Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden

Shady Hussein Elhusseiny; Mahmoud Mohamed Abdo; Shaheer Kamal George; Sherif Ibraheem Eltantawy

doi:doi:10.11648/j.ccr.20210501.15

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Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden

Shady Hussein Elhusseiny, Mahmoud Mohamed Abdo, Shaheer Kamal George, Sherif Ibraheem Eltantawy

Published in Cardiology and Cardiovascular Research (Volume 5, Issue 1)

Received: 7 January 2021 Accepted: 18 January 2021 Published: 28 January 2021

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Abstract

The efficacy of thrombus aspiration (TA) for various culprit lesions in ST-segment elevation myocardial infarction has not been sufficiently evaluated, this directed recent randomized clinical trials to question its clinical benefits. We aimed to assess the efficacy of TA based primary percutaneous coronary intervention (PCI) in STEMI subgroup with heavy thrombus burden (TB) and compare it with conventional PCI in different STEMI subgroups. A comparative prospective study conducted on 60 patients (age 22–82 years) with acute STEMI who underwent primary PCI at our hospital from January 2016 to January 2017. Study population were divided into two groups: 1) patients with heavy TB or absence of flow after passage of guidewire underwent TA before stent deployment (test group, 30 patients) and 2) patients underwent conventional PCI (comparative group, 30 patients). Median follow-up duration was 5 days. Statistically significant differences; regarding final angiographic flow assessed by thrombolysis in myocardial infarction (TIMI) flow were found between the two groups in (TIMI) 0 before patients on TIMI flow after (TIMI 3 after 75.9 vs. 58.8%, TIMI 2 after 24.1 vs. 17.6%; P=0.05). In Conclusions; It is preferable to use TA before stenting in patients with STEMI with TIMI 0 flow before intervention.

Published in	Cardiology and Cardiovascular Research (Volume 5, Issue 1)
DOI	10.11648/j.ccr.20210501.15
Page(s)	25-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Percutaneous Coronary Intervention, Stents, Reperfusion

References

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APA Style

Shady Hussein Elhusseiny, Mahmoud Mohamed Abdo, Shaheer Kamal George, Sherif Ibraheem Eltantawy. (2021). Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiology and Cardiovascular Research, 5(1), 25-32. https://doi.org/10.11648/j.ccr.20210501.15

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ACS Style

Shady Hussein Elhusseiny; Mahmoud Mohamed Abdo; Shaheer Kamal George; Sherif Ibraheem Eltantawy. Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiol. Cardiovasc. Res. 2021, 5(1), 25-32. doi: 10.11648/j.ccr.20210501.15

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AMA Style

Shady Hussein Elhusseiny, Mahmoud Mohamed Abdo, Shaheer Kamal George, Sherif Ibraheem Eltantawy. Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiol Cardiovasc Res. 2021;5(1):25-32. doi: 10.11648/j.ccr.20210501.15

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@article{10.11648/j.ccr.20210501.15,
  author = {Shady Hussein Elhusseiny and Mahmoud Mohamed Abdo and Shaheer Kamal George and Sherif Ibraheem Eltantawy},
  title = {Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden},
  journal = {Cardiology and Cardiovascular Research},
  volume = {5},
  number = {1},
  pages = {25-32},
  doi = {10.11648/j.ccr.20210501.15},
  url = {https://doi.org/10.11648/j.ccr.20210501.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20210501.15},
  abstract = {The efficacy of thrombus aspiration (TA) for various culprit lesions in ST-segment elevation myocardial infarction has not been sufficiently evaluated, this directed recent randomized clinical trials to question its clinical benefits. We aimed to assess the efficacy of TA based primary percutaneous coronary intervention (PCI) in STEMI subgroup with heavy thrombus burden (TB) and compare it with conventional PCI in different STEMI subgroups. A comparative prospective study conducted on 60 patients (age 22–82 years) with acute STEMI who underwent primary PCI at our hospital from January 2016 to January 2017. Study population were divided into two groups: 1) patients with heavy TB or absence of flow after passage of guidewire underwent TA before stent deployment (test group, 30 patients) and 2) patients underwent conventional PCI (comparative group, 30 patients). Median follow-up duration was 5 days. Statistically significant differences; regarding final angiographic flow assessed by thrombolysis in myocardial infarction (TIMI) flow were found between the two groups in (TIMI) 0 before patients on TIMI flow after (TIMI 3 after 75.9 vs. 58.8%, TIMI 2 after 24.1 vs. 17.6%; P=0.05). In Conclusions; It is preferable to use TA before stenting in patients with STEMI with TIMI 0 flow before intervention.},
 year = {2021}
}

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TY  - JOUR
T1  - Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden
AU  - Shady Hussein Elhusseiny
AU  - Mahmoud Mohamed Abdo
AU  - Shaheer Kamal George
AU  - Sherif Ibraheem Eltantawy
Y1  - 2021/01/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ccr.20210501.15
DO  - 10.11648/j.ccr.20210501.15
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 25
EP  - 32
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20210501.15
AB  - The efficacy of thrombus aspiration (TA) for various culprit lesions in ST-segment elevation myocardial infarction has not been sufficiently evaluated, this directed recent randomized clinical trials to question its clinical benefits. We aimed to assess the efficacy of TA based primary percutaneous coronary intervention (PCI) in STEMI subgroup with heavy thrombus burden (TB) and compare it with conventional PCI in different STEMI subgroups. A comparative prospective study conducted on 60 patients (age 22–82 years) with acute STEMI who underwent primary PCI at our hospital from January 2016 to January 2017. Study population were divided into two groups: 1) patients with heavy TB or absence of flow after passage of guidewire underwent TA before stent deployment (test group, 30 patients) and 2) patients underwent conventional PCI (comparative group, 30 patients). Median follow-up duration was 5 days. Statistically significant differences; regarding final angiographic flow assessed by thrombolysis in myocardial infarction (TIMI) flow were found between the two groups in (TIMI) 0 before patients on TIMI flow after (TIMI 3 after 75.9 vs. 58.8%, TIMI 2 after 24.1 vs. 17.6%; P=0.05). In Conclusions; It is preferable to use TA before stenting in patients with STEMI with TIMI 0 flow before intervention.
VL  - 5
IS  - 1
ER  -

