Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study

Reham Mostafa Elgammal; Mona Adel Elsaiedy; Mahmoud Zki Alamrosy; Mohamed Elsaied Elsetiha; Magdy Mohamed Almasry

doi:doi:10.11648/j.ccr.20230702.14

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Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study

Reham Mostafa Elgammal, Mona Adel Elsaiedy, Mahmoud Zki Alamrosy, Mohamed Elsaied Elsetiha, Magdy Mohamed Almasry

Published in Cardiology and Cardiovascular Research (Volume 7, Issue 2)

Received: 18 February 2023 Accepted: 4 March 2023 Published: 31 May 2023

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Abstract

Background: Mitral valve regurgitation (MR) is a major cause of morbidity and death across the world. It obliges volume overload over left ventricle (LV) leading to LV dysfunction and subsequently heart failure. Detection of deleterious effect on left ventricle is crucial in guiding surgical decision in such cases. Aim of the study: Comprehensive assessment of left ventricle in case of significant primary mitral incompetence using multimodality imaging tools, namely 2D echo, 3D echo and cardiac magnetic resonance (CMR). Methods: 40 consecutive patients have been recruited from May 2019 to May 2021 in a prospective observational study which has been conducted in Aswan and Tanta heart centers. All patients suffered from significant primary MR. Patients underwent 2D echo where LV volumes, function and global longitudinal strain (GLS) were calculated. The same parameters were calculated by 3D echo. CMR study for all patient was done and post processing was done on appropriate software. LV volumes, function and GLS (feature tracking) were calculated in addition to detection of myocardial fibrosis. Results: End diastolic volume (EDV) and end systolic volume (ESV) were significantly larger when measured by CMR (mean EDV = 220.63, mean ESV = 87.6) as compared to 3D echo (mean EDV =180.43, mean ESV =68.13) and 2D echo (mean EDV =166.25, mean ESV=61.58) (all P <0.001). EDV measures were strongly correlated with CMR and 3D echocardiography (r=0.88, p < 0.001).2D echo ESV measures were strongly correlated with CMR and 3D echo (r=0.7 and 0.63 respectively, P<0.001).3D echo ESV measures were moderately correlated with CMR (r=0.5, P<0.001). GLS values measured by 2D and CMR were moderately correlated (r=0.5, p<0.001). Conclusion: Left ventricle is playing an important role in the prognosis and intervention decision in mitral regurgitation. It’s important to identify early deleterious LV changes so that intervention is recommended prior to the development of irreversible LV damage.

Published in	Cardiology and Cardiovascular Research (Volume 7, Issue 2)
DOI	10.11648/j.ccr.20230702.14
Page(s)	38-49
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Primary Mitral Regurgitation, MR, CMR, 2D Echo, 3D Echo, GLS, Left Ventricle

References

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APA Style

Reham Mostafa Elgammal, Mona Adel Elsaiedy, Mahmoud Zki Alamrosy, Mohamed Elsaied Elsetiha, Magdy Mohamed Almasry. (2023). Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiology and Cardiovascular Research, 7(2), 38-49. https://doi.org/10.11648/j.ccr.20230702.14

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ACS Style

Reham Mostafa Elgammal; Mona Adel Elsaiedy; Mahmoud Zki Alamrosy; Mohamed Elsaied Elsetiha; Magdy Mohamed Almasry. Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiol. Cardiovasc. Res. 2023, 7(2), 38-49. doi: 10.11648/j.ccr.20230702.14

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AMA Style

Reham Mostafa Elgammal, Mona Adel Elsaiedy, Mahmoud Zki Alamrosy, Mohamed Elsaied Elsetiha, Magdy Mohamed Almasry. Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiol Cardiovasc Res. 2023;7(2):38-49. doi: 10.11648/j.ccr.20230702.14

