Research Article
Research into Predictive Factors for the Success or Failure of Radioiodine Therapy in the Treatment of Hyperthyroidism in Senegal
Issue:
Volume 14, Issue 1, June 2026
Pages:
1-7
Received:
1 December 2025
Accepted:
23 December 2025
Published:
16 January 2026
Abstract: Radioiodine therapy, a treatment method for hyperthyroidism, has been practiced in Senegal since 2016. The objective of our study was to identify predictive factors for the success or failure of radioiodine therapy in the management of hyperthyroidism in Senegal. A retrospective study was initiated in the nuclear medicine department of the Idrissa Pouye Hospital in Grand Yoff. It included the medical records of 172 patients followed for hyperthyroidism and treated with iodine-131. Demographic, clinical, paraclinical, and therapeutic aspects, as well as the evaluation of thyroid function at 3 and 6 months post-radioiodine therapy, were studied. The therapeutic efficacy at 3 months was 44.1%. Among the 17 patients who failed treatment, 12 were under 50 years of age. No statistically significant relationship was found between treatment failure and age (p = 0.877. However, the difference was statistically significant between men and women in terms of treatment failure (p=0.043). Vascular goiter, etiology, initial antithyroid drug use, and a short interval between antithyroid drugs (ATDs) discontinuation were factors contributing to treatment failure. A strong correlation existed between therapeutic efficacy and the administered dose (p=0.000). The 6-month success rate was 62.4%. The final therapeutic efficacy was 73.75%. Radioiodine therapy is an effective treatment for hyperthyroidism, achieving a high remission rate.
Abstract: Radioiodine therapy, a treatment method for hyperthyroidism, has been practiced in Senegal since 2016. The objective of our study was to identify predictive factors for the success or failure of radioiodine therapy in the management of hyperthyroidism in Senegal. A retrospective study was initiated in the nuclear medicine department of the Idrissa ...
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Research Article
Assessment of Pediatric Exposure to Ionizing Radiation in Diagnostic Radiography: A Study at Diamniadio Children’s Hospital
Issue:
Volume 14, Issue 1, June 2026
Pages:
8-13
Received:
9 January 2026
Accepted:
27 January 2026
Published:
9 February 2026
Abstract: Radiography, widely used for diagnostic purposes, represents a major source of exposure to ionizing radiation in children, a population particularly sensitive to the biological effects of radiation. Despite its widespread use, no study has previously assessed pediatric exposure to ionizing radiation in Senegal. This study was therefore conducted to measure and analyze exposure levels during routine radiographic examinations at the Diamniadio Children’s Hospital. A retrospective descriptive and analytical study was carried out from January 1 to June 30, 2022, within the radiology and medical biology departments. Demographic data and anatomical regions examined were collected from radiology registers. Data were entered using Microsoft Excel 2016 and analyzed with RStudio version 4.1.2. A total of 2820 children were included, with a median age of 4.35 years and a male-to-female ratio of 1.58. The [0-5 years [and [5-10 years [age groups were the most represented, accounting for 53.2% and 30.5% of cases, respectively. Chest and lower limb radiographs were the most frequently performed examinations across all age groups, with a higher exposure frequency observed in boys. These findings indicate that children undergo a substantial number of radiographic examinations, which may increase stochastic radiation effects. Therefore, strict application of radiological protection principles by radiologists and referring physicians is essential.
Abstract: Radiography, widely used for diagnostic purposes, represents a major source of exposure to ionizing radiation in children, a population particularly sensitive to the biological effects of radiation. Despite its widespread use, no study has previously assessed pediatric exposure to ionizing radiation in Senegal. This study was therefore conducted to...
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,
Woury Sow
