Objective: To explore the risk factors for perioperative blood transfusion in patients with sacral tumors and provide a basis for clinical blood management. Methods: The clinical data of 69 patients with sacral tumors undergoing surgery were retrospectively analyzed. The patients were divided into the transfusion group (n=46) and the non-transfusion group (n=23) based on whether they received allogeneic red blood cell transfusion during the perioperative period. Univariate analysis was used to screen the risk factors, and variables with P<0.05 were included in the multivariate Logistic regression analysis. Results: Univariate analysis showed that there were statistically significant differences in fibrinogen (FIB), operation duration, and intraoperative blood loss between the two groups (P<0.05), while there were no statistically significant differences in gender, age, hemoglobin, red blood cell count, hematocrit, prothrombin time, activated partial thromboplastin time, alanine aminotransferase, tumor type, surgical site, and surgical position between the two groups (P>0.05). Multivariate Logistic regression analysis showed that operation duration (OR=1.63, P=0.04) and intraoperative blood loss (OR=0.06, P=0.02) were independent risk factors for perioperative blood transfusion. Among the transfusion patients, 2-4 units of suspended red blood cells accounted for 33.33%, more than 12 units accounted for 14.29%, and more than 1600mL of plasma accounted for 10.20%. Conclusion: The perioperative blood transfusion rate of patients with sacral tumors is relatively high (66.7%). The prolongation of operation time and the increase of intraoperative blood loss are independent risk factors for perioperative blood transfusion. In clinical practice, attention should be focused on high-risk patients with long operation time and large intraoperative blood loss. Preoperative blood type identification and screening for irregular antibodies should be completed, and sufficient blood reserves (8 units of red blood cells recommended) should be prepared. The transfusion department should establish a close communication and collaboration mechanism with the clinical department to ensure the supply of blood in case of sudden large blood demand, to reduce the need for allogeneic blood transfusion, reduce transfusion-related complications, and improve patient prognosis.
| Published in | Science Research (Volume 14, Issue 5) |
| DOI | 10.11648/j.sr.20261405.16 |
| Page(s) | 308-313 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2026. Published by Science Publishing Group |
Sacral Tumor Surgery, Perioperative Blood Management, Influencing Factors of Blood Transfusion
未输血组（n=23） | 输血组（n=46） | F | P | |
|---|---|---|---|---|
年龄（岁） | 43.65±19.40 | 44.87±18.93 | 0.023 | 0.879 |
RBC (g/L) | 4.72±0.56 | 4.57±0.76 | 1.573 | 0.214 |
Hct (%) | 40.6783±5.40 | 40.10±6.25 | 0.520 | 0.473 |
Hb (g/L) | 136.7±20.46 | 134.07±23.34 | 0.685 | 0.411 |
PT (s) | 12.80±1.02 | 12.84±1.20 | 0.014 | 0.907 |
APTT (s) | 32.72±4.40 | 34.38±5.27 | 0.551 | 0.461 |
FIB (mg/dL) | 291.93±56.40 | 324.16±110.66 | 6.065 | 0.016 |
ALT (U/L) | 21.87±19.57 | 22.43±12.17 | 0.300 | 0.586 |
未输血组（n=23） | 输血组（n=46） | 检验值(X²/t) | P值 | ||
|---|---|---|---|---|---|
性别 | 男 | 13 | 22 | 0.464 | 0.611 |
女 | 10 | 24 | |||
手术位置 | 骶尾部 | 6 | 8 | 1.232 | 0.540 |
骶1~4 | 14 | 34 | |||
其他 | 3 | 4 | |||
手术体位 | 俯卧位 | 21 | 42 | 0.000 | 1.000 |
其他 | 2 | 4 | |||
肿瘤分类 | 良性 | 12 | 21 | 0.029 | 1.000 |
恶性 | 11 | 25 | |||
手术时长(h) | <3h | 12 | 5 | 22.790 | 0.000 |
3h~ | 9 | 11 | |||
4h~ | 2 | 17 | |||
5h~ | 0 | 13 | |||
术中出血量(mL) | <400mL | 13 | 16 | 8.498 | 0.037 |
400mL~ | 6 | 9 | |||
800mL~ | 3 | 9 | |||
1200mL~ | 0 | 12 |
B | S.E. | Wald | P | Exp(B) | 95% C.I. | ||
|---|---|---|---|---|---|---|---|
下限 | 上限 | ||||||
术中出血量（ml） | -2.89 | 1.22 | 5.62 | 0.02 | 0.06 | 0.01 | 0.61 |
手术时长（h） | 0.49 | 0.24 | 4.17 | 0.04 | 1.63 | 1.02 | 2.62 |
所输血液成分 | 分组 | n,% |
|---|---|---|
悬浮红细胞(U) | 2~ | 23（33.33） |
4~ | 14（20.29） | |
8~ | 2（2.90） | |
12~ | 7（14.29） | |
血浆（ml) | 200~ | 1（1.45） |
400~ | 8（11.59） | |
800~ | 8（11.59） | |
1600~ | 5（10.20） | |
血小板(治疗量） | 1 | 1（1.45） |
2 | 2（2.90） |
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APA Style
Gui-yu, W., Ying, L., Xiao-min, F., Chao, W., Dong-jiang, X. (2026). Retrospective Analysis of Influencing Factors for Perioperative Blood Transfusion in Patients with Sacral Tumors. Science Research, 14(5), 308-313. https://doi.org/10.11648/j.sr.20261405.16
ACS Style
Gui-yu, W.; Ying, L.; Xiao-min, F.; Chao, W.; Dong-jiang, X. Retrospective Analysis of Influencing Factors for Perioperative Blood Transfusion in Patients with Sacral Tumors. Sci. Res. 2026, 14(5), 308-313. doi: 10.11648/j.sr.20261405.16
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Download@article{10.11648/j.sr.20261405.16,
author = {Wu Gui-yu and Liu Ying and Feng Xiao-min and Wang Chao and Xu Dong-jiang},
title = {Retrospective Analysis of Influencing Factors for Perioperative Blood Transfusion in Patients with Sacral Tumors},
journal = {Science Research},