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@article{10.11648/j.ccr.20230702.14,
  author = {Reham Mostafa Elgammal and Mona Adel Elsaiedy and Mahmoud Zki Alamrosy and Mohamed Elsaied Elsetiha and Magdy Mohamed Almasry},
  title = {Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study},
  journal = {Cardiology and Cardiovascular Research},
  volume = {7},
  number = {2},
  pages = {38-49},
  doi = {10.11648/j.ccr.20230702.14},
  url = {https://doi.org/10.11648/j.ccr.20230702.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20230702.14},
  abstract = {Background: Mitral valve regurgitation (MR) is a major cause of morbidity and death across the world. It obliges volume overload over left ventricle (LV) leading to LV dysfunction and subsequently heart failure. Detection of deleterious effect on left ventricle is crucial in guiding surgical decision in such cases. Aim of the study: Comprehensive assessment of left ventricle in case of significant primary mitral incompetence using multimodality imaging tools, namely 2D echo, 3D echo and cardiac magnetic resonance (CMR). Methods: 40 consecutive patients have been recruited from May 2019 to May 2021 in a prospective observational study which has been conducted in Aswan and Tanta heart centers. All patients suffered from significant primary MR. Patients underwent 2D echo where LV volumes, function and global longitudinal strain (GLS) were calculated. The same parameters were calculated by 3D echo. CMR study for all patient was done and post processing was done on appropriate software. LV volumes, function and GLS (feature tracking) were calculated in addition to detection of myocardial fibrosis. Results: End diastolic volume (EDV) and end systolic volume (ESV) were significantly larger when measured by CMR (mean EDV = 220.63, mean ESV = 87.6) as compared to 3D echo (mean EDV =180.43, mean ESV =68.13) and 2D echo (mean EDV =166.25, mean ESV=61.58) (all P  Conclusion: Left ventricle is playing an important role in the prognosis and intervention decision in mitral regurgitation. It’s important to identify early deleterious LV changes so that intervention is recommended prior to the development of irreversible LV damage.},
 year = {2023}
}

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TY  - JOUR
T1  - Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study
AU  - Reham Mostafa Elgammal
AU  - Mona Adel Elsaiedy
AU  - Mahmoud Zki Alamrosy
AU  - Mohamed Elsaied Elsetiha
AU  - Magdy Mohamed Almasry
Y1  - 2023/05/31
PY  - 2023
N1  - https://doi.org/10.11648/j.ccr.20230702.14
DO  - 10.11648/j.ccr.20230702.14
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 38
EP  - 49
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20230702.14
AB  - Background: Mitral valve regurgitation (MR) is a major cause of morbidity and death across the world. It obliges volume overload over left ventricle (LV) leading to LV dysfunction and subsequently heart failure. Detection of deleterious effect on left ventricle is crucial in guiding surgical decision in such cases. Aim of the study: Comprehensive assessment of left ventricle in case of significant primary mitral incompetence using multimodality imaging tools, namely 2D echo, 3D echo and cardiac magnetic resonance (CMR). Methods: 40 consecutive patients have been recruited from May 2019 to May 2021 in a prospective observational study which has been conducted in Aswan and Tanta heart centers. All patients suffered from significant primary MR. Patients underwent 2D echo where LV volumes, function and global longitudinal strain (GLS) were calculated. The same parameters were calculated by 3D echo. CMR study for all patient was done and post processing was done on appropriate software. LV volumes, function and GLS (feature tracking) were calculated in addition to detection of myocardial fibrosis. Results: End diastolic volume (EDV) and end systolic volume (ESV) were significantly larger when measured by CMR (mean EDV = 220.63, mean ESV = 87.6) as compared to 3D echo (mean EDV =180.43, mean ESV =68.13) and 2D echo (mean EDV =166.25, mean ESV=61.58) (all P  Conclusion: Left ventricle is playing an important role in the prognosis and intervention decision in mitral regurgitation. It’s important to identify early deleterious LV changes so that intervention is recommended prior to the development of irreversible LV damage.
VL  - 7
IS  - 2
ER  -

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Author Information

Reham Mostafa Elgammal

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
Mona Adel Elsaiedy

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
Mahmoud Zki Alamrosy

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
Mohamed Elsaied Elsetiha

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
Magdy Mohamed Almasry

Department of Cardiovascular Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

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APA Style

Reham Mostafa Elgammal, Mona Adel Elsaiedy, Mahmoud Zki Alamrosy, Mohamed Elsaied Elsetiha, Magdy Mohamed Almasry. (2023). Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiology and Cardiovascular Research, 7(2), 38-49. https://doi.org/10.11648/j.ccr.20230702.14

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ACS Style

Reham Mostafa Elgammal; Mona Adel Elsaiedy; Mahmoud Zki Alamrosy; Mohamed Elsaied Elsetiha; Magdy Mohamed Almasry. Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiol. Cardiovasc. Res. 2023, 7(2), 38-49. doi: 10.11648/j.ccr.20230702.14

