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Volume 1, Issue 2, April 2013

Modeling the Mitogen Activated Protein (MAP)-Kinase Pathway Using Ordinary Differential Equations

Sharadwata Pan, Sameer E. Mhatre

Issue: Volume 1, Issue 2, April 2013

Pages: 6-9

Received: 30 April 2013

Published: 10 June 2013

DOI: 10.11648/j.cbb.20130102.11

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Abstract: Mitogen Activated Protein (MAP) Kinase pathway is central to comprehend the key cellular signal transduction mechanisms in animal physiology, including human beings. Modeling MAP Kinase pathway has two main applications: deciphering a transient response of three main components (MAPKKK, MAPKK and MAPK) to regulate signaling and utilizing the models... Show More

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