Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention

Mohammed Ismail Ali; Wala Farid Abd El-Aziz; Adel Imam Abd El-Magid; Neveen Ibrahim Samy

doi:doi:10.11648/j.ccr.20180203.15

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Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention

Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy

Published in Cardiology and Cardiovascular Research (Volume 2, Issue 3)

Received: 28 August 2018 Accepted: 15 October 2018 Published: 5 November 2018

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Abstract

Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.

Published in	Cardiology and Cardiovascular Research (Volume 2, Issue 3)
DOI	10.11648/j.ccr.20180203.15
Page(s)	68-74
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Acute Myocardial Infarction, Primary Percutaneous Coronary Intervention, No-Reflow, Coronary Thrombosis

References

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APA Style

Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. (2018). Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiology and Cardiovascular Research, 2(3), 68-74. https://doi.org/10.11648/j.ccr.20180203.15

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ACS Style

Mohammed Ismail Ali; Wala Farid Abd El-Aziz; Adel Imam Abd El-Magid; Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol. Cardiovasc. Res. 2018, 2(3), 68-74. doi: 10.11648/j.ccr.20180203.15

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AMA Style

Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol Cardiovasc Res. 2018;2(3):68-74. doi: 10.11648/j.ccr.20180203.15

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@article{10.11648/j.ccr.20180203.15,
  author = {Mohammed Ismail Ali and Wala Farid Abd El-Aziz and Adel Imam Abd El-Magid and Neveen Ibrahim Samy},
  title = {Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention},
  journal = {Cardiology and Cardiovascular Research},
  volume = {2},
  number = {3},
  pages = {68-74},
  doi = {10.11648/j.ccr.20180203.15},
  url = {https://doi.org/10.11648/j.ccr.20180203.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180203.15},
  abstract = {Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.},
 year = {2018}
}

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TY  - JOUR
T1  - Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention
AU  - Mohammed Ismail Ali
AU  - Wala Farid Abd El-Aziz
AU  - Adel Imam Abd El-Magid
AU  - Neveen Ibrahim Samy
Y1  - 2018/11/05
PY  - 2018
N1  - https://doi.org/10.11648/j.ccr.20180203.15
DO  - 10.11648/j.ccr.20180203.15
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 68
EP  - 74
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20180203.15
AB  - Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.
VL  - 2
IS  - 3
ER  -

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Author Information

Mohammed Ismail Ali

Cardiology Department, 6 October Hospital, General Health Insurance, Giza, Egypt
Wala Farid Abd El-Aziz

Cardiology Department, Menoufia University, Menoufia, Egypt
Adel Imam Abd El-Magid

Cardiology Department, National Heart Institute, Giza, Egypt
Neveen Ibrahim Samy

Cardiology Department, Menoufia University, Menoufia, Egypt

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APA Style

Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. (2018). Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiology and Cardiovascular Research, 2(3), 68-74. https://doi.org/10.11648/j.ccr.20180203.15

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ACS Style

Mohammed Ismail Ali; Wala Farid Abd El-Aziz; Adel Imam Abd El-Magid; Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol. Cardiovasc. Res. 2018, 2(3), 68-74. doi: 10.11648/j.ccr.20180203.15

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AMA Style

Mohammed Ismail Ali, Wala Farid Abd El-Aziz, Adel Imam Abd El-Magid, Neveen Ibrahim Samy. Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention. Cardiol Cardiovasc Res. 2018;2(3):68-74. doi: 10.11648/j.ccr.20180203.15

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@article{10.11648/j.ccr.20180203.15,
  author = {Mohammed Ismail Ali and Wala Farid Abd El-Aziz and Adel Imam Abd El-Magid and Neveen Ibrahim Samy},
  title = {Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention},
  journal = {Cardiology and Cardiovascular Research},
  volume = {2},
  number = {3},
  pages = {68-74},
  doi = {10.11648/j.ccr.20180203.15},
  url = {https://doi.org/10.11648/j.ccr.20180203.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180203.15},
  abstract = {Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.},
 year = {2018}
}

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TY  - JOUR
T1  - Predictors of no-Reflow in Patients with ST-Segment Elevation Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention
AU  - Mohammed Ismail Ali
AU  - Wala Farid Abd El-Aziz
AU  - Adel Imam Abd El-Magid
AU  - Neveen Ibrahim Samy
Y1  - 2018/11/05
PY  - 2018
N1  - https://doi.org/10.11648/j.ccr.20180203.15
DO  - 10.11648/j.ccr.20180203.15
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 68
EP  - 74
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20180203.15
AB  - Background: Primary percutaneous coronary intervention (PCI) is the preferred method of ST-segment elevation acute myocardial infarction (STEMI) management but no-reflow phenomenon is one of its major complications that affects patient's outcome. Objective: Identification of possible clinical, angiographic and procedural predictors for no-reflow in patients with AMI after primary percutaneous coronary intervention (PCI). Methods: A total of hundred patients with AMI who had been treated by primary PCI at the National heart institute (NHI) and cardiology department, Menoufia University hospital were enrolled in this study, according to thrombolysis in myocardial infarction (TIMI) flow grade, patients were divided into a reflow group (TIMI 3) and a no-reflow group (TIMI ≤ 2). The clinical, angiographic and procedural data were compared between both groups. Discussion: Sixteen patients (16%) developed no-reflow phenomenon after primary PCI. Statistical analysis showed that time from onset to reperfusion, low initial TIMI flow grade, high thrombus burden, long lesion length and large reference luminal diameter were correlated with no-reflow (P < 0.05 for all) and were considered to be independent predictors of no-reflow. Conclusion: The occurrence of no-reflow after primary PCI for acute myocardial infarction can be predicted by certain clinical, angiographic and procedural features.
VL  - 2
IS  - 3
ER  -

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