Volume 11, Issue 1, March 2025

  • Research Article

    Study of the Bioavailability of Methyluracil in Vitro and Its Biocompatibility in Vivo in the Composition of Polyurethane Implant Material

    Dmytro Kuliesh*, Ludmila Nechaeva, Vira Hrytsenko, Rita Rozhnova

    Issue: Volume 11, Issue 1, March 2025
    Pages: 1-6
    Received: 17 July 2025
    Accepted: 4 August 2025
    Published: 20 August 2025
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    Abstract: The development of polymer implant materials for use as drug carriers is an urgent task today. The aim of this work was to study the bioavailability of methyluracil when immobilized on a polyurethane carrier in vitro, as well as to study the biocompatibility of the obtained material when conducting model operations on experimental animals in vivo. ... Show More