669.
[21]	Cox, M. L. 1997. Homichloda barker (Jacoby) (Coleoptera: Chrysomelidae: Alticinae) a Weed Risk Assessment Version 5- Draft June 2, 2009 page 16 candidate agent for the biocontrol of prickly acacia, Acacia nilotica (Mimosaceae) in Australia. Journal of Natural History 31: 935-964.
[22]	Yu ZF. Kong LD and Chen. Antidepressant activity of aqueous extract of Curcuma longa in mice. J Ethnopharmacon. 2002; 83: 161.

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APA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. (2017). CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharmaceutical Science and Technology, 1(2), 13-19. https://doi.org/10.11648/j.pst.20170102.11

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ACS Style

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm. Sci. Technol. 2017, 1(2), 13-19. doi: 10.11648/j.pst.20170102.11

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AMA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm Sci Technol. 2017;1(2):13-19. doi: 10.11648/j.pst.20170102.11

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@article{10.11648/j.pst.20170102.11,
  author = {Md. Mamun-Or-Rashid and Muhammad Ashiqul Islam and Taniya Idris and Md. Shah Amran},
  title = {CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica},
  journal = {Pharmaceutical Science and Technology},
  volume = {1},
  number = {2},
  pages = {13-19},
  doi = {10.11648/j.pst.20170102.11},
  url = {https://doi.org/10.11648/j.pst.20170102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20170102.11},
  abstract = {According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.},
 year = {2017}
}

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TY  - JOUR
T1  - CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
AU  - Md. Mamun-Or-Rashid
AU  - Muhammad Ashiqul Islam
AU  - Taniya Idris
AU  - Md. Shah Amran
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DO  - 10.11648/j.pst.20170102.11
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
SP  - 13
EP  - 19
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20170102.11
AB  - According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
VL  - 1
IS  - 2
ER  -

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Author Information

Md. Mamun-Or-Rashid

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Muhammad Ashiqul Islam

Department of Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Taniya Idris

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh
Md. Shah Amran

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh

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APA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. (2017). CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharmaceutical Science and Technology, 1(2), 13-19. https://doi.org/10.11648/j.pst.20170102.11

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ACS Style

Md. Mamun-Or-Rashid; Muhammad Ashiqul Islam; Taniya Idris; Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm. Sci. Technol. 2017, 1(2), 13-19. doi: 10.11648/j.pst.20170102.11

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AMA Style

Md. Mamun-Or-Rashid, Muhammad Ashiqul Islam, Taniya Idris, Md. Shah Amran. CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica. Pharm Sci Technol. 2017;1(2):13-19. doi: 10.11648/j.pst.20170102.11

Copy | Download

@article{10.11648/j.pst.20170102.11,
  author = {Md. Mamun-Or-Rashid and Muhammad Ashiqul Islam and Taniya Idris and Md. Shah Amran},
  title = {CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica},
  journal = {Pharmaceutical Science and Technology},
  volume = {1},
  number = {2},
  pages = {13-19},
  doi = {10.11648/j.pst.20170102.11},
  url = {https://doi.org/10.11648/j.pst.20170102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20170102.11},
  abstract = {According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
AU  - Md. Mamun-Or-Rashid
AU  - Muhammad Ashiqul Islam
AU  - Taniya Idris
AU  - Md. Shah Amran
Y1  - 2017/08/16
PY  - 2017
N1  - https://doi.org/10.11648/j.pst.20170102.11
DO  - 10.11648/j.pst.20170102.11
T2  - Pharmaceutical Science and Technology
JF  - Pharmaceutical Science and Technology
JO  - Pharmaceutical Science and Technology
SP  - 13
EP  - 19
PB  - Science Publishing Group
SN  - 2640-4540
UR  - https://doi.org/10.11648/j.pst.20170102.11
AB  - According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
VL  - 1
IS  - 2
ER  -

Copy | Download