Evaluation of Serum Ferritin in Type 2 Diabetes Mellitus: An Observational Study from North Sulawesi, Indonesia
Diana Shintawati Purwanto,
Yanti Meilen Mewo,
Stefana Helena Margaretha Kaligis,
Edmond Leonard Jim
Issue:
Volume 7, Issue 4, December 2022
Pages:
103-108
Received:
22 September 2022
Accepted:
10 October 2022
Published:
18 October 2022
DOI:
10.11648/j.ijde.20220704.11
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Abstract: Diabetes mellitus is still an important health problem in Indonesia because the incidence is increasing every year and most patients do not achieve good and proper glycemic control. Analysis of blood ferritin levels in type 2 diabetes mellitus patients is considered limited in many areas. As a marker of iron stores in the body, elevated serum ferritin has been associated with microvascular and macrovascular complications of diabetes mellitus. This study aimed to determine the correlation between serum ferritin levels and fasting blood glucose, glycated hemoglobin (HbA1c), and other biochemical parameters in type 2 diabetes mellitus patients in North Sulawesi, Indonesia. A total of 108 diabetes mellitus patients were included in this cross-sectional study. Subjects were tested for blood pressure, body mass index, fasting blood glucose, hemoglobin, glycated hemoglobin (HbA1c), ferritin, urea, creatinine, uric acid, alanine aminotransferase, aspartate aminotransferase, cholesterol, and triglyceride. The averages of HbA1c% in the good, moderate, and poor groups were 5.70 ± 0.5%, 7.2 ± 0.6, and 10.1 ± 1.6, respectively. Increased fasting blood glucose, ferritin, urea, creatinine, and uric acid levels were observed along with worsening glycemic status. There were significant correlations between serum ferritin and fasting blood glucose, glycated hemoglobin, and alanine aminotransferase (p < 0.05). There were significantly different mean ferritin values in the three groups of glycated hemoglobin, suggesting ferritin can be used as an indicator of control of glycemia and diabetic complications.
Abstract: Diabetes mellitus is still an important health problem in Indonesia because the incidence is increasing every year and most patients do not achieve good and proper glycemic control. Analysis of blood ferritin levels in type 2 diabetes mellitus patients is considered limited in many areas. As a marker of iron stores in the body, elevated serum ferri...
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Role of Resistance Training (RT) in Type 2 Diabetes Mellitus with Normal Body Mass (BMI): A Report of 3 Cases
Vaidehi Revandkar,
Bipin Gond,
Rahul Mandole,
Gurudatt Amin,
Pravin Ghadigaonkar,
Ranjeeta Kewat
Issue:
Volume 7, Issue 4, December 2022
Pages:
109-121
Received:
1 August 2022
Accepted:
23 August 2022
Published:
10 November 2022
DOI:
10.11648/j.ijde.20220704.12
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Abstract: Background: DM is often treated with a range of anti-diabetic medications (ADD), which can be used alone or in combination with other medicines from various classes. However, there are several side effects related with the use of these ADDs, including dizziness, fainting, gastrointestinal distress, dyspepsia, diabetic ketoacidosis, and so on. Diabetic patients' quality of life is already impacted by uncomfortable symptoms. Comprehensive diabetic care (CDC) is an Ayurvedic treatment that combines Panchkarma (five internal bio-cleansing therapies), a purification procedure, the administration of herbal medications to patients, and nutrition therapy. Physical activity or exercise particularly resistance training (RT) is thought to be a good therapy regimen for T2DM. Case information: Case 1 was a 38-year-old male, who was known case of type 2 DM since 2 years came with chief complaint of generalized weakness. He was diagnosed with T2DM 2 years back. Case 2 was a 50 years old male who came with the chief complaints of arthralgia and dyspnea on exertion grade 1. The patient was known case of T2DM and hypertension since 2 years. Case 3 was a 52 years old male who came with the chief complaints of extreme pricking pain in both the lower limbs. The patient was known case of T2DM since 5 years. These patients had taken oral antidiabetic drugs in the past. All these patients were given comprehensive diabetes care (CDC) along with resistance training exercise on daily basis. Results: Body Mass Index and lean body mass was maintained in first two cases. HbA1c reduction was seen in all the three cases throughout the study period. 2 of 3 patients showed complete adherence to therapy. Conclusion: There is synergistic action of CDC therapy along with resistance training exercise in patients of type 2 Diabetes Mellitus with low to normal BMI.
Abstract: Background: DM is often treated with a range of anti-diabetic medications (ADD), which can be used alone or in combination with other medicines from various classes. However, there are several side effects related with the use of these ADDs, including dizziness, fainting, gastrointestinal distress, dyspepsia, diabetic ketoacidosis, and so on. Diabe...
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A Jordanian Multidisciplinary Consensus Statement on the Management of Type 2 Diabetes
Munther Al-Momani,
Muneer Ali Abu Alsamen,
Eyas Al Mousa,
Mohammad Ghnaimat,
Fares Haddad,
Mahmoud Hashim,
Mohammad Jabary,
Abdelkarim Khawaldeh,
Taroub Khoury,
Nadima Shegem,
Mazen Matalka
Issue:
Volume 7, Issue 4, December 2022
Pages:
122-136
Received:
3 November 2022
Accepted:
17 November 2022
Published:
23 November 2022
DOI:
10.11648/j.ijde.20220704.13
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Abstract: Background: The prevalence of type 2 diabetes (T2D) is increasing in Jordan and cardiovascular disease (CVD) is considered the leading cause of morbidity and mortality among patients with T2D patients. New data emerged with novel antihyperglycemic agents that demonstrated reduction in cardiorenal outcomes. Aims: The aims of the expert panel were to provide a multidisciplinary consensus approach to the screening, diagnosis, controlling cardiovascular risk factors, treatment, and monitoring of T2D. In addition, the panel’s aim was to develop an algorithm, incorporating new data to serve as an easy-to-use tool by health care providers (HCPs) to ultimately improve the decision-making process and outcome. Methods: A panel of experts from different specialties representing various medical societies met to discuss and review all the relevant T2D literature and the related international clinical practice guidelines on T2D. The panel evaluated and developed a comprehensive understanding of the current situation in Jordan, addressing the screening, diagnosis, pharmacological treatment, management, and monitoring parameters of T2D. Results: The expert panel established criteria for screening and diagnosis of patients with T2D driven by international clinical practice guidelines. The panel addressed all the cardiovascular (CV) risk factors associated with T2D and developed a risk stratification strategy. Accordingly, treatment recommendations were proposed based on the evidence of reduction of cardiorenal events and hospitalizations for heart failure (HFF) with the different options of pharmacological treatments. A treatment algorithm was drafted to provide guidance to the HCPs on the management of T2D. Conclusion: The focus of treatment in T2D has shifted from just controlling hyperglycemia towards reduction in cardio-renal complications. New data with two disease-modifying agents have changed the landscape of T2D treatment. It was important to develop a consensus statement with a multidisciplinary approach to provide HCPs with useful tools to use in the management of T2D, including a treatment algorithm. These recommendations would help increase awareness about the management of T2D in Jordan with the ultimate goal of improving cardiorenal outcomes.
Abstract: Background: The prevalence of type 2 diabetes (T2D) is increasing in Jordan and cardiovascular disease (CVD) is considered the leading cause of morbidity and mortality among patients with T2D patients. New data emerged with novel antihyperglycemic agents that demonstrated reduction in cardiorenal outcomes. Aims: The aims of the expert panel were to...
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