Maryam Sani Lawal,Abdulsalami Mohammed Sani,Denwe Samuel Dangmwan,Usman Yahaya
Issue:
Volume 1, Issue 3, November 2016
Pages:
27-33
Received:
9 September 2016
Accepted:
22 September 2016
Published:
14 October 2016
DOI:
10.11648/j.bmb.20160103.11
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Abstract: Medicinal plants constitute the major component of traditional medicine practiced worldwide due to the economic viability, accessibility, and ancestral experience. Three medicinal plants (Boswelllia dalzielli Hutch, Carica papaya L. and Parkia clappertoniana Jacq) used locally in diarrheal treatment were investigated. This study was carried on isolated and confirmed strains of multi-drug resistant isolates of salmonallae and shigellae bacteria isolated from diarrheal patients in kaduna metropolis, Nigeria. The antidiarrheal activity of the three plant extracts against multidrug resistant strains of Shigella and Salmonella was performed by agar well diffusion method using standard guidelines. The findings indicated that Boswelllia dalzielli, Carica papaya and Parkia clappertoniana had growth inhibitory effect against the tested bacteria. Ethanolic extract of Boswelllia dalzielli exhibited the highest inhibitory effect at 100mg/ml concentration on both Salmonella and Shigella isolates. When the results were statistically analyzed using Duncan's multiple range test (P<0.05), the highest efficacy was recorded with the ethanol extracts of Boswelllia dalzielli (26.00 ± 1.00). On the basis of these findings, it can be assumed that ethanol extracts of Boswelllia dalzielli, Carica papaya and Parkia clappertoniana could be potential sources for antidiarrheal drugs.Abstract: Medicinal plants constitute the major component of traditional medicine practiced worldwide due to the economic viability, accessibility, and ancestral experience. Three medicinal plants (Boswelllia dalzielli Hutch, Carica papaya L. and Parkia clappertoniana Jacq) used locally in diarrheal treatment were investigated. This study was carried on isol...Show More
Abstract: A bioreactor with Pseudomonas cepacia lipase (PCL) immobilized on the inner wall was conveniently prepared by adding lipase powder and the right amount of water to a conical flask and keeping it with mouth open in an incubator shaker at 37°C and 170 rpm for more than 10 h. The bioreactor was employed on resolution of (R, S)-1-chloro-3-(1-naphthyloxy)-2-propanol by catalyzing transesterification of it with vinyl acetate. It was showed that the wall-PCL behaved an excellent catalytic activity being 10 folds of native PCL in terms of conversion, and high enantioselectivity E = 110. And also the depressed activity of immobilized PCL owing to frequently use in organic phase could be reactivated easily by again shaking bioreactor under the aforesaid conditions after adding water. The enhanced activity was attributed to the simulation on interfacial activation mechanism of lipases at water/oil interface.Abstract: A bioreactor with Pseudomonas cepacia lipase (PCL) immobilized on the inner wall was conveniently prepared by adding lipase powder and the right amount of water to a conical flask and keeping it with mouth open in an incubator shaker at 37°C and 170 rpm for more than 10 h. The bioreactor was employed on resolution of (R, S)-1-chloro-3-(1-naphthylox...Show More
Abstract: Salinity is the most detrimental stress which impairs the growth and development of plants. Seven days old seedlings of two contrast genotypes of maize (Zea mays L.), two tolerant genotypes (9120 and Super Gold) and two susceptible genotypes (Pacific 984 and PS999), were subjected to 12 dSm-1 salinity stress for five days and contents of chlorophyll (Chl), carotenoid (Car), methylglyoxal (MG) as well as activities of glyoxalase I (Gly I) and glyoxalase II (Gly II) were investigated in fully expanded leaves. Loss of Chl and Car contents were higher in the susceptible genotypes compared to those in tolerant genotypes. Production of MG was also higher in the susceptible genotypes, Pacific 984 and PS999, compared to that in tolerant ones under salinity stress. Under salinity, Pacific 984 showed 105 and 91% higher MG over 9120 and Super Gold, respectively, while PS999 showed 75 and 63% higher MG over 9120 and Super Gold, respectively. On the other hand, both of the tolerant genotypes showed higher Gly I and Gly II activities as compared to susceptible genotypes which played important role in reducing cytotoxic MG in tolerant genotypes.Abstract: Salinity is the most detrimental stress which impairs the growth and development of plants. Seven days old seedlings of two contrast genotypes of maize (Zea mays L.), two tolerant genotypes (9120 and Super Gold) and two susceptible genotypes (Pacific 984 and PS999), were subjected to 12 dSm-1 salinity stress for five days and contents of chlorophyl...Show More