01About This Special Issue
Special Issue: Several advances in oral immunity have been made in relevance literature. In this issue a series of review articles to be invented concerning; Oral microbiome, oral natural immunity, oral mucosal immune responses ,oral cytokines and diseases ,complement and oral diseases.In addition to research papers on IgA in Peridontitis and gingivitis as well as hypercomplementemia in peridontitis.Aims and Scope
1. Mapping oral mciroflora
2. Oral mucosal compartment
3. Role of mucosal immunity
4. Role of oral cytokines
5. IgA in chronic oral diseases
6. Oral versus systemic hypercomplementemia
02Meet the Guest Editors
Our distinguished editors bring deep subject-matter expertise to curate high-quality research and ensure a rigorous peer-review process.
Lead Guest Editor
Ibrahim Mohamed Saeed Shnawa
College of Biotechnology, University of Qasim, Qasim, Iraq
Guest Editor
Vinayak Raghunathan
Department of Periodontics and Oral Implantology, The Oxford Dental College and Hospital, Bangalore, India
Guest Editor
Shuli Liu
Department of Oral and Maxillofacial–Head and Neck Oncology, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, China
03Published Articles
The following articles have been published in this special issue.
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The Interplay of the Local Microbiome with Oral Mucosal Immune Compartment: Minireview
Issue: Volume 3, Issue 4-1, July 2015Pages: 17-19Received: 20 May 2015Accepted: 20 May 2015Published: 29 May 2015DOI: 10.11648/j.ajbls.s.2015030401.16Downloads:Views:Abstract: The oral microbiome is formed and functioned in balanced state during health and in an unbalanced state in the disease conditions. Microbiome in the oral compartment combats the weapons of the invading microbial pathogens .Now , there are a specific microbiome signature in each of the cases of health and disease. Oral microbiome expressed; probioti... Show More -
Oral Mucosal Tolerance Versus Systemic Immune Response to Salmonella typhi Antigen
Issue: Volume 3, Issue 4-1, July 2015Pages: 13-16Received: 17 March 2015Accepted: 28 March 2015Published: 23 April 2015DOI: 10.11648/j.ajbls.s.2015030401.15Downloads:Views:Abstract: It was demonstrated that the oral vaccine application of Salmonella typhi antigen can activate low antibody agglutinin titer (mean:40±0) comparing with high agglutination titer induced by Intramuscular administration of Salmonella typhi antigen (mean 560.0 ± 51.64) as well as anti-Salmonella typhi IgG ELIZA shows high mean index value(mean = 0.695... Show More -
IgM-IgG-IgA Secondary Mixed Cryoglobulinemia Associated with Pediatric Tonsillitis
Issue: Volume 3, Issue 4-1, July 2015Pages: 10-12Received: 28 February 2015Accepted: 5 March 2015Published: 12 March 2015DOI: 10.11648/j.ajbls.s.2015030401.14Downloads:Views:Abstract: A cryoprotein was separated from sera of the pediatric tonsillitis patients. Such protein characterized as: percipitable at 4c , dissolvable at 37c and repercipitable at 4c. It showed gelatinous or crystalline texture. The immunochemical quantitation using single radial immune diffusion for immunoglobulin isotypes revealed mixed IgM-IgG-IgA isotype... Show More -
Oral Mucosal Immune Tolerance Versus Oral Immune Silencing: Mini Review
Issue: Volume 3, Issue 4-1, July 2015Pages: 7-9Received: 18 February 2015Accepted: 2 March 2015Published: 6 March 2015DOI: 10.11648/j.ajbls.s.2015030401.13Downloads:Views:Abstract: Oral mucosal tolerance a phenomenon among others in the common mucosal immune system. The mechanisms behind which are multiple. Three main opinions are being raised up .First ,tolerant cells emerged within the gut mucosa and migrates to oral mucosa suppressing immune function ,the second holds that tolerant cells evolved with in the sublingual sali... Show More -
Normo Hyper and Extreme Hypercomplementemia in Human Chronic Periodontitis
Issue: Volume 3, Issue 4-1, July 2015Pages: 4-6Received: 11 February 2015Accepted: 13 February 2015Published: 2 March 2015DOI: 10.11648/j.ajbls.s.2015030401.12Downloads:Views:Abstract: Fourty-Nine chronic periodontitis patients were diagnosed by the dentist of the team. Of which 27 were generalized chronic and the other 22 were localized chronic periodontitis. Ten subjects with normal mouth hygienewere considered as controls. Blood,and saliva samples were collected from both of the test patients and controls. Sera, saliva and sal... Show More -
Immunoglobulin a in Chronic Periodontitis Patients
Issue: Volume 3, Issue 4-1, July 2015Pages: 1-3Received: 11 February 2015Accepted: 13 February 2015Published: 2 March 2015DOI: 10.11648/j.ajbls.s.2015030401.11Downloads:Views:Abstract: Fourty-nine chronic periodontitis patients were diagnosed by dentist .Of which 27 were with generalized chronic periodontitis and 22 were with localized chronic periodontitis. The disease was prevalent among the age group range from 20 to 44 years old. Ten apparently healthy normal subjects were elected as control .Sera , saliva, salivary proteins ... Show More


