Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics has dropped dramatically day by day. Metal complex [Co (SB) (SCN)] (where, SB = 2-[(6-Amino-hexylimino)-methyl] phenol) have been reported for the purpose of searching new antimicrobial agents. The Schiff base and it’s transition metal complex was characterized by means of several physiochemical and spectroscopic methods. Several biomedical toxicological properties of the complex has been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophages, alkaline phosphatase activity, haematological effect and biopsy of tumour. The synthesized Schiff base Co (II) complex was found to have anticancer and cytotoxic function.
| Published in | Biochemistry and Molecular Biology (Volume 4, Issue 3) |
| DOI | 10.11648/j.bmb.20190403.11 |
| Page(s) | 35-41 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Transition Metal Complex, Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Studies
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APA Style
Kudrat-E-Zahan, Saddam Hossain, M. M. Haque, Laila Arjuman Banu, M. A. Matin, et al. (2019). Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex. Biochemistry and Molecular Biology, 4(3), 35-41. https://doi.org/10.11648/j.bmb.20190403.11
ACS Style
Kudrat-E-Zahan; Saddam Hossain; M. M. Haque; Laila Arjuman Banu; M. A. Matin, et al. Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex. Biochem. Mol. Biol. 2019, 4(3), 35-41. doi: 10.11648/j.bmb.20190403.11
AMA Style
Kudrat-E-Zahan, Saddam Hossain, M. M. Haque, Laila Arjuman Banu, M. A. Matin, et al. Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex. Biochem Mol Biol. 2019;4(3):35-41. doi: 10.11648/j.bmb.20190403.11
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Download@article{10.11648/j.bmb.20190403.11,
author = {Kudrat-E-Zahan and Saddam Hossain and M. M. Haque and Laila Arjuman Banu and M. A. Matin and Nur Amin Bitu and Ahsan Habib and Ashrafuzzaman and Nayon Uddin and M. S. Islam},
title = {Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex},
journal = {Biochemistry and Molecular Biology},
volume = {4},
number = {3},
pages = {35-41},
doi = {10.11648/j.bmb.20190403.11},
url = {https://doi.org/10.11648/j.bmb.20190403.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20190403.11},
abstract = {Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics has dropped dramatically day by day. Metal complex [Co (SB) (SCN)] (where, SB = 2-[(6-Amino-hexylimino)-methyl] phenol) have been reported for the purpose of searching new antimicrobial agents. The Schiff base and it’s transition metal complex was characterized by means of several physiochemical and spectroscopic methods. Several biomedical toxicological properties of the complex has been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophages, alkaline phosphatase activity, haematological effect and biopsy of tumour. The synthesized Schiff base Co (II) complex was found to have anticancer and cytotoxic function.},
year = {2019}
}
TY - JOUR T1 - Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial Investigation on Synthesized Schiff Base Co(II) Ion Complex AU - Kudrat-E-Zahan AU - Saddam Hossain AU - M. M. Haque AU - Laila Arjuman Banu AU - M. A. Matin AU - Nur Amin Bitu AU - Ahsan Habib AU - Ashrafuzzaman AU - Nayon Uddin AU - M. S. Islam Y1 - 2019/08/06 PY - 2019 N1 - https://doi.org/10.11648/j.bmb.20190403.11 DO - 10.11648/j.bmb.20190403.11 T2 - Biochemistry and Molecular Biology JF - Biochemistry and Molecular Biology JO - Biochemistry and Molecular Biology SP - 35 EP - 41 PB - Science Publishing Group SN - 2575-5048 UR - https://doi.org/10.11648/j.bmb.20190403.11 AB - Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics has dropped dramatically day by day. Metal complex [Co (SB) (SCN)] (where, SB = 2-[(6-Amino-hexylimino)-methyl] phenol) have been reported for the purpose of searching new antimicrobial agents. The Schiff base and it’s transition metal complex was characterized by means of several physiochemical and spectroscopic methods. Several biomedical toxicological properties of the complex has been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophages, alkaline phosphatase activity, haematological effect and biopsy of tumour. The synthesized Schiff base Co (II) complex was found to have anticancer and cytotoxic function. VL - 4 IS - 3 ER -
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