Research Article
Anti-Inflammatory Activity of Viscum album D6 Preparations in Eye Drops Formulation
Issue:
Volume 6, Issue 1, March 2025
Pages:
1-6
Received:
17 November 2024
Accepted:
25 December 2024
Published:
16 January 2025
DOI:
10.11648/j.rd.20250601.11
Downloads:
Views:
Abstract: Viscum album is widely recognized in complementary medicine for its antidiabetic, analgesic, anti-inflammatory, and antitumor properties. This plant contains various bioactive compounds, allowing for the observation of diverse pharmacological effects. The present study aimed to evaluate, by in vitro testing, the effect of the Viscum album 6DH eye drops on ocular inflammation using human keratinocytes (HaCaT) and human mesenchymal stem cells (MSCs). HaCaT cells were utilized for the MTT cytotoxicity assay, which determined the optimal concentration of the eye drops (8 µL/mL) for subsequent experiments. In the scratch assay, treatment with the eye drops resulted in significantly enhanced scratch closure compared to the control group. In parallel, MSCs were employed for cytokine analysis. Inflammation was induced using lipopolysaccharides (LPS) prior to treatment with the eye drops. Results indicated a reduction in the pro-inflammatory cytokines IL-8 and IL-12p70 following treatment. These findings suggest that the anti-inflammatory properties of Viscum album can be effectively harnessed in this pharmaceutical form (homeopathic eye drops), offering potential therapeutic applications for the treatment of ocular inflammation.
Abstract: Viscum album is widely recognized in complementary medicine for its antidiabetic, analgesic, anti-inflammatory, and antitumor properties. This plant contains various bioactive compounds, allowing for the observation of diverse pharmacological effects. The present study aimed to evaluate, by in vitro testing, the effect of the Viscum album 6DH eye d...
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Research Article
What is Artificial Entrepreneurship? The Influence of AI for the Creative Destruction of Schumpeter
Tobias Kollmann*
Issue:
Volume 6, Issue 1, March 2025
Pages:
7-29
Received:
27 January 2025
Accepted:
12 February 2025
Published:
25 March 2025
Abstract: Artificial Intelligence (AI) is revolutionising the economy and society by automating processes, driving innovation and enabling new business models, leading to a significant increase in productivity and competitiveness. Until now, the aspect of "Innovation Development" has always been assigned to Humans as Entrepreneurs (or Intrapreneurs), but in the course of AI-Development, the question must increasingly be asked whether AI will not only take on a passive support role in this field but also an active development and decision-making role. Against this background, there is a growing need for research in the field of “Human versus Machine” for driving innovation and enabling new business models. (Human) Entrepreneurs are characterised by recognising, evaluating and exploiting entrepreneurial opportunities. According to Schumpeter's understanding, the "Human Entrepreneur" appears in particular as an innovator by developing innovative ideas through their creative power and establishing them on the market. To do this, they must make entrepreneurial decisions based on the available information and data. However, this decision-making process based on information or data is increasingly being taken over by Artificial Intelligence, which is much more powerful in handling this information or data. However, what happens when Artificial Intelligence not only supports the decision-making process of a "Human Entrepreneur" in a formative way but also takes it over as an "Artificial Entrepreneur" based on its own transformative creativity? The aim of the following article is to conceptually describe the prerequisites for the takeover of creative destruction by a machine in the sense of Schumpeter. The result is the development of a Framework which forms the basis for a new field of research: "Artificial Entrepreneurship".
Abstract: Artificial Intelligence (AI) is revolutionising the economy and society by automating processes, driving innovation and enabling new business models, leading to a significant increase in productivity and competitiveness. Until now, the aspect of "Innovation Development" has always been assigned to Humans as Entrepreneurs (or Intrapreneurs), but in ...
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