volume = {14},
number = {5},
pages = {308-313},
doi = {10.11648/j.sr.20261405.16},
url = {https://doi.org/10.11648/j.sr.20261405.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sr.20261405.16},
abstract = {Objective: To explore the risk factors for perioperative blood transfusion in patients with sacral tumors and provide a basis for clinical blood management. Methods: The clinical data of 69 patients with sacral tumors undergoing surgery were retrospectively analyzed. The patients were divided into the transfusion group (n=46) and the non-transfusion group (n=23) based on whether they received allogeneic red blood cell transfusion during the perioperative period. Univariate analysis was used to screen the risk factors, and variables with P0.05). Multivariate Logistic regression analysis showed that operation duration (OR=1.63, P=0.04) and intraoperative blood loss (OR=0.06, P=0.02) were independent risk factors for perioperative blood transfusion. Among the transfusion patients, 2-4 units of suspended red blood cells accounted for 33.33%, more than 12 units accounted for 14.29%, and more than 1600mL of plasma accounted for 10.20%. Conclusion: The perioperative blood transfusion rate of patients with sacral tumors is relatively high (66.7%). The prolongation of operation time and the increase of intraoperative blood loss are independent risk factors for perioperative blood transfusion. In clinical practice, attention should be focused on high-risk patients with long operation time and large intraoperative blood loss. Preoperative blood type identification and screening for irregular antibodies should be completed, and sufficient blood reserves (8 units of red blood cells recommended) should be prepared. The transfusion department should establish a close communication and collaboration mechanism with the clinical department to ensure the supply of blood in case of sudden large blood demand, to reduce the need for allogeneic blood transfusion, reduce transfusion-related complications, and improve patient prognosis.},
year = {2026}
}
TY - JOUR T1 - Retrospective Analysis of Influencing Factors for Perioperative Blood Transfusion in Patients with Sacral Tumors AU - Wu Gui-yu AU - Liu Ying AU - Feng Xiao-min AU - Wang Chao AU - Xu Dong-jiang Y1 - 2026/09/04 PY - 2026 N1 - https://doi.org/10.11648/j.sr.20261405.16 DO - 10.11648/j.sr.20261405.16 T2 - Science Research JF - Science Research JO - Science Research SP - 308 EP - 313 PB - Science Publishing Group SN - 2329-0927 UR - https://doi.org/10.11648/j.sr.20261405.16 AB - Objective: To explore the risk factors for perioperative blood transfusion in patients with sacral tumors and provide a basis for clinical blood management. Methods: The clinical data of 69 patients with sacral tumors undergoing surgery were retrospectively analyzed. The patients were divided into the transfusion group (n=46) and the non-transfusion group (n=23) based on whether they received allogeneic red blood cell transfusion during the perioperative period. Univariate analysis was used to screen the risk factors, and variables with P0.05). Multivariate Logistic regression analysis showed that operation duration (OR=1.63, P=0.04) and intraoperative blood loss (OR=0.06, P=0.02) were independent risk factors for perioperative blood transfusion. Among the transfusion patients, 2-4 units of suspended red blood cells accounted for 33.33%, more than 12 units accounted for 14.29%, and more than 1600mL of plasma accounted for 10.20%. Conclusion: The perioperative blood transfusion rate of patients with sacral tumors is relatively high (66.7%). The prolongation of operation time and the increase of intraoperative blood loss are independent risk factors for perioperative blood transfusion. In clinical practice, attention should be focused on high-risk patients with long operation time and large intraoperative blood loss. Preoperative blood type identification and screening for irregular antibodies should be completed, and sufficient blood reserves (8 units of red blood cells recommended) should be prepared. The transfusion department should establish a close communication and collaboration mechanism with the clinical department to ensure the supply of blood in case of sudden large blood demand, to reduce the need for allogeneic blood transfusion, reduce transfusion-related complications, and improve patient prognosis. VL - 14 IS - 5 ER -
Department of Blood Transfusion, Capital Medical University Affiliated Beijing Jishuitan Hospital, Beijing, China
Department of Blood Transfusion, Capital Medical University Affiliated Beijing Jishuitan Hospital, Beijing, China
Department of Blood Transfusion, Capital Medical University Affiliated Beijing Jishuitan Hospital, Beijing, China
Department of Blood Transfusion, Capital Medical University Affiliated Beijing Jishuitan Hospital, Beijing, China
Department of Blood Transfusion, Capital Medical University Affiliated Beijing Jishuitan Hospital, Beijing, China
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