International Journal of Pharmacy and Chemistry

Archive

Volume 7, Issue 1, January 2021

  • Determination of Ferrous Iron in Ferric Chloride Hexahydrate

    Bai Xiaoguang, Wang Zhengda, Wu Xudong, Duan Shufen, Liu Aihua, Cheng Xiao

    Issue: Volume 7, Issue 1, January 2021
    Pages: 1-4
    Received: 25 March 2019
    Accepted: 24 June 2020
    Published: 10 February 2021
    DOI: 10.11648/j.ijpc.20210701.11
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    Abstract: Objective: As a pharmaceutical raw material, ferric chloride hexahydrate has been included in the British Pharmacopoeia, the European Pharmacopoeia (2008) and the United States Pharmacopoeia (2015), and there are detailed discussions on quality standards and testing methods. Ferric chloride hexahydrate has not been included in the Chinese Pharmacop... Show More
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  • Stability of Reconstituted Amoxicillin and Potassium Clavulanate Oral Suspensions Marketed in the Democratic Republic of the Congo

    Mankulu Kakumba Jocelyn, Mavanga Mabaya Timothy, Bayebila Menanzambi Tresor, Tshienda Katende Milka, Mbenza Puati Adelard, Mbinze Kindenge Jeremi, Kimbeni Malongo Tresor

    Issue: Volume 7, Issue 1, January 2021
    Pages: 5-12
    Received: 14 December 2020
    Accepted: 22 December 2020
    Published: 23 February 2021
    DOI: 10.11648/j.ijpc.20210701.12
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    Abstract: Amoxicillin and Clavulanate potassium oral suspensions are one of antibiotics combination mainly available as dry powders for reconstitution. Made of a β-lactam molecule with a β-lactamase inhibitor, this combination existence can be justified by the potency of Clavulanate potassium which protects Amoxicillin against bacteria producing β-lactamases... Show More
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  • Tandem Cycloaddition-Cycloreversion of 2-pyrone and 1,4-oxazinone with Acetylene - A DFT Insight

    Padmanaban Kalpana, Lakshminarayanan Akilandeswari, Ponnambalam Venuvanalingam

    Issue: Volume 7, Issue 1, January 2021
    Pages: 13-21
    Received: 5 December 2020
    Accepted: 18 January 2021
    Published: 27 February 2021
    DOI: 10.11648/j.ijpc.20210701.13
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    Abstract: Reaction of either 2-pyrone or 1,4-oxazinone with acetylene follows the sequence of cycloaddition - cycloreversion through concerted mechanism. Transition states for both cycloaddition and cycloreversion pathways have been obtained in both the cases by modelling the reactions at B3LYP/6-31g (d) level. Cycloreversion is faster than cycloaddition in ... Show More
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