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Author Information

Shady Hussein Elhusseiny

Department of Cardiology-Faculty of Medicine, Mansoura University, Mansoura, Egypt
Mahmoud Mohamed Abdo

Department of Cardiology-Faculty of Medicine, Mansoura University, Mansoura, Egypt
Shaheer Kamal George

Department of Cardiology-Faculty of Medicine, Mansoura University, Mansoura, Egypt
Sherif Ibraheem Eltantawy

Department of Cardiology-Faculty of Medicine, Mansoura University, Mansoura, Egypt

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Shady Hussein Elhusseiny, Mahmoud Mohamed Abdo, Shaheer Kamal George, Sherif Ibraheem Eltantawy. (2021). Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiology and Cardiovascular Research, 5(1), 25-32. https://doi.org/10.11648/j.ccr.20210501.15

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ACS Style

Shady Hussein Elhusseiny; Mahmoud Mohamed Abdo; Shaheer Kamal George; Sherif Ibraheem Eltantawy. Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiol. Cardiovasc. Res. 2021, 5(1), 25-32. doi: 10.11648/j.ccr.20210501.15

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AMA Style

Shady Hussein Elhusseiny, Mahmoud Mohamed Abdo, Shaheer Kamal George, Sherif Ibraheem Eltantawy. Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden. Cardiol Cardiovasc Res. 2021;5(1):25-32. doi: 10.11648/j.ccr.20210501.15

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@article{10.11648/j.ccr.20210501.15,
  author = {Shady Hussein Elhusseiny and Mahmoud Mohamed Abdo and Shaheer Kamal George and Sherif Ibraheem Eltantawy},
  title = {Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden},
  journal = {Cardiology and Cardiovascular Research},
  volume = {5},
  number = {1},
  pages = {25-32},
  doi = {10.11648/j.ccr.20210501.15},
  url = {https://doi.org/10.11648/j.ccr.20210501.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20210501.15},
  abstract = {The efficacy of thrombus aspiration (TA) for various culprit lesions in ST-segment elevation myocardial infarction has not been sufficiently evaluated, this directed recent randomized clinical trials to question its clinical benefits. We aimed to assess the efficacy of TA based primary percutaneous coronary intervention (PCI) in STEMI subgroup with heavy thrombus burden (TB) and compare it with conventional PCI in different STEMI subgroups. A comparative prospective study conducted on 60 patients (age 22–82 years) with acute STEMI who underwent primary PCI at our hospital from January 2016 to January 2017. Study population were divided into two groups: 1) patients with heavy TB or absence of flow after passage of guidewire underwent TA before stent deployment (test group, 30 patients) and 2) patients underwent conventional PCI (comparative group, 30 patients). Median follow-up duration was 5 days. Statistically significant differences; regarding final angiographic flow assessed by thrombolysis in myocardial infarction (TIMI) flow were found between the two groups in (TIMI) 0 before patients on TIMI flow after (TIMI 3 after 75.9 vs. 58.8%, TIMI 2 after 24.1 vs. 17.6%; P=0.05). In Conclusions; It is preferable to use TA before stenting in patients with STEMI with TIMI 0 flow before intervention.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Efficacy of Thrombus Aspiration Adjunct to Primary Percutaneous Intervention in ST-elevation Myocardial Infarction Patients with Heavy Thrombus Burden
AU  - Shady Hussein Elhusseiny
AU  - Mahmoud Mohamed Abdo
AU  - Shaheer Kamal George
AU  - Sherif Ibraheem Eltantawy
Y1  - 2021/01/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ccr.20210501.15
DO  - 10.11648/j.ccr.20210501.15
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 25
EP  - 32
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20210501.15
AB  - The efficacy of thrombus aspiration (TA) for various culprit lesions in ST-segment elevation myocardial infarction has not been sufficiently evaluated, this directed recent randomized clinical trials to question its clinical benefits. We aimed to assess the efficacy of TA based primary percutaneous coronary intervention (PCI) in STEMI subgroup with heavy thrombus burden (TB) and compare it with conventional PCI in different STEMI subgroups. A comparative prospective study conducted on 60 patients (age 22–82 years) with acute STEMI who underwent primary PCI at our hospital from January 2016 to January 2017. Study population were divided into two groups: 1) patients with heavy TB or absence of flow after passage of guidewire underwent TA before stent deployment (test group, 30 patients) and 2) patients underwent conventional PCI (comparative group, 30 patients). Median follow-up duration was 5 days. Statistically significant differences; regarding final angiographic flow assessed by thrombolysis in myocardial infarction (TIMI) flow were found between the two groups in (TIMI) 0 before patients on TIMI flow after (TIMI 3 after 75.9 vs. 58.8%, TIMI 2 after 24.1 vs. 17.6%; P=0.05). In Conclusions; It is preferable to use TA before stenting in patients with STEMI with TIMI 0 flow before intervention.
VL  - 5
IS  - 1
ER  -

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