Archive:: American Journal of Laboratory Medicine:: Science Publishing Group

Volume 9, Issue 3, June 2024

Case Report
Agranulocytosis Induced by Overdosage of Mercaptopurine: A Case Report

Touria El Bardi^*, Assia El Ouarradi, Salma Rouhi, Wafae Quiddi, Sanae Sayagh

Issue: Volume 9, Issue 3, June 2024

Pages: 23-28

Received: 28 June 2024

Accepted: 29 July 2024

Published: 30 August 2024

DOI: 10.11648/j.ajlm.20240903.11

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Abstract: Drug-induced agranulocytosis (DIAG) is a rare but potentially fatal hematological complication. Thiopurines, such as mercaptopurine (6-MP), are widely used in the treatment of chronic inflammatory bowel diseases (IBD), but can cause myelotoxicity due to the accumulation of active metabolites. We report the case of a 48-year-old woman with ulcerativ... Show More

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Review Article
Validation Procedures in Medical Laboratory Testing: A Systematic Review of Best Practices

Abdalla Eltoum Ali^*, Alneil Mohammed Hamza, Haidar Eltayeb Saleh

Issue: Volume 9, Issue 3, June 2024

Pages: 29-40

Received: 10 August 2024

Accepted: 2 September 2024

Published: 23 September 2024

DOI: 10.11648/j.ajlm.20240903.12

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Abstract: Background: Validation procedures are essential in medical laboratory testing to ensure the accuracy and reliability of test results. As laboratory technologies evolve, staying informed about the need for continuous updates and standardization of validation practices is crucial. This knowledge keeps us at the forefront of high-quality diagnostic se... Show More

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