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AMA Style

Reham Mostafa Elgammal, Mona Adel Elsaiedy, Mahmoud Zki Alamrosy, Mohamed Elsaied Elsetiha, Magdy Mohamed Almasry. Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study. Cardiol Cardiovasc Res. 2023;7(2):38-49. doi: 10.11648/j.ccr.20230702.14

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@article{10.11648/j.ccr.20230702.14,
  author = {Reham Mostafa Elgammal and Mona Adel Elsaiedy and Mahmoud Zki Alamrosy and Mohamed Elsaied Elsetiha and Magdy Mohamed Almasry},
  title = {Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study},
  journal = {Cardiology and Cardiovascular Research},
  volume = {7},
  number = {2},
  pages = {38-49},
  doi = {10.11648/j.ccr.20230702.14},
  url = {https://doi.org/10.11648/j.ccr.20230702.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20230702.14},
  abstract = {Background: Mitral valve regurgitation (MR) is a major cause of morbidity and death across the world. It obliges volume overload over left ventricle (LV) leading to LV dysfunction and subsequently heart failure. Detection of deleterious effect on left ventricle is crucial in guiding surgical decision in such cases. Aim of the study: Comprehensive assessment of left ventricle in case of significant primary mitral incompetence using multimodality imaging tools, namely 2D echo, 3D echo and cardiac magnetic resonance (CMR). Methods: 40 consecutive patients have been recruited from May 2019 to May 2021 in a prospective observational study which has been conducted in Aswan and Tanta heart centers. All patients suffered from significant primary MR. Patients underwent 2D echo where LV volumes, function and global longitudinal strain (GLS) were calculated. The same parameters were calculated by 3D echo. CMR study for all patient was done and post processing was done on appropriate software. LV volumes, function and GLS (feature tracking) were calculated in addition to detection of myocardial fibrosis. Results: End diastolic volume (EDV) and end systolic volume (ESV) were significantly larger when measured by CMR (mean EDV = 220.63, mean ESV = 87.6) as compared to 3D echo (mean EDV =180.43, mean ESV =68.13) and 2D echo (mean EDV =166.25, mean ESV=61.58) (all P  Conclusion: Left ventricle is playing an important role in the prognosis and intervention decision in mitral regurgitation. It’s important to identify early deleterious LV changes so that intervention is recommended prior to the development of irreversible LV damage.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Left Ventricular Assessment in Patients with Significant Mitral Incompetence; a Multi-Modality Imaging Study
AU  - Reham Mostafa Elgammal
AU  - Mona Adel Elsaiedy
AU  - Mahmoud Zki Alamrosy
AU  - Mohamed Elsaied Elsetiha
AU  - Magdy Mohamed Almasry
Y1  - 2023/05/31
PY  - 2023
N1  - https://doi.org/10.11648/j.ccr.20230702.14
DO  - 10.11648/j.ccr.20230702.14
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 38
EP  - 49
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20230702.14
AB  - Background: Mitral valve regurgitation (MR) is a major cause of morbidity and death across the world. It obliges volume overload over left ventricle (LV) leading to LV dysfunction and subsequently heart failure. Detection of deleterious effect on left ventricle is crucial in guiding surgical decision in such cases. Aim of the study: Comprehensive assessment of left ventricle in case of significant primary mitral incompetence using multimodality imaging tools, namely 2D echo, 3D echo and cardiac magnetic resonance (CMR). Methods: 40 consecutive patients have been recruited from May 2019 to May 2021 in a prospective observational study which has been conducted in Aswan and Tanta heart centers. All patients suffered from significant primary MR. Patients underwent 2D echo where LV volumes, function and global longitudinal strain (GLS) were calculated. The same parameters were calculated by 3D echo. CMR study for all patient was done and post processing was done on appropriate software. LV volumes, function and GLS (feature tracking) were calculated in addition to detection of myocardial fibrosis. Results: End diastolic volume (EDV) and end systolic volume (ESV) were significantly larger when measured by CMR (mean EDV = 220.63, mean ESV = 87.6) as compared to 3D echo (mean EDV =180.43, mean ESV =68.13) and 2D echo (mean EDV =166.25, mean ESV=61.58) (all P  Conclusion: Left ventricle is playing an important role in the prognosis and intervention decision in mitral regurgitation. It’s important to identify early deleterious LV changes so that intervention is recommended prior to the development of irreversible LV damage.
VL  - 7
IS  - 2
ER  -

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